I'm not sure because I don't, nor have I ever, injected B12. I do know that some people bodies cannot "process" or "use" B12 efficiently. I only know this because my wife has a genetic mutation that causes her body to not efficiently use B12. We discovered this during genetic testingHow often should one person use b12 injections per month ? Is one shot a . month enough or does it last for longer ? What do you think ?
How often should one person use b12 injections per month ? Is one shot a . month enough or does it last for longer ? What do you think ?
I'm not sure because I don't, nor have I ever, injected B12. I do know that some people bodies cannot "process" or "use" B12 efficiently. I only know this because my wife has a genetic mutation that causes her body to not efficiently use B12. We discovered this during genetic testing
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Yea. It is pretty interesting. I dont remember all the specifics on it. We discovered the mutation while having genetic testing done while trying to figure out how to treat her Lyme disease. Her first LLMD (lyme literate medical doctor) had her injecting B12 twice a week. His overall protocol produced no positive changes and lots of wasted money so we moved on. Her second LLMD suggested the genetic testing along with a completely different treatment regimen. We followed through with his treatment and suggest testing and that's when we discovered this mutation. He informed us that injecting B12 twice a week was a waste because it was way too much. He cut her back to one EO week. After the mutation was discovered her took her off the B12 completely. We also discovered that, being just about 100% Norwegian, she is genetically predisposed to chronic Lyme. It was pretty interesting.....Really? That's very interesting, sub_squoch.
"...my wife has a genetic mutation that causes her body to not efficiently use B12." How does that manifest itself in her body, and does this condition affect the assimilation of her naturally-occurring B-12?
Yea. It is pretty interesting. I dont remember all the specifics on it. We discovered the mutation while having genetic testing done while trying to figure out how to treat her Lyme disease. Her first LLMD (lyme literate medical doctor) had her injecting B12 twice a week. His overall protocol produced no positive changes and lots of wasted money so we moved on. Her second LLMD suggested the genetic testing along with a completely different treatment regimen. We followed through with his treatment and suggest testing and that's when we discovered this mutation. He informed us that injecting B12 twice a week was a waste because it was way too much. He cut her back to one EO week. After the mutation was discovered her took her off the B12 completely. We also discovered that, being just about 100% Norwegian, she is genetically predisposed to chronic Lyme. It was pretty interesting.....
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I had to quiz my wife quick before she walked out the door for her wedding so I could at least get you a little more (accurate) info. So it's called a mthfr gene mutation. She is double homozygous which means she has both gene mutations for mthfr. Apparently its actually quite common. So it's my understanding, based on what she told me as she ran out the door, that her body doesnt produce enough of it's own B12. Its basically a B12 deficiency. It also makes it hard for her body to breakdown histamines which is why she easily gets hives. Because of this she was also diagnosed with mass cell activation. So if she takes an oral synthetic B12 it just passes through her body unused apparently. B12 in shot form is more effective for her but still iant processed/used greatly. That gene mutation prevents the B12 from being usable by producing a particular enzyme that "blocks" the B12. For her personally, her natural B12 production is low but that isnt the case with everyone that had this.So does that mean that her body's inability to properly assimilate B-12 exacerbates her tick-borne Lyme disease?
I had to quiz my wife quick before she walked out the door for her wedding so I could at least get you a little more (accurate) info. So it's called a mthfr gene mutation. She is double homozygous which means she has both gene mutations for mthfr. Apparently its actually quite common. So it's my understanding, based on what she told me as she ran out the door, that her body doesnt produce enough of it's own B12. Its basically a B12 deficiency. It also makes it hard for her body to breakdown histamines which is why she easily gets hives. Because of this she was also diagnosed with mass cell activation. So if she takes an oral synthetic B12 it just passes through her body unused apparently. B12 in shot form is more effective for her but still iant processed/used greatly. That gene mutation prevents the B12 from being usable by producing a particular enzyme that "blocks" the B12. For her personally, her natural B12 production is low but that isnt the case with everyone that had this.
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I had to quiz my wife quick before she walked out the door for her wedding...[/QUOTE}
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I had to quiz my wife quick before she walked out the door for her wedding...
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She's a caterer, right?
That is as interesting as what it is distressing to know that your wife iw compelled to endure all of that. Please tell her that I wish her the best.
And does this condition worsen the symptoms of her Lyme disease?
One last thing, sub_squoch. Will you please explain the precise meaning of the following statement?
Not sure how said mutation actually affects her Lyme complications. Prior to getting Lyme we didnt know she had this mutation. She did know she was B12 deficient but didnt know why. Yes, Lyme is hell. Almost took her from us a few times the first year. Shes been symptomatic for 2.5 years now. We have it under control but things aren't the same for her.....or any of our immediate family. Her "good" days are not like they used to be. Shes about 50/50 good/bad days. Shes tough as hell. She continues to impress me with her resilience. Getting her diet in check and incorporating weight training has helped her tremendously. She is a photographer - mainly weddings but some boudoir alsoI had to quiz my wife quick before she walked out the door for her wedding...[/QUOTE}
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She's a caterer, right?
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