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Won't injecting testosterone at the end of each dose's half-life cause accumulation of testosterone in the body?

GoldenPlague

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The half-life and the active half-life of testosterone enanthate are 4-5 days and 10 days.

The half-life is what marks the time needed for 50% to be used by the body.

The active half-life is what marks the time needed for 100% to be used by the body.

I was told I need to inject each 3.5 or 4.5 days, not once in a week or each 10 days, in order to maintain stable testosterone levels and avoid so-called hormonal roller coaster.

If I always inject a new dose before exogenous testosterone is fully cleared of my system, won't this lead to an accumulation of testosterone, which will far exceeds any testosterone level I want to maintain? For example, if I start with a dose that corresponds to 1,000 ng/dL, wouldn't injecting before the substance is fully cleared of my system eventually lead to a level of 50,000, if I wait long enough?

I don't understand how there won't be an ever growing testosterone accumulation, if I always inject before the substance is fully cleared of my system.
 
At saturation the blood plasma levels will hit peak for that particular dose,once at peak you are pretty much stabilised as it’s always clearing the system just as it is always being cleaved off the ester.the injection frequency mostly recommended,(not by endos or doctors)at the half life is to prevent peaks and troughs or atleast keep them to a minimum.
 
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The half-life and the active half-life of testosterone enanthate are 4-5 days and 10 days.

The half-life is what marks the time needed for 50% to be used by the body.

The active half-life is what marks the time needed for 100% to be used by the body.

I was told I need to inject each 3.5 or 4.5 days, not once in a week or each 10 days, in order to maintain stable testosterone levels and avoid so-called hormonal roller coaster.

If I always inject a new dose before exogenous testosterone is fully cleared of my system, won't this lead to an accumulation of testosterone, which will far exceeds any testosterone level I want to maintain? For example, if I start with a dose that corresponds to 1,000 ng/dL, wouldn't injecting before the substance is fully cleared of my system eventually lead to a level of 50,000, if I wait long enough?

I don't understand how there won't be an ever growing testosterone accumulation, if I always inject before the substance is fully cleared of my system.
I'll address 1 point. The hormonal rollercoster idea.

It's kinda silly. Natural test levels vary through the day never mind the week. For example it's one of the hormones which wakes you up in the morning and why many 'suffer' with a 'morning glory' (aka an erection). It varies when you hit puberty and so on. So having it go up and down a little (and still at the upper end even on a 'low day') is mimicking nature. You do not grow constantly, eat non-stop or so on.

I'd also question this whole 'feel of being on'. If it was meaningful you'd notice it within an hour of the first injection. I've yet to see that claimed. There is SOME support for those with naturally low levels (doesn't apply to you as we know) who go on TRT and just p[lain feel better, more manly etc. There's also, as I have pointed out to others, this idea of focusing on 'how you feel' on test vs the reason of taking test to get strong, add muscle and so on.

It's also the reason why some micro-dose (pointless too). Ask those that do support this to show that they benefited with actual results above the usual method. And finally, although we do not use them for medical reasons, look at what each one was meant for.

Finally look at what you're taking any specific AAS for. If the half life is an issue (shouldn't be) pick Test Cyp. Also I've seen multiple timescales of half lives given for all AAS - just muddies the water again and again, we're not using it for medical reasons which is why short, medium and half lives were created.
 
Natural test levels vary through the day never mind the week. For example it's one of the hormones which wakes you up in the morning and why many 'suffer' with a 'morning glory' (aka an erection). It varies when you hit puberty and so on. So having it go up and down a little (and still at the upper end even on a 'low day') is mimicking nature. You do not grow constantly, eat non-stop or so on.
Variations through the day happen only when the testosterone is natural. When you inject the same dose each time, your testosterone levels stay stable and static.
I'd also question this whole 'feel of being on'. If it was meaningful you'd notice it within an hour of the first injection. I've yet to see that claimed. There is SOME support for those with naturally low levels (doesn't apply to you as we know) who go on TRT and just p[lain feel better, more manly etc.
I actually have low testosterone. As my blood test showed, my testosterone level stands at 600 ng/dL, which it bottom low. Anything below the super physiological levels is low.

