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NOT a log..... But..... test update

Lawyerguy1

Growing Brother
Ok, it’s not a log but it’s at least some info.

My last and recent post (look it up) was b/c I am on MD prescribed gel for TRT, but I also order extra on my own and take it in a blast/cruise fashion along with the occasional anavar/sarm cycle. I was in the middle of this a couple weeks ago only to discover my MD needs new bloodwork to renew my prescription.

And so the question: How long to leave off of the extra “blast” of gel before getting the bloodwork for my doc? Keep in mind, the gels are daily and actual simple testosterone, and so a very short half-life.

My thought was to simply take only prescribed amounts for 8 days and then blood test and I got support for this, but there was also a suggestion to take nothing at all for a week. I went with Door Number One, thinking that taking a short half-life gel as prescribed, my levels should still fall to within a “normal” looking range. Well, I did, and they did. These results were after me going back to simply (appropriately) prescribed amounts of gel. The doc of course ordered all kinds of bloodwork, but here are pics of some results. After first being on a blast of gel for quite a while and then taking only prescribed amounts for 8 days here’s where I ended up at, just so you know. I do also take stuff to help keep estrogen in line while on these higher amounts, and this recent testing also shows I’ve been doing a nice job of it.

I will add some info to this. I know gel gets a bad rap, and I can understand that, but hear me out a bit. It is very successful in terms of an actual TRT program, and there are likely also advantages. With most forms of testosterone injections you’re taking a substance that has a very long half life, which is why injections are anywhere from every week (at the shortest) to every 3 weeks (at the longest). You CAN take daily injections of short half life testosterone but then it’s a pain in the ass (see what I did there? 😊 ) daily injection. The advantage of the longer chain/longer half life forms is convenience, you inject only every so often. The disadvantage is that they are harder to dial in/adjust on short notice and you can’t get the natural daily ebb and flow of higher/lower testosterone like your body would have if it was simply producing its own and in its natural rhythm. Daily injections and/or daily gel will bring you into an acceptable daily range while still maintaining a normal daily high/low much like your body is supposed to have. This is due to the short half life.

But, now here’s where some magic can happen. . . The other bad rap on gel is that, comparatively, there is a lot of T in the gel in comparison to how much your body actually absorbs through the skin. Gel is “effective” but skin absorption is not the greatest transport vehicle in the world.

What if I told you that you can change this? Yes. . . you can, and very effectively. And there are many studies involving transdermal absorption of testosterone which shows that what I am saying is true. DMSO. Look it up. It is cheap, it is safe, it is easy. DMSO is a solvent liquid that is very, very common in veterinary medicine for decades and is becoming more and more common medically in more recent years. As a solvent, it is capable of carrying small molecules through the skin barrier like a red hot knife cutting through butter. It is used in veterinary medicine to make topical medications tremendously more effective than if they were applied without DMSO. It is used in people, medically, for other types of things, but skin is skin whether you are a horse getting a medication rub or you are a person getting a medication rub.

Studies that involve combining testosterone gel with DMSO show that transdermal absorption of T can be 4 times higher than using gel alone. So there you have it. Not only can DMSO be used to make prescribed amounts of gel that much more effective, if you are using gel in a blast type fashion you can have your body absorbing the equivalent of cycle levels of testosterone, all without needles at all, and while still using short half life testosterone which will allow quick dial of levels in if you test frequently or if you simply want more of a natural ebb and flow of daily T levels. And yeah, I can provide real medical study cites in terms of not only safety but also testosterone absorption.
 

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I like to see guys experimenting like this and getting blood work up
that's the thing blood work never lies
I can remember back in the 90s and early 2000s guys with argue things without any scientific backing and they would bully others into their point of views so it's good to see guys like you proving something with actual blood work
 
Ok, it’s not a log but it’s at least some info.

My last and recent post (look it up) was b/c I am on MD prescribed gel for TRT, but I also order extra on my own and take it in a blast/cruise fashion along with the occasional anavar/sarm cycle. I was in the middle of this a couple weeks ago only to discover my MD needs new bloodwork to renew my prescription.

And so the question: How long to leave off of the extra “blast” of gel before getting the bloodwork for my doc? Keep in mind, the gels are daily and actual simple testosterone, and so a very short half-life.

My thought was to simply take only prescribed amounts for 8 days and then blood test and I got support for this, but there was also a suggestion to take nothing at all for a week. I went with Door Number One, thinking that taking a short half-life gel as prescribed, my levels should still fall to within a “normal” looking range. Well, I did, and they did. These results were after me going back to simply (appropriately) prescribed amounts of gel. The doc of course ordered all kinds of bloodwork, but here are pics of some results. After first being on a blast of gel for quite a while and then taking only prescribed amounts for 8 days here’s where I ended up at, just so you know. I do also take stuff to help keep estrogen in line while on these higher amounts, and this recent testing also shows I’ve been doing a nice job of it.

