CJC-1295 - with or without DAC????

[wolfpackalpha]

Wondered why people use CJC-1295 without DAC? how about with DAC? what does it all mean? why is it so confusing? well peptides are confusing. In this article, KB explains how you should use CJC and why.

Article: http://www.evolutionary.org/cjc-1295-with-without-dac

 

[Xtreme]

CJC-1295 DAC is a long-acting version of GHRH (Growth Hormone Releasing Hormone) which has had its half-life extended to 8 days. This is convenient as it means the product only needs to be injected once or twice per week for continuously elevated levels of Human Growth Hormone (HGH) and IGF-1. The advantage of using CJC-1295 DAC instead of actual HGH injections is that injecting HGH shuts down the body's own natural production and therefore when injections are ceased, the body’s ability to produce its own Growth Hormone may be impaired and take some time to recover. Since CJC-1295 DAC only stimulates the body's own GH production, this risk is not apparent.

 

[RickRock]

Very interesting. I have a lot to learn still about peptides

 

[JackSteel]

When did we find out it doesn't bleed?


Need Venom?? I'll bite

 

[stretch512]

Well due to the the fact that somatostatin will inevitably limit GH secretion so instead of a bleed think of it more as tiny pulses over a long period of time.

 

[gearhead]

so basically cjc can stop your normal GH release?....interesting......

 

[stretch512]

No somatostatin is a natural regulator of GH. CJC will not ever inhibit the production of GH. somatostatin however will always try to function in some cpacity as the body stroves to reach homeostasis. CJC - either the MOD GRF variety (Pulse spike) or the DAC version (Pulse Wave *not so much bleed) is probably the very best GHRH to use with a GHRP to achieve as close to dosing HGH levels as possible. CJC 1295 is a pretty complicated subject and it wasn't until recently that certain sentiments towards the DAC version really came to new light. No doubt both work great at what they do.

 

[jams472000]

When using CJC-DAC taking a somastotatin inhibitor is paramount. I've used Huperzine A 100mcg X3 times per day with great results.

The pituitary function using CJC-1295 + a somatostatin inhibitor (in this case acetylcholineesterase inhibitors), functions like this:
1) Exogenously supplied GH secretagogue CJC-1295 signals pituitary to release HGH, the amount of GH released is GREATER than without acetylcholineesterase inhibitor due to suppression of somatostatin.
2) Pituitary releases HGH creating a surge, however, somatostatin levels fail to rise after the release, therefore the pituitary remains responsive to secretagogues to signal more release of HGH, and the CJC-1295 fails to degrade due to its design thus lasting 24 hours a day for 8-10 days from an injection.
3) After the HGH is released, ANOTHER surge is immediatley signalled by the still active CJC-1295, and then another surge, and another, and another, and another, and another, and in the time span that 1 natural surge wouldve happened and another would be ready to go, probably 20x as many surges have already occurred.

 

[stretch512]

Thank you jams! Yes when you add in Huperzine A its going to really help things out even more. I actually use Huperzine on days when I hit legs hard too and I always love how it keeps me focused and actually I have seen myself lean out a bit while on it.

 

[MikeSnow]

To make this a little easier for those new to peptides the DAC is basically like an Enanthate ester of AAS while the no dac is like an Ace or Prop, a lot more goes into it than that in the pulses and bleeds. I ran cjc no dac with ghrp-2 and had nice strength and vascularity gains with some added sleep as a bonus. Benefit of the no dac is its cheaper but you have to pin 3x a day in most scenarios versus DAC is usually 2x a week

 

[Rockwilder]

So...would a combination of CJC-1295 WITH DAC, GHRP-2, and Huperzine A be a good combo?

 

[stretch512]

Yes bro actually one of the best. But personally I would switch the GHRP-2 for Ipamorelin and you can blast Ipamorelin higher than GHRP-2 as GHRP-2 does have a saturation point.

 

[stretch512]

Oh and Ipa has less sides than GHRP-2

 

[JackSteel]

I heard somewhere that ipamorelin was actually somewhat of a somatostatin inhibitor itself. Is that true? Or is it CJC that inhibits it?


Need Venom?? I'll bite

 

[hurricane]

Very good write up.I used to know alot of about peptides but have forgotten a great deal, been out of the game for awhile.

 

[dylangemelli]

A good cutting stack is cjc no dac( mod grf), ipam, hgh frag and huperzine... The pinning and eating schedule kind of sucks if you want to really get the most out of them as its quite frequent and you have to be very careful about when your eating especially with the frag or you could really lessen the effect but you can get some extra cutting with this stack as well, just not as pronounced as a sarms stack but can provide results...