Yeah, I'm planning to go on a permanent cycle, starting with a TRT dose just to see how the body reacts. Later, I will add compounds to the cycle.

When I'm on cycle, I'm in a TRT dose (or a higher testosterone, which depends on what I want) and additional compounds. When I'm off-cycle, I'm just in a TRT dose. But I don't think a PCT is a good idea.

Another problem I want to solve is my low DHT levels and androgenic activity. Judging by some thing, I have low DHT.
It's also the reason why some micro-dose (pointless too). Ask those that do support this to show that they benefited with actual results above the usual method. And finally, although we do not use them for medical reasons, look at what each one was meant for.
I didn't understand what you mean.

What micro-dose?
Finally look at what you're taking any specific AAS for. If the half life is an issue (shouldn't be) pick Test Cyp. Also I've seen multiple timescales of half lives given for all AAS - just muddies the water again and again, we're not using it for medical reasons which is why short, medium and half lives were created.
I want to start with a TRT dose of testosterone enanthate. I have chosen enanthate, because I prefer its half-life over the half-life of other testosterone esters that have a too long or too short half-life.

3.5 or 4.5 days is good enough to not be too often. Injecting too often can cause muscle fibrosis.

I want to start a TRT dose to see how the body reacts and measure my testosterone-to-esteogen conversion rate and aromatase activity. If things go well, later I will add more compounds, maybe.

Currently, I'm trying to understand what is a TRT dose that corresponds to 600-800 ng/dL, because I don't want to go to a very high level at the very beginning. Could it be 80 or 100 or 150 mg a week? 🤔
At saturation the blood plasma levels will hit peak for that particular dose,once at peak you are pretty much stabilised as it’s always clearing the system just as it is always being cleaved off the ester.the injection frequency mostly recommended,(not by endos or doctors)at the half life is to prevent peaks and troughs or atleast keep them to a minimum.
I think I understand, but can you, please, use some math and numbers to make it more clear?
 
steroids have esters attached to them to give them a slow release, as you inject them more build up in your system until you get to a point (around 5x the half life) where as much are clearing as getting put in, that is when your levels stabilize.. then when you stop injecting it takes time for those esters to clear out .. this is why when people use sustanon for example they say "oh i am still gaining 5 weeks after i stopped".. no actually there are still esters floating leftover since sustanon has a super long half life deca ester as part of the blend. its the same reason doctors don't prescribe test prop for trt and rather a long ester type of testosterone

unless they are steroids without those like test suspension or tren no ester etc.

You aren't listening to the podcast because I've explained this concept many times on there and it would save you a big headache to go and take the time to listen to the podcast where I explain exactly this
 
Microdosing (we have a search function you could use to look stuff up) is the idea of small frequent (daily) injections to 'keep levels stable'. It's over thinking. No one who does it will ever win the MrO while I have a working ass hole

You are far more likely to get what you keep calling fibrosis if you was to keep pinning in the same place. If you'd done ANY research you'll see we recommend rotating injecting sites.

You are now stating that ''Variations through the day happen only when the testosterone is natural. When you inject the same dose each time, your testosterone levels stay stable and static.'' Really. Didn't you start this thread by suggesting this can't happen or that the half life makes it impossible? Wasn't that literally the point of the thread?

