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As promised in an earlier post.

I'm 5 weeks done as of this blood test (still early for EQ to be fully saturated)

Dose is 200eq / 385 test as of this snapshot

I'm usually a high aromatizer, my E2 at this test level would have otherwise been 600+

HCT is unchanged (47)

Both are smooth and leave absolutely no PIP.
 

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theradbrad said:
As promised in an earlier post.

I'm 5 weeks done as of this blood test (still early for EQ to be fully saturated)

Dose is 200eq / 385 test as of this snapshot

I'm usually a high aromatizer, my E2 at this test level would have otherwise been 600+

HCT is unchanged (47)

Both are smooth and leave absolutely no PIP.
Click to expand...
My 2 absolute favs from @R&Dpharma Test & Eq 🙏

Though a big heads up brother, thats an immunoassay test you had done for you e2. Already i can guarantee you that you oestradiol levels will be much lower as you need to test e2 with lcms bloods when running eq.

At the 5 week mark and further saturation to still come into effect there is a high chance your on the road to nuking your estrogen and believe me you dont want to get to that point lol.

Lcms tests are critical with equipoise, and the brothers eq has some venom in it to lol its fucking strong.
 
Allupfromhere said:
My 2 absolute favs from @R&Dpharma Test & Eq 🙏

Though a big heads up brother, thats an immunoassay test you had done for you e2. Already i can guarantee you that you oestradiol levels will be much lower as you need to test e2 with lcms bloods when running eq.

At the 5 week mark and further saturation to still come into effect there is a high chance your on the road to nuking your estrogen and believe me you dont want to get to that point lol.

Lcms tests are critical with equipoise, and the brothers eq has some venom in it to lol its fucking strong.
Click to expand...
Lcms probably isn’t necessary in Australia

Most labs use Siemens ATEL for their immunoassay which has minimal estrone cross reactivity (<5%)

At 5 weeks in he’s probably 85% of the way to steady state so should be fine
 
Allupfromhere said:
My 2 absolute favs from @R&Dpharma Test & Eq 🙏

Though a big heads up brother, thats an immunoassay test you had done for you e2. Already i can guarantee you that you oestradiol levels will be much lower as you need to test e2 with lcms bloods when running eq.

At the 5 week mark and further saturation to still come into effect there is a high chance your on the road to nuking your estrogen and believe me you dont want to get to that point lol.

Lcms tests are critical with equipoise, and the brothers eq has some venom in it to lol its fucking strong.
Click to expand...
Thanks for that bro ! You're absolutely right, first time running EQ so wasn't sure what to expect for myself

This 5 week test was just a cheapy quick rough guide of what's to come, real bloods will be done at week 8-9, but given the results + your thoughts and mine has given me the itch to up the test a bit expecting a bigger drop + also next test will be sensitive. I'll adjust dosing and post up the next set of sensitive bloods for you all to see again.

Either way, R&D is gun, great ⚙️ 👍🏼
 
Cominghard said:
Lcms probably isn’t necessary in Australia

Most labs use Siemens ATEL for their immunoassay which has minimal estrone cross reactivity (<5%)

At 5 weeks in he’s probably 85% of the way to steady state so should be fine
Click to expand...
What are you actually basing that 5% range off brother?

This is the same blood sample with lcms and siemens atel immunoassay with a 20% range difference
Screenshot_20260505_111809_Gallery.webp
Screenshot_20260505_111716_Gallery.webp
 
Allupfromhere said:
My 2 absolute favs from @R&Dpharma Test & Eq 🙏

Though a big heads up brother, thats an immunoassay test you had done for you e2. Already i can guarantee you that you oestradiol levels will be much lower as you need to test e2 with lcms bloods when running eq.

At the 5 week mark and further saturation to still come into effect there is a high chance your on the road to nuking your estrogen and believe me you dont want to get to that point lol.

Lcms tests are critical with equipoise, and the brothers eq has some venom in it to lol its fucking strong.
Click to expand...
Thanks for heads up bout getting lcms test as ill be getting bloods very soon running eq in my stack.
 
fingers86 said:
Thanks for heads up bout getting lcms test as ill be getting bloods very soon running eq in my stack.
Click to expand...
Anytime brother! Lcms def crucial with using eq. If you find you need to make corrections with whats reflected in the test results and get stuck reach out brother 🙏
 
theradbrad said:
As promised in an earlier post.