 

[meathead96]

I've used CJC with dac at 2-3mg a week and also without dac at 100mcg 3-4 times a day stacked with ghrp2. I like both. DAC is easier because it has a much longer half life and less pinning is necessary.

 

[JackSteel]

I may try DAC one day. I'm curious.


Need Venom?? I'll bite

 

[jams472000]

Yes bro actually one of the best. But personally I would switch the GHRP-2 for Ipamorelin and you can blast Ipamorelin higher than GHRP-2 as GHRP-2 does have a saturation point.

I use CJC-1295/DAC 1mg twice per week every 4 days combined with GHRP-2 150mcg during the day upon rising, mid day, Post WO, and then before bed I switch to Ipamorelin at 300-500mcg since ipamorelin has a longer pulse and does not affect my apetite or causes prolactin issues.

Below you can read a quote from RussianStar so I take no credit for this, I wanted to share since it has helped me tremendously in maximizing my cycle with CJC-1295 DAC and GHRP-2/IPAMORELIN.

Growth hormone releasing hormone, In the healthy human body, large amounts of growth hormone are stored in the pituitary. The cells within the pituitary release growth hormone in response to signalling by GHRH (Growth Hormone Releasing Hormone) Then the peptide Ghrelin is (of which GHRPs - Growth Hormone Releasing Peptides - are mimetics), inhibited from releasing these stores by Somatostatin. GHRH and Ghrelin act on different populations of somatotropes (GH releasing cells). GHRP and Ghrelin increase the number of somatotropes releasing GH but not the amount released by each cell.
GHRH affects both the number of secreting cells and - moreso - the amount they are actualy able to secrete. GHRH and Ghrelin are released in specific patterns that vary depending on what the person involved is doing, or has been doing post-exercise. Now CJC-1295 DAC has been proven to stimulate slow wave sleep, and this is the period of sleep when most of your bodys repairing work takes place on muscles and tissues etc.
Now most people can and will make GH in their own pituitary gland, but not everyone can release it in the amounts needed, so from a medicinal point CJC-1295 DAC can be very beneficial.

" Now for its benefits to reach full potential, somatostatin needs to be inhibited because we have just seen it inhibits gh release, so by using a compound known as an Acetylcholineesterase inhibitor, now Acetylcholineesterase inhibits acetylcholine, and Acetylcholine inhibits somatostatin, so we want Acetylcholine in abundance, so by using an Acetylcholineesterase inhibitor, we allow acetylcholine to inhibit somatostatin, so increasing the amount of gh released when using CJC-1295DAC. Got it? Ok re read that last passage.
The best of these Acetylcholineesterase inhibitors and there are lots like..

Physostigmine
Huperzine A
Ladostigil,

Of the ones ive tried Huperzine A is the very best, and fairly cheap, now by adding ECGCs from green tea, as these ECGCs will transport the huperzine better so finding the receptor it needs the effects are even stronger on inhbiting the acetylcholineesterase.
Otherwise a really good one i used recently was Horny goat weed, its the only one i know that actualy increases acetylcholine as it inhibits the enzyme acetylcholinesterase.
Personally i rate this as my favourite peptide, you get nearly a constant surge in gh especialy if you add in say huperzine A, you get all the benefits of hgh, improved body composition, anabolic effects, injury recovery, improved skin, the full works, and at a very good price, far cheaper than real gh.
I have found that between 2000mcg -5000mcg a week has given me great results, increased bodymass over a 15 week period of nearly 9lbs, thats not weight gained, thats pure muscle and fat loss, You get all the same benefits of hgh, but you get them constantly, not just in one or 2 surges when you use the injections.
Now i would use this in fat deposits as i noticed a reduction when i did so quite quickly, and directly into a muscle with this is quite painfull to say the least, so thats a no no from me.
Expect to see results after just a couple of weeks, and the large amounts of igf-1 released will really add some muscle when incoorporated with a good diet and training regime.

There are no sides ive seen with cjc just positive ones except for the amazingly strong head rush you get about 20 mins after the injection, this a tell tale sign as to wether or not you have the real thing.
Remember the pulses are not as big as when you use GHRP-6, but rather its a continuous elevation of gh secretion peaking about 2 hours after the injection and staying elevated for 14 days. I use it 4 times a week in 500mcg doses and find this to be perfect for maintaining muscle when unable to train, say because of injury, and improving skin tone and health.
3500mcg is a far more anabolic dose and muscle mass will be noticeably improved after 4 weeks, and the skin will start to take on that shredded ultra thin look that gh users get before competitions.
All the benefits of real GH, less injections, less sides, a lot less money.... need i say more."