I brought this up a week or so ago here:
http://www.evolutionary.org/forums/anabolic-steroids-peds/front-loading-long-esters-cycle-6523.html
Here is the conclusion on doubling the dose on week one:
Taking those numbers into account, it may be more logical to 3-4x the dose within some degree of reason for certain compounds (TREN!!) Anyways, this is a technique that had some popularity in the late 90's and early 00's. I had used it with satisfying results and plan to do so in the future. It doesn't seem like a popular idea on this forum but to that degree I might call into question the number of people who have actually tried it repeatedly. I'd venture to guess not many, but the rough math indicates that there would be benefit in doing so by the way of immediate increased BCL of the compound in question.
I will still of course use orals, but I use orals counter-intuitively I suppose... or at least against the grain of popularity. While it's common to use them to 'kick off' or 'jump start' a cycle, I see it as more of a cumulative benefit where as I find benefit from their inclusion from a results standpoint and less of a 'Timing' standpoint. The truth is that the only reason I wouldn't use most orals for a full 8-12 week cycle is because of the hepatotoxicity - but if that wasn't a factor I'd run them the full length of any cycle. To me, they are just another compound that aids in growth and not something that I use to augment another compound's ester-release schedule.
You asked for thoughts... I've done it repeatedly, those are my thoughts on it