I'm 5 weeks done as of this blood test (still early for EQ to be fully saturated)

Dose is 200eq / 385 test as of this snapshot

I'm usually a high aromatizer, my E2 at this test level would have otherwise been 600+

HCT is unchanged (47)

Both are smooth and leave absolutely no PIP.
Click to expand...
good bloods :D clean results for Team R&D @R&Dpharma
would you consider starting a log? :D test/eq logs popular @theradbrad
 
@Kouta posted TD pics for Team R&D @R&Dpharma :D
https://www.evolutionary.org/forums/threads/reviews.103376/post-2067344
Kouta said:
Slightly delayed but I got around to it!

Touchdown of R&D’s most beautiful looking labeled products from the “buy and enter giveaway!” Communication was great, really easy to chat with and make an order. Little hiccup on postage so the man threw in an extra test e vial as an apology even after I insisted not to worry about it, man of his word and his status speaks for itself.

Great guy, great products and great service!

Let’s just take a minute and admire those stunning labels, my fucking god! 🤤🤤🤤
Click to expand...
img_0769-webp.228380
 
Allupfromhere said:
What are you actually basing that 5% range off brother?

This is the same blood sample with lcms and siemens atel immunoassay with a 20% range difference View attachment 225618View attachment 225620
Click to expand...
Other things can falsely inflate the immunoassay result (but not immunoassay) other than estrone/boldenone

Most particularly tren , some orals and nandrolones

But they’re also calibrated differently so no two different machines will provide same number for same sample, and all manufacturers use different referent standards

Even the same machine same plasma has a margin of error couple percent

Point is that directionally and relatively the boldenone will not throw the immunoassay off that much

Save your money imo especially if you have a baseline and are just tracking direction and magnitude of change
 
Cominghard said:
Other things can falsely inflate the immunoassay result (but not immunoassay) other than estrone/boldenone

Most particularly tren , some orals and nandrolones

But they’re also calibrated differently so no two different machines will provide same number for same sample, and all manufacturers use different referent standards

Even the same machine same plasma has a margin of error couple percent

Point is that directionally and relatively the boldenone will not throw the immunoassay off that much

Save your money imo especially if you have a baseline and are just tracking direction and magnitude of change
Click to expand...
Agree with the false inflation of tren with e2 and nandrolone more often with testosteron levels but have witnessed interference with e2 levels as well in some cases. However this wasnt the point being debated.

The point was that he nees lcms testing when using boldenone so he can limit the risk of crashing his oestradiol levels.

You mentioned that you dont believe its necessary as there would be less then a 5% interference of estrone cross activity.

I asked what studies or information your based your 5% claims of brother and provided you with bloods work using boldenone with both immunoassay and lcms clearly showing an almost 20% difference.

You still havent answered the question or shown any supportive information to your claim yet legend..
 
Allupfromhere said:
Agree with the false inflation of tren with e2 and nandrolone more often with testosteron levels but have witnessed interference with e2 levels as well in some cases. However this wasnt the point being debated.

The point was that he nees lcms testing when using boldenone so he can limit the risk of crashing his oestradiol levels.

You mentioned that you dont believe its necessary as there would be less then a 5% interference of estrone cross activity.

I asked what studies or information your based your 5% claims of brother and provided you with bloods work using boldenone with both immunoassay and lcms clearly showing an almost 20% difference.

You still havent answered the question or shown any supportive information to your claim yet legend..
Click to expand...
Allupfromhere said:
Agree with the false inflation of tren with e2 and nandrolone more often with testosteron levels but have witnessed interference with e2 levels as well in some cases. However this wasnt the point being debated.

The point was that he nees lcms testing when using boldenone so he can limit the risk of crashing his oestradiol levels.

You mentioned that you dont believe its necessary as there would be less then a 5% interference of estrone cross activity.

I asked what studies or information your based your 5% claims of brother and provided you with bloods work using boldenone with both immunoassay and lcms clearly showing an almost 20% difference.

