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Metribolone, also called methyltrienolone, is a potent oral anabolic steroid that was originally developed in the 1960's to treat advanced breast cancer.  However, it was quickly pulled from the market because of its harsh side effects on the body, especially the liver.  Therefore, today it is used in research only.

Just like with most steroids, bodybuilders and athletes have experimented with this steroid since then, but due to its harshness and rarity, it's not popular at all.

Metribolone ampule

Fig 1. Metribolone ampule

Table of Contents


Metribolone is best known for being the steroid that caused 11 members of the Greek weightlifting team, and 4 members of their track and field team, to test positive ahead of the 2008 Beijing Olympic Games.  As a result, their weightlifting coach, Christos Lakovou, was suspended for his role in the scandal.


Perhaps, the only good news is that metribolone does not aromatize or convert into estrogen.  Yet, it is extremely hepatotoxic, and it could be comparable to stacking 2 or 3 of the harshest oral steroids at the same time.  In fact, studies have shown that the experimental rats developed organ cancer when given this steroid at abusive levels.  Obviously, we can presume that this steroid has a 17-alpha methyl group attachment, which will lead to tremendous strain on the liver.

Furthermore, metribolone is also a 19nor steroid (just like trenbolone or deca durabolin), and it has the ability to bind equally well in all tissues.  Hence, it is a great choice in universities studying androgen receptors.  As a matter of fact, it has been used since the 70's for research in animals because it is so resistant to metabolism, meaning it doesn't interfere with experimental results.  Interestingly, clinical research on humans is no longer an option due to its dangers.

Comparisons to oral trenbolone

A lot of people on forums will compare metribolone to oral trenbolone, and online steroid 'gurus' will claim that metribolone is the "most powerful steroid ever."  Are they right?

If you take a look at the structure, the first difference is that oral trenbolone is not 17-aa, while metribolone is methylated in a big way.  Moreover, on paper metribolone may appear to be hundreds of times more powerful than straight testosterone, but things on paper can be misleading; in fact, those who used metribolone say that it is milder than oral trenbolone, yet it is much more toxic because of the liver strain that occurs.

Metribolone chemicalstructure

Fig 2. Metribolone chemical structure

Side Effects

As mentioned, metribolone does not aromatize into estrogen, but this can be a tricky issue.  For instance, Anadrol is another oral steroid that does not aromatize, but it still binds with estrogen.  In the meantime, metribolone will bind to progesterone receptors, as it is a progestin 19nor compound.  Thus, even though there is no aromatization to estrogen, you can still end up with progestin based gynecomastia (bitch tits) anyway.

Additionally, due to its strength, metribolone causes such androgenic sides as aggression, acne, and male pattern baldness.  If that weren't enough, there are also the common steroid related issues, which are heart strain and suppression.

For women it will cause pronounced virilization symptoms, so female athletes should avoid metribolone at all cost.

Finally, liver damage can easily occur with metribolone, not just because it is 17-aa, but because it is highly resistant to hepatic metabolism.  Consequently, if you choose to run this compound, you need a good liver supporting supplement, and you should get blood work done both during and after usage.  Remember, it is easily the most liver toxic steroid in existence!  Therefore, a strong support supplement is crucial, and I recommend using a double dosage of N2Guard.


Metribolone is not a product that should be used, so I do not recommend athletes or bodybuilders use it.  Those who are foolish enough to try it will run 0.5 milligrams (mgs) to 5mgs per day split dose.  Regarding the cycle duration, you should not exceed 3 to 4 weeks of use.

User Results

Metribolone might seem like the best thing ever because on paper it's so strong, but this is misleading.  As already mentioned above, it is actually milder than oral trenbolone, yet more toxic on the liver.  Those that have managed to find it say they were disappointed with the results; though, this might be partially a result of using underdosed or bunk products.  My belief is that the amount of metribolone you would have to run and the length of cycle you would need in order to see results would be counter productive to your health in the first place, so it is best to use safer alternatives.


Want to read about Metribolone on our forums? check out these threads:

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Written by
Steve Smi (Also known as Steve Smith), has over 12 years of experience in the bodybuilding and fitness industry. He's the co-Host of the popular Evolutionary Radio Podcast - over 500,000 listens! He has been a personal trainer and writer for the last 10 years with over 1000 articles written. He's been a moderator on forums for over 10 years. Steve holds the following certifications and records: NASM Personal Trainer NASM Fitness Nutrition Specialist Florida Local Powerlifting champion Top writer for 2019 Fitness rated

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