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Anabolicum (LGD-4033) Profile

Anablicum (LGD-4033) is a selective androgen receptor modulator (SARM), discovered by Ligand Pharmaceuticals Inc and perfected by SARMS1. LGD-4033 binds to the androgen receptor of muscle and bone selectively, exhibiting similar effects as testosterone, with only partial agonist activity on the prostate. It was developed as a way to treat diseases or conditions associated with muscle and bone deterioration. The advantage a SARM like LGD has over testosterone is the difference in activity it has on the body outside of muscle and bone.

anabolicum lgd-4033

Fig 1. Anabolicum (LGD-4033) Chemical Structure

Table of Contents


Anabolicum (LGD) has a significant effect on building lean muscle mass, strengthening bone and muscle, and it even has potential to help with healing. This is the most anabolic of SARMS, but, just like its cousins andarine and mk-2866, it binds very strongly to the androgen receptor. However, it favors the receptors in your muscle and bone, causing anabolic and anti-catabolic effects. In addition, it has a significant effect in preventing bone degeneration, and it has even proven to strengthen bones with minimized risk of typical androgenic problems like prostate enlargement, hair loss, etc.

In one study, male rats were castrated and left untreated for 14 days to allow for muscle and prostate to atrophy. These rats were then treated with Anabolicum (LGD-4033) after 14 days and showed potent activity in the skeletal muscle, but very weak activity in the prostate despite higher concentrations being found there. Another study, conducted by Ligand over a 28 day period, showed that increased muscle mass in female rats was related to an increase in the muscle fiber cross sectional diameter due to LGD use.

How can Anabolicum help me?

Anabolicum (LGD), like other popular SARMS, is very versatile and has a list of benefits no matter the goal of the user. Whether it's lean muscle mass, maintenance of your hard earned gains during a cutting cycle, or bridging the gap between steroid cycles, LGD-4033 can be a very beneficial tool. Studies suggest that this SARM will lend therapeutic benefit to many testosterone deficiency conditions. In fact, it's not unheard of to hear of improvements in joint pain or nagging injuries after starting a course of Anabolicum (LGD), much like its cousin Ostarine (MK-2866). In addition, LGD can increase strength, vascularity, and fat loss while bulking, and it can help during “recomposition” (recomp).

Reports of increased endurance is common and when stacked with Cardarine, and the level it increases will blow your socks off. Actually, LGD-4033 can be stacked quite well with any of the popular SARMS like ostarine (mk-2866), andarine and cardarine. In fact, it creates the perfect anabolic storm of lean muscle and fat loss when stacked with all 3 sarms, and it can be stacked safely, with minimal suppression.

Sample 8 week Anabolicum and Cardarine cycle

Week Anabolicum Cardarine HCGenerate N2Guard
1 10mgs/ED 20mgs/ED  - -
2 10mgs/ED 20mgs/ED  - 5caps/day
3 10mgs/ED 20mgs/ED  - 5caps/day
4 10mgs/ED 20mgs/ED 5caps/day 5caps/day
5 10mgs/ED 20mgs/ED 5caps/day 5caps/day
6 10mgs/ED 20mgs/ED 5caps/day 5caps/day
7 10mgs/ED 20mgs/ED 5caps/day 5caps/day
8 10mgs/ED 20mgs/ED 5caps/day 5caps/day

Side Effects

Anabolicum (LGD-4033) has virtually no side effects. With no significant activity in the prostate, and no liver toxicity whatsoever, this SARM does cause dose related hormone suppression. A slight decrease in total and free testosterone, as well as SHBG has been displayed with LGD, but neither LH nor FSH showed any decrease whatsoever. This means that after a cycle of anabolicum, you would need to do a full PCT to make sure you return to a healthy hormone balance. However, the fact that LH and FSH remain un-suppressed during administration of LGD, with make the natural hormone recover process should be quite easy. Also, you don't need to use an aromatase inhibitor like aromasin with LGD because it does not aromatize into estrogen.

Doses and Half-life

Anabolicum (LGD) is most commonly recommended at 5-10mg per day with once daily dosing schedule. The half-life of LGD is between 24-36hrs. It has been found to be well tolerated at up to 22mg/day in people.

Anabolicum vs LGD-4033

Anabolicum is the SARMS1 version of LGD-4033, which is stronger and better dosed than other LGD products on the market. Anabolicum is very potent and gives a lot more fat loss benefits than other lgd brands.


Anabolicum (LGD-4033) is unarguably the strongest SARM on the market today as far as anabolic power. It adds extra muscle building power to a cutting cycle, strength and size to a bulking cycle, and resilience for the endurance athlete. Used by itself or stacked with one or more other compounds, LGD demands recognition in the world of health, fitness, and bodybuilding.

BUY Anabolicum (LGD-4033) @ SARMS1.COM


BUY Anabolicum (LGD-4033) @ SARMS1.COM


Want to read about Anabolicum (LGD) on our forums? check out these threads:


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Jack Steel is a former NPC champion 2 local shows 1st place and 1 national show top 5 placement. He has an ACE personal training certifications and he's working to get his ISSA certification in 2021-2022. He is in school for a Masters in Medical Science.

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