You still havent answered the question or shown any supportive information to your claim yet legend..
Click to expand...
Think you’re misunderstanding the maths

If estrone cross reactivity is 5% it means that 400pmol/L of estrone will show up as 20pmol/L on an immunoassay estradiol test

Not that the estradiol results will differ by 5%
That will be a function of the relative estradiol/estrone levels, not to mention any other confounders as well

His results do not invalidate the claim

I don’t have access to the Siemens product insert right now but here for example is a public study showing Roche and Beckmann cross reactivity is 1-2%

https://pmc.ncbi.nlm.nih.gov/articles/PMC8859944/

So 5% is certainly very believable , maybe even too pessimistic
 
Cominghard said:
Think you’re misunderstanding the maths

If estrone cross reactivity is 5% it means that 400pmol/L of estrone will show up as 20pmol/L on an immunoassay estradiol test

Not that the estradiol results will differ by 5%
That will be a function of the relative estradiol/estrone levels, not to mention any other confounders as well

His results do not invalidate the claim

I don’t have access to the Siemens product insert right now but here for example is a public study showing Roche and Beckmann cross reactivity is 1-2%

https://pmc.ncbi.nlm.nih.gov/articles/PMC8859944/

So 5% is certainly very believable , maybe even too pessimistic
Click to expand...
Let me ask you this brother...

The blood work i showed you displays a difference in oestradiol levels of almost 20%.

18.5% to be exact.

To you genuinely feel the potential this difference can have on someone doesnt warrant the use of lcms testing when it comes to dialling in e2 levels?
 
Allupfromhere said:
Let me ask you this brother...

The blood work i showed you displays a difference in oestradiol levels of almost 20%.

18.5% to be exact.

To you genuinely feel the potential this difference can have on someone doesnt warrant the use of lcms testing when it comes to dialling in e2 levels?
Click to expand...
Because even two different immunoassays can show substantial variation between manufacturers , as they are calibrated differently

You can even see that the reference ranges for your two tests are totally different

The absolute number is therefore also irrelevant

In any case your values are not low on either test . So whether the “real” estradiol level is 150, 200 or 250 is completely irrelevant
Getting the lcms made no difference to your decision making in this case - your estrogen is just above the normal range on both tests

But it’s your money , spend it how you like I don’t care
 
Cominghard said:
The absolute number is therefore also irrelevant
Click to expand...
The absolute number is always relevant lol thats the whole point of conducting blood work, to see where particular levels are at.
Cominghard said:
In any case your values are not low on either test . So whether the “real” estradiol level is 150, 200 or 250 is completely irrelevant
Getting the lcms made no difference to your decision making in this case - your estrogen is just above the normal range on both tests
Click to expand...
Yeah but we weren’t debating whether those numbers were low or not brother. The whole point was to clearly show the difference lcms testing can have, and the potentially detrimental effects crashed e2 can cause in someone from inaccurate levels.

Cominghard said:
But it’s your money , spend it how you like I don’t care
Click to expand...
We're only chatting brother no need to get frustrated. But the price of lcms testing is less then a vial of test. Small price to pay to get things right when someone is willing to spend money on gear in the first place dont you think?

Anyway i can see you frustrated brother and i never set out to argue with ya so i dont want this to become something is never needed to be. Was more to give some points of view for readers in similar situations.

Enjoy your day legend.
 
Allupfromhere said:
The absolute number is always relevant lol thats the whole point of conducting blood work, to see where particular levels are at.

Yeah but we weren’t debating whether those numbers were low or not brother. The whole point was to clearly show the difference lcms testing can have, and the potentially detrimental effects crashed e2 can cause in someone from inaccurate levels.


We're only chatting brother no need to get frustrated. But the price of lcms testing is less then a vial of test. Small price to pay to get things right when someone is willing to spend money on gear in the first place dont you think?

Anyway i can see you frustrated brother and i never set out to argue with ya so i dont want this to become something is never needed to be. Was more to give some points of view for readers in similar situations.

Enjoy your day legend.
Click to expand...
Was a really good discussion for a while brother, I was learning quite a bit...shame it fell away 🩵
 
theJimJim said:
Cheers R&D
Bit of the golden nectar
View attachment 228629
Click to expand...
Ill have to add. This was sent out as we thought Auspost had lost the first package. Not on R&D at all. They replaced for free out of good will.
I couldn't have been more blown away. Great customer service.
 
Allupfromhere said:
The absolute number is always relevant lol thats the whole point of conducting blood work, to see where particular levels are at.

Yeah but we weren’t debating whether those numbers were low or not brother. The whole point was to clearly show the difference lcms testing can have, and the potentially detrimental effects crashed e2 can cause in someone from inaccurate levels.