I will add some info to this. I know gel gets a bad rap, and I can understand that, but hear me out a bit. It is very successful in terms of an actual TRT program, and there are likely also advantages. With most forms of testosterone injections you’re taking a substance that has a very long half life, which is why injections are anywhere from every week (at the shortest) to every 3 weeks (at the longest). You CAN take daily injections of short half life testosterone but then it’s a pain in the ass (see what I did there? 😊 ) daily injection. The advantage of the longer chain/longer half life forms is convenience, you inject only every so often. The disadvantage is that they are harder to dial in/adjust on short notice and you can’t get the natural daily ebb and flow of higher/lower testosterone like your body would have if it was simply producing its own and in its natural rhythm. Daily injections and/or daily gel will bring you into an acceptable daily range while still maintaining a normal daily high/low much like your body is supposed to have. This is due to the short half life.

But, now here’s where some magic can happen. . . The other bad rap on gel is that, comparatively, there is a lot of T in the gel in comparison to how much your body actually absorbs through the skin. Gel is “effective” but skin absorption is not the greatest transport vehicle in the world.

What if I told you that you can change this? Yes. . . you can, and very effectively. And there are many studies involving transdermal absorption of testosterone which shows that what I am saying is true. DMSO. Look it up. It is cheap, it is safe, it is easy. DMSO is a solvent liquid that is very, very common in veterinary medicine for decades and is becoming more and more common medically in more recent years. As a solvent, it is capable of carrying small molecules through the skin barrier like a red hot knife cutting through butter. It is used in veterinary medicine to make topical medications tremendously more effective than if they were applied without DMSO. It is used in people, medically, for other types of things, but skin is skin whether you are a horse getting a medication rub or you are a person getting a medication rub.

Studies that involve combining testosterone gel with DMSO show that transdermal absorption of T can be 4 times higher than using gel alone. So there you have it. Not only can DMSO be used to make prescribed amounts of gel that much more effective, if you are using gel in a blast type fashion you can have your body absorbing the equivalent of cycle levels of testosterone, all without needles at all, and while still using short half life testosterone which will allow quick dial of levels in if you test frequently or if you simply want more of a natural ebb and flow of daily T levels. And yeah, I can provide real medical study cites in terms of not only safety but also testosterone absorption.
@Lawyerguy1 how long between gel and tests? hard to say. Really I dont know much about you except your TRT.

I read your other thread and yea I see what you mean:
https://www.evolutionary.org/forums/threads/hrt-bloodwork-coming-up.98472/

but really here, the conversation is really off, transdermal testosterone, ok it works, and? its not for actual muscle building. You wont get that much transdermal for the goals most guys have on this forum. If pure TRT HRT sure transdermal could work but you wont get no gains from trt transdermal test dose.

Also I still dont get why you're here for many years and refuse to share LOG with us.
 
So... a product to boost test... boosts test?
Simply increases transdermal absorption rates, so yes. Not just of T, of many substances. There are verifiable studies, including testosterone specific ones. From a medical standpoint it’s actually quite interesting.
 
Simply increases transdermal absorption rates, so yes. Not just of T, of many substances. There are verifiable studies, including testosterone specific ones. From a medical standpoint it’s actually quite interesting.
I meant the TRT gel. But DMSO was being used by guys in the 80's to 2000's. The whole 'finaplex' kits (Cattle tren conversion). As I'm sure you'll appreciate the great and vast majority of members inject and or use orals. I'd also add a potential warning.

Thus: If I was doing X at (using a gel) a blob a day eqv to 60mg a day or similar I'd be careful not to lose track of that by using DMSO same as OTC meds and piparin/grapefuit. Of course, as in your example, if I did regular bloods I'd have an idea of what's going on.

Another thought: why didn't big pharma use DMSO? Cos you can also absorb any contaminants. And once you apply a gel to skin your, in essence, wide open.
 
I meant the TRT gel. But DMSO was being used by guys in the 80's to 2000's. The whole 'finaplex' kits (Cattle tren conversion). As I'm sure you'll appreciate the great and vast majority of members inject and or use orals. I'd also add a potential warning.

Thus: If I was doing X at (using a gel) a blob a day eqv to 60mg a day or similar I'd be careful not to lose track of that by using DMSO same as OTC meds and piparin/grapefuit. Of course, as in your example, if I did regular bloods I'd have an idea of what's going on.

Another thought: why didn't big pharma use DMSO? Cos you can also absorb any contaminants. And once you apply a gel to skin your, in essence, wide open.

I meant the TRT gel. But DMSO was being used by guys in the 80's to 2000's. The whole 'finaplex' kits (Cattle tren conversion). As I'm sure you'll appreciate the great and vast majority of members inject and or use orals. I'd also add a potential warning.

Thus: If I was doing X at (using a gel) a blob a day eqv to 60mg a day or similar I'd be careful not to lose track of that by using DMSO same as OTC meds and piparin/grapefuit. Of course, as in your example, if I did regular bloods I'd have an idea of what's going on.

Another thought: why didn't big pharma use DMSO? Cos you can also absorb any contaminants. And once you apply a gel to skin your, in essence, wide open.
Unless I’m mistaken, finaplex (trenbolone acetate) is a cattle steroid but is still intramuscular, correct?