Use some kind of logic. Let's say you've just injected 300mg of whatever. As soon as it's in the system it'll start to be metabolized (broken down), used or absorbed etc etc. Stevesmi already said in another thread that the ideas of not all of it being available for use is over thinking. Sufficient to say SOME will. It's unlikely that have constant blood tests to monitor testosterone levels but imagine if you could. IF so you'd see levels drop from whatever to whatever slowly but surely. 300mg of the one you suggested, Test E, would be (based on 4 days as given) circa 150mg 4 days later. Now you could jab on day 3 (so 450mg+) or day 4 (450mg for sure right?). You could wait for it to totally clear (40 odd days - but still detectable in a drug test) but you'd be suppressed and any left up to that point would be doing next to f'all benefits wise before pinning again and so on. We also know that those who cycle it by pinning their chosen amount (say a very sensible 250mg 2x a week) have NEVER had blood tests showing levels that have built up to anything worth a mention. Never mind 50,000ng or whatever it was you said earlier. NOT ONCE. Not for PED use nor medical use. And there's zero need to study this. Same logic applies to ANY other meds.

One reason to take advice as given and not need to know EVERYTHING (heck I don't nor do you) is advice given from those with 2 or more brain cells and who can explain themselves comes from (as we have stated on more than a few recent podcast) KNOWING what works for the majority. Based on YEARS of experience and 100's if not 10's of thousands of users getting similar outcomes.

You'll NEVER (certainly not as far as I'm concerned as it'd require a HUGE shift in PED usage and perception) see proper science and studies of the useful kind for PEDs due to current moral and ethical guidelines.
 
Variations through the day happen only when the testosterone is natural. When you inject the same dose each time, your testosterone levels stay stable and static.

I actually have low testosterone. As my blood test showed, my testosterone level stands at 600 ng/dL, which it bottom low. Anything below the super physiological levels is low.

Yeah, I'm planning to go on a permanent cycle, starting with a TRT dose just to see how the body reacts. Later, I will add compounds to the cycle.

When I'm on cycle, I'm in a TRT dose (or a higher testosterone, which depends on what I want) and additional compounds. When I'm off-cycle, I'm just in a TRT dose. But I don't think a PCT is a good idea.

Another problem I want to solve is my low DHT levels and androgenic activity. Judging by some thing, I have low DHT.

I didn't understand what you mean.

What micro-dose?

I want to start with a TRT dose of testosterone enanthate. I have chosen enanthate, because I prefer its half-life over the half-life of other testosterone esters that have a too long or too short half-life.

3.5 or 4.5 days is good enough to not be too often. Injecting too often can cause muscle fibrosis.

I want to start a TRT dose to see how the body reacts and measure my testosterone-to-esteogen conversion rate and aromatase activity. If things go well, later I will add more compounds, maybe.

Currently, I'm trying to understand what is a TRT dose that corresponds to 600-800 ng/dL, because I don't want to go to a very high level at the very beginning. Could it be 80 or 100 or 150 mg a week? 🤔

I think I understand, but can you, please, use some math and numbers to make it more clear?
Almost,you will still have slight variations.even with daily dosing.the more frequent pinning the lesser the variations.even at peak saturation,still variation.
 
Almost,you will still have slight variations.even with daily dosing.the more frequent pinning the lesser the variations.even at peak saturation,still variation.
But of no great consequence. Not one of the (probably over thinking anal types) micro-dosed mob are monsters. And there's been TONS of muscle added to those who jab (using Test E as an example) 2x a week.

It might be a subject for a debate but a boring one. The question being 'does it happen vs does it matter'? I say nope.

And, as I've pointed out in threads were a member is debating the frequency of pinning... if it's an issue just change the ester lol

Let's be honest if a lab ever formulated an PED (the volume containing enough mg would be an issue of course - maybe we'd need to jab all over the body to get around it) that lasted the length of the cycle I'd be all over it for one. Day 1... pinned myself 12 times.... 8 weeks later boom! It's that or hormone pellets under the skin
 
steroids have esters attached to them to give them a slow release, as you inject them more build up in your system until you get to a point (around 5x the half life) where as much are clearing as getting put in, that is when your levels stabilize.. then when you stop injecting it takes time for those esters to clear out .. this is why when people use sustanon for example they say "oh i am still gaining 5 weeks after i stopped".. no actually there are still esters floating leftover since sustanon has a super long half life deca ester as part of the blend. its the same reason doctors don't prescribe test prop for trt and rather a long ester type of testosterone

unless they are steroids without those like test suspension or tren no ester etc.