We're only chatting brother no need to get frustrated. But the price of lcms testing is less then a vial of test. Small price to pay to get things right when someone is willing to spend money on gear in the first place dont you think?

Anyway i can see you frustrated brother and i never set out to argue with ya so i dont want this to become something is never needed to be. Was more to give some points of view for readers in similar situations.

Enjoy your day legend.
Click to expand...
There is no “truth” in medicine or in life generally (except mathematics )

One lcms machine will give a different absolute number compared to another from a different manufacturer


Yes , lcms is not susceptible to estrone cross reactivity .
But as you can see from the study I provided that estrone cross reactivity is almost negligible

The 18% difference between your two test results is NOT entirely or even mostly due to estrone .
It’s mostly due to the fact that they are two totally different machines from different manufacturers with different calibration


But even if the estrone contribution was the entire 18% , it made no practical difference to your decision making in any case - your estradiol is at an appropriate level on both tests

Therefore the lcms was clearly a waste of money


Also we all know that what estrogen level feels good is totally individual . One person will feel like a bloated mess at 250 with a limp dick and tits, while another feels great. One person will feel suicidal at 60, while another person won’t notice anything

So the only trick if you FEEL SYMPTOMS is working out if you are too low or too high as there is overlap between symptoms

Now, if the immunoassay had been borderline low , like 90 , then is there a case to check it with lcms ?
Maybe but wouldn’t you just base it off symptoms at that point?
You know from immunoasssay that you don’t have HIGH estrogen
And at worst your lcms is going to be a little bit lower but not like 40
If you have low estrogen symptoms it’s clear what you need to do
If you have no symptoms , then carry on

If the immunoassay estradiol was 50, then also getting the lcms is a waste of money - you are clearly too low regardless since immunoassay only ever OVERestimates not underestimates and it’s irrelevant whether you are really 50 or really 30

And what are you going to do get lcms on every set of bloods? Just once ?

You’d be better getting monthly immunoassays than 3 monthly lcms since you can track the change in values which is the real relevant information not the absolute as discussed above


Anyway I’ve provided the evidence , and explained my logic you do what you like
 
theJimJim said:
Ill have to add. This was sent out as we thought Auspost had lost the first package. Not on R&D at all. They replaced for free out of good will.
I couldn't have been more blown away. Great customer service.
Click to expand...
Amazing customer service.

Wouldn't expect anything less from one of the best in the business 👌
 
From the fkin man himself :love: 🙏 last package to arrive from the R&D giveaway. HAHA come full circle since R&D pharma was my first purchase since joining EVO fam aye HAHA. Received 4x Test E 250mg, 2x Tren A 100mg and 2x Tren E 200 total of 8 vials. Fk it looks amazing 😭. Thanks a lot brother. I still can't believe it man.
1778485213141.webp
 
Jintae said:
From the fkin man himself :love: 🙏 last package to arrive from the R&D giveaway. HAHA come full circle since R&D pharma was my first purchase since joining EVO fam aye HAHA. Received 4x Test E 250mg, 2x Tren A 100mg and 2x Tren E 200 total of 8 vials. Fk it looks amazing 😭. Thanks a lot brother. I still can't believe it man. View attachment 228644
Click to expand...
About to get juicy huge my man!
 
I should add I’m talking about eq only

Estrone cross reactivity is a solved problem because manufacturers needed to solve it for normal clinical purposes in women etc

Trenbolone cross reactivity is a different story and not something that manufacturers would bother to correct for since steroid abusers are not their core business and trenbolone is not naturally occurring

It may be a substantial confounder and you may need to do lcms for that I really don’t know
 
Cominghard said:
There is no “truth” in medicine or in life generally (except mathematics )

One lcms machine will give a different absolute number compared to another from a different manufacturer


Yes , lcms is not susceptible to estrone cross reactivity .
But as you can see from the study I provided that estrone cross reactivity is almost negligible

The 18% difference between your two test results is NOT entirely or even mostly due to estrone .
It’s mostly due to the fact that they are two totally different machines from different manufacturers with different calibration


But even if the estrone contribution was the entire 18% , it made no practical difference to your decision making in any case - your estradiol is at an appropriate level on both tests

Therefore the lcms was clearly a waste of money


Also we all know that what estrogen level feels good is totally individual . One person will feel like a bloated mess at 250 with a limp dick and tits, while another feels great. One person will feel suicidal at 60, while another person won’t notice anything