You are correct correct about needing to be careful about skin contaminants though, DMSO should be applied to clean and dry skin because it will carry whatever is on the skin across the skin barrier. Not literally everything though. For instance, one study was whether forms of insulin could be applied topically. That would have been a gold mine. They can't, even with making the skin permeable with DMSO it just didn't work due to molecule size. Would you want to rub gasoline on you and then apply DMSO? Hell no. With simple steroid molecules though it is effective. Up to 4 times greater absorbtion, there are specific studies. With veterinary medicine, frankly some of the more common uses involve DMSO and corticosteroids. In the same respect skin permeability is not permanent, there is about a 15 minute window after application.

In terms of pharmacy companies, there are a lot of reasons, financial. The average cost to bring a drug from rrsrach studies to trials and market approval is just under a billion to almost 2 billion dollars (from Congressional Budget Office studies). Just because you CAN use DMSO doesn't mean it is cost effective if you've already spent your money developing a pill, which pill is easier than rubbing it all over your body. Etc, etc, etc. There actually are a lot of medical uses for DMSO though if you dig into it.
 
Bros you got a lot of good information to share
much respect for you being not another dumb Meathead
 
Unless I’m mistaken, finaplex (trenbolone acetate) is a cattle steroid but is still intramuscular, correct?

You are correct correct about needing to be careful about skin contaminants though, DMSO should be applied to clean and dry skin because it will carry whatever is on the skin across the skin barrier. Not literally everything though. For instance, one study was whether forms of insulin could be applied topically. That would have been a gold mine. They can't, even with making the skin permeable with DMSO it just didn't work due to molecule size. Would you want to rub gasoline on you and then apply DMSO? Hell no. With simple steroid molecules though it is effective. Up to 4 times greater absorbtion, there are specific studies. With veterinary medicine, frankly some of the more common uses involve DMSO and corticosteroids. In the same respect skin permeability is not permanent, there is about a 15 minute window after application.

In terms of pharmacy companies, there are a lot of reasons, financial. The average cost to bring a drug from rrsrach studies to trials and market approval is just under a billion to almost 2 billion dollars (from Congressional Budget Office studies). Just because you CAN use DMSO doesn't mean it is cost effective if you've already spent your money developing a pill, which pill is easier than rubbing it all over your body. Etc, etc, etc. There actually are a lot of medical uses for DMSO though if you dig into it.
They come in pellets hence the kits and a need to dissolve them etc etc. Pointless now as you can just inject Tren A.

People still experiment, often as not, needlessly. I've seen a recent post here about how much of an injectable is actually utilized vs injected (typically 60% IIRC). That's more of an issue, for reasons I stated earlier, with topical applications. Just cos it works doesn't mean it's a good idea. Let me give you one fucked up example:

I heard this story... dunno if it's 100%. Fella is a former and very recent alcoholic. He's in a program where the meds he's on to keep him off mean any oral consumption make him violently ill. So, cos he's desperate for a drink he has a willing GF stick a tube up his ass and pour vodka in. The issue is absorption is WAY higher and a LOT faster that way than via the usual route. Dies as he gets a massive hit. It's a variation of this one: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243473/

So you can do it and it's usually safe but why...
 
I think also it doesn't make any sense for Pharma to produce things are not going to make a profit on
that could be a reason
 
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Unless I’m mistaken, finaplex (trenbolone acetate) is a cattle steroid but is still intramuscular, correct?

You are correct correct about needing to be careful about skin contaminants though, DMSO should be applied to clean and dry skin because it will carry whatever is on the skin across the skin barrier. Not literally everything though. For instance, one study was whether forms of insulin could be applied topically. That would have been a gold mine. They can't, even with making the skin permeable with DMSO it just didn't work due to molecule size. Would you want to rub gasoline on you and then apply DMSO? Hell no. With simple steroid molecules though it is effective. Up to 4 times greater absorbtion, there are specific studies. With veterinary medicine, frankly some of the more common uses involve DMSO and corticosteroids. In the same respect skin permeability is not permanent, there is about a 15 minute window after application.

In terms of pharmacy companies, there are a lot of reasons, financial. The average cost to bring a drug from rrsrach studies to trials and market approval is just under a billion to almost 2 billion dollars (from Congressional Budget Office studies). Just because you CAN use DMSO doesn't mean it is cost effective if you've already spent your money developing a pill, which pill is easier than rubbing it all over your body. Etc, etc, etc. There actually are a lot of medical uses for DMSO though if you dig into it.
I've addressed that multiple times on podcasts when referring to high dose AAS (400mg per ml and up). It's 99% BS. They can just charge more if 400mg and up was 'better' and have a LOT of stats (literally millions of users) via patient use to see whether it's more or less effective.

Ditto why of the arguably 120 or so actual AAS patents and the same large numbers of sarms, peptides, etc we only see a fraction used and, often as not, many don't come to market. The money will have been spent but better options and applications were more effective again for the intended medical use. GW is one such example

I also recall work on oral applications for diabetes treatments and even GH. The GH one worked but the amount per dose was fkin tiny so you'd have to consume loads which took time vs a quick pin and done
 
a pretty cool stuff
I like threads like this keep them coming
 
I think that everybody is going to be a little different
some people will like using orals and some people will like using injectables
 
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