You aren't listening to the podcast because I've explained this concept many times on there and it would save you a big headache to go and take the time to listen to the podcast where I explain exactly this
Okay.
Can you give me an estimation of how much and how often should testosterone enanthate be injected to maintain a testosterone level of about 600-900 ng/dL?

If the dose is 100 mg a week or 2x50 mg a week, when will the accumulation (build up) of testosterone in the body stop? I don't want my testosterone levels to exceed the upper natural limit for the first 3 months of the experiment.
 
Can you give me an estimation of how much and how often should testosterone enanthate be injected to maintain a testosterone level of about 600-900 ng/dL?
150mg/wk puts me around 850-950. Everyone is different but that would be a good starting point. I would inject 2x per week.
If the dose is 100 mg a week or 2x50 mg a week, when will the accumulation (build up) of testosterone in the body stop? I don't want my testosterone levels to exceed the upper natural limit for the first 3 months of the experiment.
No, once you reach steady state after 4-5 weeks your levels will stay where they are. It takes time to build up in your blood.
 
150mg/wk puts me around 850-950. Everyone is different but that would be a good starting point. I would inject 2x per week.
I will start with a dose of 100 mg a week.

I have read that since it all depends on individuals metabolism, a specific testosterone dose will give a different ng/dL level to different people. What I'm trying to calculate right now is if a dose of 100 mg a week is high enough to cause high estrogen issues if I don't use aromatase inhibitors and/or tamoxifen. I don't want to use aromatase inhibitors at the beginning, because I want to know at what dose the effects of aromatization before problematic. If I use aromatase inhibitors, I will ever know that.

Is it known what is the maximum (highest) ng/dL value the best metabolism can produce out of a single milligram of synthetic testosterone? If I know the value, I will know what dose exactly to use.

I don't have the most potent metabolism, but knowing the highest ng/dL value that can be produced out of a single milligram or a specific dose of testosterone can be very helpful for me. For example, if the highest testosterone level ever recorded by scientific studies, from 100 mg testosterone a week, is, for example, 800 ng/dL, I will know that whatever level 100 mg give me, it will be lower than 800 ng/dL. That way I will better coordinate the steroids cycle I'm planning.
No, once you reach steady state after 4-5 weeks your levels will stay where they are. It takes time to build up in your blood.
Won't testosterone levels be affected immediately, with natural testosterone production being shut down immediately once exogenous testosterone is introduced?

I thought saturation happens at the end of the active half-life of the ester, when the substance is fully absorbed.

Why will the steady state be achieved after a month, not after 1 week? I still can't understand it.

So, if I inject a testosterone dose that corresponds to 600 ng/dL, which is my current natural testosterone level, and the dose has an active half-life of 7 days, won't my natural testosterone be fully shut down and replaced with the synthetic testosterone after 7 days, when the steady star will be achieved?

I can't understand the math here...
 
After pinning any ester, you will get a peak, which will then slowly go down until you dose again. So no levels are not static when injecting test. You can go to steroid plotter sites and view how this works.

And I explained before that even if you are natty your test levels fluctuate during the day. Your testes pulse out testosterone at different times of the day. So levels go up and down. They are not static.

If you are going to dose daily, I would recommend subq injections. As daily IM dosing will require a lot of different injection sites and you will end up with more scar tissue in the muscles pinned.
 
150mg/wk puts me around 850-950. Everyone is different but that would be a good starting point. I would inject 2x per week.
I forgot to ask one more thing. Do you remember what was your natural testosterone level before you started a TRT dose corresponding to 850-950 ng/dL? Is your current testosterone level higher than your natural testosterone level you had before you started TRT?
 