So the only trick if you FEEL SYMPTOMS is working out if you are too low or too high as there is overlap between symptoms

Now, if the immunoassay had been borderline low , like 90 , then is there a case to check it with lcms ?
Maybe but wouldn’t you just base it off symptoms at that point?
You know from immunoasssay that you don’t have HIGH estrogen
And at worst your lcms is going to be a little bit lower but not like 40
If you have low estrogen symptoms it’s clear what you need to do
If you have no symptoms , then carry on

If the immunoassay estradiol was 50, then also getting the lcms is a waste of money - you are clearly too low regardless since immunoassay only ever OVERestimates not underestimates and it’s irrelevant whether you are really 50 or really 30

And what are you going to do get lcms on every set of bloods? Just once ?

You’d be better getting monthly immunoassays than 3 monthly lcms since you can track the change in values which is the real relevant information not the absolute as discussed above


Anyway I’ve provided the evidence , and explained my logic you do what you like
Click to expand...
You’re still focusing purely on what is causing the variance between the two tests, when that’s not really the core point being discussed here brother.

The point is that lcms is objectively the gold standard methodology for e2 assessment. It is the most specific, the most reliable and the most accurate method we currently have available. That’s not really debatable.

Yes, different machines, calibration methods and manufacturers can create variance in absolute numbers. Nobody is denying that. But that argument still doesn’t somehow make immunoassay equally reliable for assessing estradiol in enhanced athletes, especially in scenarios where compounds are known to interfere with interpretation and symptom presentation.

You’re also heavily leaning on the “go by feel” argument, which only really works once someone actually understands how their own body responds to fluctuating estrogen levels.

A first time eq user does not have that reference point yet.

They don’t know what high e2 genuinely feels like for them,what crashed e2 genuinely feels like for them, how anxiety, lethargy, libido fluctuations, flatness, water retention or mood changes personally manifest.

To make things even harder, low and high estrogen symptoms can overlap massively.

That is exactly why obtaining the most accurate baseline picture possible matters in this particular circumstance.

You mentioned “at worst lcms will only be slightly lower, not 40,” yet the actual bloodwork posted literally showed a discrepancy of just over 40 between results. So clearly these variances can become clinically relevant depending on the context and individual response.

Now does every single person need lcms on every blood test forever?

No. I never said that.
But for someone, running eq for the first time, trying to establish their personal aromatisation profile, trying to correlate symptoms with actual serum levels, potentially making aromatisation inhibiting adjustments based on that data

…then yes, using the most accurate testing method available absolutely makes logical sense.

Because once you start making dose adjustments off inaccurate assumptions, that’s where people end up chasing their tail and crashing e2 unnecessarily.

And that’s really the key point here,
Lcms in this scenario is not about obsessing over numbers for the sake of numbers.

It’s about establishing a reliable reference point during an unknown variable.

Once someone understands how they personally respond, how their bloods trend, and how symptoms correlate over time, then sure, standard immunoassays can absolutely be useful for cheaper ongoing monitoring and trend tracking.

But when you are initially trying to paint the clearest possible picture of what is actually happening physiologically, accuracy matters.

Especially before someone starts manipulating hormones based on “feel” alone.
 
Allupfromhere said:
You’re still focusing purely on what is causing the variance between the two tests, when that’s not really the core point being discussed here brother.

The point is that lcms is objectively the gold standard methodology for e2 assessment. It is the most specific, the most reliable and the most accurate method we currently have available. That’s not really debatable.

Yes, different machines, calibration methods and manufacturers can create variance in absolute numbers. Nobody is denying that. But that argument still doesn’t somehow make immunoassay equally reliable for assessing estradiol in enhanced athletes, especially in scenarios where compounds are known to interfere with interpretation and symptom presentation.

You’re also heavily leaning on the “go by feel” argument, which only really works once someone actually understands how their own body responds to fluctuating estrogen levels.

A first time eq user does not have that reference point yet.

They don’t know what high e2 genuinely feels like for them,what crashed e2 genuinely feels like for them, how anxiety, lethargy, libido fluctuations, flatness, water retention or mood changes personally manifest.

To make things even harder, low and high estrogen symptoms can overlap massively.

That is exactly why obtaining the most accurate baseline picture possible matters in this particular circumstance.

You mentioned “at worst lcms will only be slightly lower, not 40,” yet the actual bloodwork posted literally showed a discrepancy of just over 40 between results. So clearly these variances can become clinically relevant depending on the context and individual response.

