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HGH and Antibodies

Mallymore

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This question got me to register with you guys. Seen a lot of great videos by Dylan and have heard great things all around with this site.

My question is whats the deal with taking hgh and the possibility of it producing antibodies? Whst happens and how can u tell? Is it permanent?

Any good youtube videos as well?

Thank you
 
Some people will develop antibodies to the HGH that is exogenously injected into the body. It's uncommon but it does happen in some people.

https://www.ncbi.nlm.nih.gov/pubmed/15000864

Human growth hormone (hGH) is normally produced by acidophilic cells of the anterior lobe of the pituitary gland. Recombinant DNA technology has made it possible to produce rhGH. There have been reports of immunological reactions in patients treated with rhGH. For this reason, it is necessary to check sera of patients for presence of antibody against rhGH. Forty-seven children were treated for up to 6 months with recombinant human growth hormone (rhGH-Novo), 0.1 IU/Kg body weight, subcutaneously, three times weekly. The magnitude of growth response was similar to those expected from clinical experience with pituitary growth hormone. We examined sera for specific antibodies against rhGH by ELISA methods. Four patients developed serum antibodies against growth hormone. The analysis of these four sera by Dot blotting method also showed presence of antibodies against rhGH. In the sera of treated patients, pre-incubated with different concentration of rhGH, specific antibodies were detected by neutralizing assay. This finding was confirmed by ELISA technique. In conclusion, the main concern with anti-GH antibodies could be their ability to neutralize circulating growth hormone and inhibition its growth promoting effect.
 
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