How do I manage e2 during a testosterone cycle?

[GoldenPlague]

I did a blood test and the results are the following:

Testosterone: 85.70 nmol/L (reference range: 8.64 - 29.00)
Estradiol: 153.00pmol/L (reference range: 28.0 - 156.0)

This corresponds to about 2300-2400 ng/dL (testosterone).

The results are good and I can say they exceeded my expectations. The free testosterone is also at a good level.

Despite being almost at the end of the reference range, I don't have any e2 side effects at all, not even slight water retention. Literally nothing.

These are the results I got from 250 mg testosterone a week.

What I want now is to increase the dose to 400 mg a week, which, if it follows a linear increase, will increase my e2 level well above the reference range, possibly up to 300 pmol/L.

Can someone tell me what to do now? I have tamoxifen and anastrozole. If I get an e2 level of 300 pmol/L, can I go with tamoxifen only, without using anastrozole?

Is 300 pmol/L potent enough to cause gyno, and if yes, will using only tamoxifen (20-40 mg a day) be enough to prevent gyno from 300 pmol/L, which is high but not extremely high, right? Answer this question, please, because it's the most important for me.

Also, I heard I need a proportional testosterone:estrogen ratio. That means, if my testosterone is high, my e2 should also be high. Is this true? So, according to this, if I have a T level that exceeds a specific level in terms of ng/dL, my e2 being within normal range will actually be harmful. Did I understand it correctly? If yes, what is that specific level in terms of ng/dL?

 

[RoidRage69]

If you’re not having any adverse side effects I wouldn’t do anything. Higher estrogen is actually better for you with higher test levels.

 

[GoldenPlague]

If you’re not having any adverse side effects I wouldn’t do anything. Higher estrogen is actually better for you with higher test levels.

Yes, I'm aware of protective properties of e2 and other benefits. But I really don't want gyno.

Are there any high e2 symptoms that happen BEFORE gyno? If yes, I will start using anastrozole when I get these symptoms due to high e2 that is still not high enough to cause gyno but is becoming.

For example, does acne occur before gyno when e2 is increasing?

 

[Noah Wixx]

Puffy nipples, itchy nipples, nipples getting sensitive or hurting, enlargement of breast tissue etc all signs to look out for.

 

[Losiol]

Yes, I'm aware of protective properties of e2 and other benefits. But I really don't want gyno.

Are there any high e2 symptoms that happen BEFORE gyno? If yes, I will start using anastrozole when I get these symptoms due to high e2 that is still not high enough to cause gyno but is becoming.

For example, does acne occur before gyno when e2 is increasing?

Itchy and puffy nipples is the clearest indicator in my opinion

 

[GoldenPlague]

Puffy nipples, itchy nipples, nipples getting sensitive or hurting, enlargement of breast tissue etc all signs to look out for.

Itchy and puffy nipples is the clearest indicator in my opinion

I'm on tamoxifen anyway. Currently, I take 20 mg a day, and I'm doing it preventively, not because I have any gyno symptoms.

There must be a certain e2 level after which 20-40 mg tamoxifen a day won't be able to prevent gyno. Even when I'm on tamoxifen, I should still experience the side effects you mentioned. When I get these side effects (or others like acne), then I will start using AIs.

What about this, guys:

Can someone tell me what to do now? I have tamoxifen and anastrozole. If I get an e2 level of 300 pmol/L, can I go with tamoxifen only, without using anastrozole?

Is 300 pmol/L potent enough to cause gyno, and if yes, will using only tamoxifen (20-40 mg a day) be enough to prevent gyno from 300 pmol/L, which is high but not extremely high, right? Answer this question, please, because it's the most important for me.

 

[RoidRage69]

My understanding is its better to use aromasin over tamoxifen because tamoxifen lowers IGF levels in the blood.

 

[s.gentz]

I'm on tamoxifen anyway. Currently, I take 20 mg a day, and I'm doing it preventively, not because I have any gyno symptoms.

There must be a certain e2 level after which 20-40 mg tamoxifen a day won't be able to prevent gyno. Even when I'm on tamoxifen, I should still experience the side effects you mentioned. When I get these side effects (or others like acne), then I will start using AIs.

What about this, guys:

Tamoxifen is selective to breast tissue. So even with high estrogen you are still blocking the receptor at the breast tissue. As was mentioned multiple times, everything you are asking is person dependent. Test and estrogen follow the same path. One goes up and the other will follow. Will it be linear? Who knows. All you can do is try and see.

On another note, people are spending time answering your questions. The least you could do is post a log of the cycle you are running. Give back a little.

 

[Npcclassicphysique champ]

I did a blood test and the results are the following:

Testosterone: 85.70 nmol/L (reference range: 8.64 - 29.00)
Estradiol: 153.00pmol/L (reference range: 28.0 - 156.0)

This corresponds to about 2300-2400 ng/dL (testosterone).

The results are good and I can say they exceeded my expectations. The free testosterone is also at a good level.

Despite being almost at the end of the reference range, I don't have any e2 side effects at all, not even slight water retention. Literally nothing.

These are the results I got from 250 mg testosterone a week.

What I want now is to increase the dose to 400 mg a week, which, if it follows a linear increase, will increase my e2 level well above the reference range, possibly up to 300 pmol/L.

Can someone tell me what to do now? I have tamoxifen and anastrozole. If I get an e2 level of 300 pmol/L, can I go with tamoxifen only, without using anastrozole?

Is 300 pmol/L potent enough to cause gyno, and if yes, will using only tamoxifen (20-40 mg a day) be enough to prevent gyno from 300 pmol/L, which is high but not extremely high, right? Answer this question, please, because it's the most important for me.

Also, I heard I need a proportional testosterone:estrogen ratio. That means, if my testosterone is high, my e2 should also be high. Is this true? So, according to this, if I have a T level that exceeds a specific level in terms of ng/dL, my e2 being within normal range will actually be harmful. Did I understand it correctly? If yes, what is that specific level in terms of ng/dL?

stay with aromasin and nolvadex bro

 

[stevesmi]

With a testosterone level that is that high I guarantee you that you should start your AI soon because your estrogen will continue to rise

 

[Mobster]

You are at an all time high (with zero E2 issues), for a matter or weeks, and want to go higher. No

 

[ceo]

Bros So you're gonna start your log or what

 

[ROIDDERS]

your blood work will constantly change it doesn't just stay the same

 

[chesty]

highly recommend you get on something now before the problem starts

 

[Ulter]

you can either take a chance and do nothing or you can be the safe side

 

[StevenDarwinMD]

This thread/post was reviewed by our Medical Review board.

 

[e2]

you also need to be taking your support supplements

 

[2Thick]

side effects will build up and Domino as a cycle goes on

 

[Vadim Fedorov]

I'm glad things are going good so far what kind of results are you getting

 

[Wootoom]

please post up a lot so we can track your progress properly