Now does every single person need lcms on every blood test forever?

No. I never said that.
But for someone, running eq for the first time, trying to establish their personal aromatisation profile, trying to correlate symptoms with actual serum levels, potentially making aromatisation inhibiting adjustments based on that data

…then yes, using the most accurate testing method available absolutely makes logical sense.

Because once you start making dose adjustments off inaccurate assumptions, that’s where people end up chasing their tail and crashing e2 unnecessarily.

And that’s really the key point here,
Lcms in this scenario is not about obsessing over numbers for the sake of numbers.

It’s about establishing a reliable reference point during an unknown variable.

Once someone understands how they personally respond, how their bloods trend, and how symptoms correlate over time, then sure, standard immunoassays can absolutely be useful for cheaper ongoing monitoring and trend tracking.

But when you are initially trying to paint the clearest possible picture of what is actually happening physiologically, accuracy matters.

Especially before someone starts manipulating hormones based on “feel” alone.
Click to expand...
No my argument is that eq and its estrone metabolites don’t make a meaningful difference to immunoassay estradiol results

The evidence I have presented supports my claim

Also it’s clear that on your last test getting the lcms changed nothing about your decision making

But everyone can make their own decisions depending on their level of confidence/anxiety and financial situation
 
Cominghard said:
No my argument is that eq and its estrone metabolites don’t make a meaningful difference to immunoassay estradiol results
Click to expand...
Let me dilute this then and try meet you in the middle.. Your saying it doesnt make a meaningful difference because you feel you only need to know if e2 is high or low and immunoassay can show you which side of the fence your sitting and thats good enough in your opinion?

Ok, in that sense if someone is happy with just a general idea of which side there e2 is leaning into, that makes sense.

Personally for me i want a little more accuracy, and from the fashion of peoples opinion on dialling in e2 the trend says the majority do too.

Cominghard said:
The evidence I have presented supports my claim
Click to expand...
supports the claim the aligns with your opinion on the level of accuracy you personally find acceptable.

Cominghard said:
Also it’s clear that on your last test getting the lcms changed nothing about your decision making
Click to expand...
well no it actually couldnt, because my decision to implement the doses that provided those results had to be made prior for those results to actually be obtained.

It didnt influence any further decision because i had hit the mark of where i wanted e2 to sit. Had the results reflect a number i wasnt happy with, i would have readjusted and then yes it would have.
Cominghard said:
But everyone can make their own decisions depending on their level of confidence/anxiety and financial situation
Click to expand...
Here is something we both clearly agree on🙏


This has been good, i think we have both brought points to the table that can give difference of perspective for someone deciding what level of accuracy they are happy with when dialling a compound like e2 in for the very first time.

🤝🙂
 
R&Dpharma said:
These prices are our standard non sale prices
followed by contact details and payment options as well as reviews if anyone purchasing from R&D has a positive or negative review please post it here were always looking to improve

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Tren E 200 - $70
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Mast E 200mg - $80
Mast p 100mg - $70
Equipoise 300mg - $90
Primo E 200mg - $130

Contact details
session
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threema
HMRS5YCD
new Feb 2026
https://www.evolutionary.org/forums...rd-price-list-and-reviews.100245/post-1965380

Payment Options
Bitcoin and cardless cash

UPDATED LIST October 2025
https://www.evolutionary.org/forums...rd-price-list-and-reviews.100245/post-1844991
Click to expand...
How do I make an order ?
 
Allupfromhere said:
Let me dilute this then and try meet you in the middle.. Your saying it doesnt make a meaningful difference because you feel you only need to know if e2 is high or low and immunoassay can show you which side of the fence your sitting and thats good enough in your opinion?

Ok, in that sense if someone is happy with just a general idea of which side there e2 is leaning into, that makes sense.

Personally for me i want a little more accuracy, and from the fashion of peoples opinion on dialling in e2 the trend says the majority do too.


supports the claim the aligns with your opinion on the level of accuracy you personally find acceptable.


well no it actually couldnt, because my decision to implement the doses that provided those results had to be made prior for those results to actually be obtained.

It didnt influence any further decision because i had hit the mark of where i wanted e2 to sit. Had the results reflect a number i wasnt happy with, i would have readjusted and then yes it would have.

