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Nolvadex (Tamoxifen citrate), a non-steroidal antiestrogen for oral administration, is commonly used by athletes as a post cycle therapy drug and to reduce the formation of excess estrogens that can lead to gynecomastia.

Fig 1. Tamoxifen Chemical Structure
In the world of bodybuilding, Nolvadex has been a very controversial drug. It's a constant battle to see guys who are pro-nolva and anti-nolva, but in the end tamoxifen is always going to be one of the go-to tools in gynecomastia treatment and PCT.
The reason guys might be anti-nolvadex is they feel there are better options with both SERMS and AIs to combat both estrogenic side effects and gynecomastia problems (bitch tits). However, none of the alternatives work as well as nolvadex in tissue specific gynecomastia treatment. Nolva is able to target the estrogen receptors in the breast tissue to reduce gynecomastia at the source (right around the nipple area).
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References
- Tamoxifen ("Nolvadex"): a review
- Tamoxifen citrate therapy in male infertility
- Tamoxifen
- A phase II study Nolvadex: tamoxifen citrate in the treatment of advanced prostatic adenocarcinoma
- Tamoxifen in men: a review of adverse events
- Oral tamoxifen citrate treatment is more effective in normogonadotropic patients who have follicle-stimulating hormone levels within the lower half of normal