After pinning any ester, you will get a peak, which will then slowly go down until you dose again.
Yes, I know this. What I'm trying to figure out is what dose should I start with in order for the peak to NOT reach a too high level where the effects of aromatization before problematic.
 
Yes, I know this. What I'm trying to figure out is what dose should I start with in order for the peak to NOT reach a too high level where the effects of aromatization before problematic.
you start an AI from day 1

its scary that you are this detailed with this stuff.

are you this detailed when it comes to what you eat, the air you breathe, your sleeping habits, your training? because all that is more important then calculating what day steroid esters peak etc

its like a smoker, drinker and druggy who buys organic food. makes no sense. if you are gonna be this detailed then be consistent otherwise it makes no sense to make the effort.
 
Yes, I know this. What I'm trying to figure out is what dose should I start with in order for the peak to NOT reach a too high level where the effects of aromatization before problematic.
Everyone responds differently to test due to the fact everyone metabolises it differently.

You won't know until you start. No one can give you a definite answer on this. Everyone also aromatises at different rates.

Also know one can give you a level of estrogen in which it becomes problematic. As everyone responds differently to different estrogen levels.

I know guys who can have estrogen levels in the hundreds and get no symptoms of high estrogen. I also know guys who start getting bad estrogen sides at 100 or less.
 
But of no great consequence. Not one of the (probably over thinking anal types) micro-dosed mob are monsters. And there's been TONS of muscle added to those who jab (using Test E as an example) 2x a week.

It might be a subject for a debate but a boring one. The question being 'does it happen vs does it matter'? I say nope.

And, as I've pointed out in threads were a member is debating the frequency of pinning... if it's an issue just change the ester lol

Let's be honest if a lab ever formulated an PED (the volume containing enough mg would be an issue of course - maybe we'd need to jab all over the body to get around it) that lasted the length of the cycle I'd be all over it for one. Day 1... pinned myself 12 times.... 8 weeks later boom! It's that or hormone pellets under the skin
I agree with you.on sane train of thought there.your right,of no great consequence,and no it doesn’t matter in the grand scheme of it all.
 
When it is trt and even my first cycle I just did M/F injections everything was fine only reason this upcoming cycle is going into a 3 day split M/W/F is because I'm running multiple compounds and I like the ability to inject less of each conpound with each injection and building up to the full mg amounts over a 3 day spread instead of all at once, I like smaller injections less headache.

As far trt goes x2 a week smaller injections is perfectly fine and low dose AI from the start and then bloods get done 3-6 weeks after first pin to see where u stand and how u feel etc.
 
But of no great consequence. Not one of the (probably over thinking anal types) micro-dosed mob are monsters. And there's been TONS of muscle added to those who jab (using Test E as an example) 2x a week.

It might be a subject for a debate but a boring one. The question being 'does it happen vs does it matter'? I say nope.

And, as I've pointed out in threads were a member is debating the frequency of pinning... if it's an issue just change the ester lol

Let's be honest if a lab ever formulated an PED (the volume containing enough mg would be an issue of course - maybe we'd need to jab all over the body to get around it) that lasted the length of the cycle I'd be all over it for one. Day 1... pinned myself 12 times.... 8 weeks later boom! It's that or hormone pellets under the skin
Though I know a competitor here that does micro dose to combat aromatase,says it works for him and has no need for ai.
 
When it is trt and even my first cycle I just did M/F injections everything was fine only reason this upcoming cycle is going into a 3 day split M/W/F is because I'm running multiple compounds and I like the ability to inject less of each conpound with each injection and building up to the full mg amounts over a 3 day spread instead of all at once, I like smaller injections less headache.

As far trt goes x2 a week smaller injections is perfectly fine and low dose AI from the start and then bloods get done 3-6 weeks after first pin to see where u stand and how u feel etc.
As far as trt goes dont low dose AI just because.its not necessary,estrogen is not the enemy.
 
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