Here is something we both clearly agree on🙏


This has been good, i think we have both brought points to the table that can give difference of perspective for someone deciding what level of accuracy they are happy with when dialling a compound like e2 in for the very first time.

🤝🙂
Click to expand...
No you have not understood

Estrone is not a significant confounder of modern immunoassays
1-2% is nothing, similar to overall margin of error

You (and maybe someone else?) then asked me then to explain why your two test values were 18% discrepant
I have done my best to explain the mathematics and medical science I hope you have some grasp now


Your lcms and immunoassay both produced similar and clinically acceptable results regardless . Had you not got the lcms you would still not have changed anything and you would not have been significantly mislead about your estrogen status

There is a very narrow set of values and clinical scenarios where getting lcms may have changed your interpretation of the results or changed your cycle .


If your values and clinical scenario end up falling in that narrow and unlikely band , you can always get lcms as a retest and you wait a couple of days extra at worst since immunoassay results come back so fast

You seem to enjoy the sense of security that the number gives you and that makes paying extra worth it for you , but for most people it’s a waste of money since it adds no USEFUL extra information 95% of the time (tren users excluded)

Are you getting lcms testosterone too ?
Why / why not
 
Cominghard said:
No you have not understood

Estrone is not a significant confounder of modern immunoassays
1-2% is nothing, similar to overall margin of error

You (and maybe someone else?) then asked me then to explain why your two test values were 18% discrepant
I have done my best to explain the mathematics and medical science I hope you have some grasp now


Your lcms and immunoassay both produced similar and clinically acceptable results regardless . Had you not got the lcms you would still not have changed anything and you would not have been significantly mislead about your estrogen status

There is a very narrow set of values and clinical scenarios where getting lcms may have changed your interpretation of the results or changed your cycle .


If your values and clinical scenario end up falling in that narrow and unlikely band , you can always get lcms as a retest and you wait a couple of days extra at worst since immunoassay results come back so fast

You seem to enjoy the sense of security that the number gives you and that makes paying extra worth it for you , but for most people it’s a waste of money since it adds no USEFUL extra information 95% of the time (tren users excluded)

Are you getting lcms testosterone too ?
Why / why not
Click to expand...
Brother I think the discussion is getting derailed here because the original point was never “does immunoassay give enough rough clinical direction?” It was specifically about what testing method makes the most sense for someone trying to accurately dial in e2 for the first time on eq.

You stated there is only a tiny difference between modern immunoassay and lcms due to estrone cross reactivity, around 1-2%, and I then showed bloodwork demonstrating an 18.5% discrepancy between the two methods. Regardless of the exact contribution estrone made to that difference, the reality is the discrepancy was still far larger than the “negligible” difference you originally claimed.

That was the seperate point being discussed.

Whether both results still landed within a “clinically acceptable” range afterward is a completely separate conversation and doesn’t invalidate the existence of the discrepancy itself.

For someone using eq for the first time and trying to understand exactly where theirEe2 is sitting, I personally think the more accurate methodology makes more sense. Especially when people are making decisions around ai use, symptom interpretation, and dose adjustment from those numbers.

You may personally feel immunoassay provides enough directional information for your comfort level, and that’s completely fine.

I, and clearly many others based on current trends, prefer the tighter accuracy lcms provides when trying to establish a more precise baseline.

That was always my point.


You seem to be heading down a pathway that makes it seem your having a different conversation to where this began and where i have tried to keep its focus lol.

As for lcms testing on testosterone i dont feel the need to UNLESS there is another compound involved that interferes with the accuracy im chasing.
 
Turbo_Dog_ said:
Thanks bro. I can't find my way around these forums 😂
Click to expand...
Thats all good brother, the last conversation has unnecessarily clogged up this thread so sorry if it created too much clutter.

Use code Allupfromhere10 for a discount with the bro @R&Dpharma
 
Jintae said:
From the fkin man himself :love: 🙏 last package to arrive from the R&D giveaway. HAHA come full circle since R&D pharma was my first purchase since joining EVO fam aye HAHA. Received 4x Test E 250mg, 2x Tren A 100mg and 2x Tren E 200 total of 8 vials. Fk it looks amazing 😭. Thanks a lot brother. I still can't believe it man. View attachment 228644
Click to expand...
Congrats jintae
 
Allupfromhere said:
Thats all good brother, the last conversation has unnecessarily clogged up this thread so sorry if it created too much clutter.

