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Thread: Milk Thistle killing making your oral steroids less effective.

  1. #1
    Newbie Brother SARMTAURUS's Avatar
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    Milk Thistle killing making your oral steroids less effective.

    I have noticed when ever I load up on Milk Thistle that I feel like my oral steroids are not kicking in on time. When I use to run cycles without liver support I could feel the orals within the first week, but now they seem kind of weak that I'm taking some extra milk thistle along with my bottle of N2guard. Should I drop the milk thistle and stay with the n2guard or take another course of action? I appreciate your feedback.

  2. #2
    EVO Veteran RickRock's Avatar
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    Are you dosing them at the same time as your orals? You should be dosing them at least 3-4 hours away from orals for best absorption and bioavailability

  3. #3
    Buff Brother Mike710's Avatar
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    And your sure that every other variable is accounted for? Not trying to be a dick but with this thread title I was kinda expecting research quality info. That being said, does anyone have any info on the protective actions of these products and their impact on methylated compounds in the liver?

  4. #4
    VIP gearhead's Avatar
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    bro milk thistle doesnt mess with steroids to the degree that it would be making them less effective...unlikely....
    Want to know Source info? Check Approved Sources section on Evo!

  5. #5
    Moderator stevesmi's Avatar
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    you can take peperine or grapefruit to make them for effective
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  6. #6
    Advanced Cyborg Brother
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    Like rick said you have to be careful when dosing these things because certain compounds and enzymes have an impact on breaking down the orals in digestion.. Keep it simple and smart and dose your orals accordingly

  7. #7
    EVO V.I.P JackSteel's Avatar
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    Quote Originally Posted by stevesmi View Post
    you can take peperine or grapefruit to make them for effective
    This. I would drink 8oz grapefruit juice with them.


    Sent from my iPhone using Tapatalk

  8. #8
    Power Lifter
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    I would dose all liver supports at night. or at least 5hrs after your last oral dose.


    I do think it plays a part in it. Also, some orals kick in faster than others. so that's going to be a factor too

  9. #9
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    I've read this before about Milk thistle, that it killed the effects of orals, I don't think I have ever experienced these side effects myself and I use Milk Thistle every time.

  10. #10
    Proficient Brother
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    Im running a PH and keep my doses separated by a few hours and dont feel any negative effects

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