Use code Allupfromhere10 for a discount with the bro @R&Dpharma
Click to expand...
Happy to have this exchange of information here
 
@Panda22 posted TD pics for Team R&D @R&Dpharma in LOG :D
https://www.evolutionary.org/forums...-log-with-team-r-d-pharma.110538/post-2074709
Panda22 said:
Panda Build - Week Four 🐼

PEDs @R&Dpharma
  • 3iu HGH (AM)
  • GHK-CU 2.5mg
  • KPV 500mcg
  • MT2 250mcg (winter is coming)
  • Reta 2mg
  • L-Carnitine 600mg/1ml
  • Anavar (5mg, training days only, Starting week 4)
  • *BPC + TB as required
Supplements
  • Vital Support @RGSX
  • Fish oil (additional dose to vital support)
  • Zinc
  • Cinnamon
  • Magnesium glycinate
  • Collagen
  • HBCD Powder
  • EEAs
  • Psyllium Husk
  • Lysine
  • Vitamin C

Training focus

Tuesday:
Hip Thrust 4x8 130kg
RDL 3x6 85kg
BSS 3x8 32.5kg DB
Seated Ham Curl 3x8 60kg
Hip Abduction (standing machine) 3x12 100kg

Wednesday Upper B:
Flat DB Press 3x8 20kg DBs
Lat Raise 3x12 12kg
Pull Ups 4x5
Rear Delt (single arm cable) 3x10 10kg
Tricep Pushdown 3x10 26.5kg
Hammer Curl 3x10 12kg

Thursday:
Hip Thrust 3x8 110kg
*Landmine Curtsy Lunges 3x8 20kg plate
*Landmine Hack Squat 4x5 40kg plate
Walking Lunges 3x10 each leg 24kg DBs
Leg Extension 3x10 70kg
Lying Ham Curl 3x10 35kg
*alternative exercise due to hotel gym equipment

Saturday:
Hip Adductors 3x10 40kg
Hip Abductors (standing) 3x10 100kg
Landmine Lateral Lunge to Overhead Press 3x6 each side 10kg plate
Landmine step back lunge 3x6 each side 10kg plate
Landmine single leg hack squat 3x8 each side 20kg place

Sunday:
Barbell Cleans 3x3 50kg, 2x3 40kg *dropped back weight to correct my technique
Sled Push 6 laps 100kg (120-130kg total weight)
Sled Pull 6 laps 100kg (120-130kg total weight)

Nutrition

Carb cycling setup:
  • High days (lower sessions): 2350 kcal (P-140g C-300 F-50)
  • Moderate (upper/BJJ): 2150 kcal (P-140g C-240 F-55)
  • Low (rest days): 1950 kcal (P-135g C-170 F-55)

Water
Water intake is consistent at 5L/day with electrolytes (Hydralyte) every 1.25L

Feeling
This week was a travel week for me. I was able to move my first leg session to Monday as I flew out Tuesday Morning, the other sessions were done at the hotel gym so had to be slightly modified due to the equipment available to me. The hotel gym is decent enough so I can still get a lot of things done! I feel like I have travelling down now and don't lose any momentum or routine - I am sure I look crazy going through the airport security with all my meals, supplements, and powders to get me through the week!

I pushed the weight up on my leg days and tried some new movements with the landmine which was really cool! I can feel that now in my adductors! Sled weights also went up which was really painful but I got it done and managed to keep my time without being sick!

Sleep has been on track even with the travel and sleeping in a hotel bed - I think a lot of that is due to being able to hold my routine (food/exercise/sleep and wake times) and @RGSX sleep support!

Heres a few photos of the hotel gym DB's which are a weird weight, and my legs after sled pumps!

Also my touchdown top up from the one and only @R&Dpharma keeping my gains and recovery exactly where it needs to be!

Thanks for following along Evo Fam!

View attachment 232484View attachment 232485View attachment 232486View attachment 232487View attachment 232488View attachment 232489View attachment 232490


If you’re looking to maximise your results with R&D make sure to use Panda10 in your message to receive 10% off your order!
R&D PHARMA THREEMA: HMRS5YCD
Click to expand...
img_4336-webp.232490
 
✨✨ TOUCHDOWN ✨✨

I received my latest restock of @R&Dpharma goods - as always shipping was quick and easy and I got everything in time!
I am back on MT2 now that summer is gone and already I can see a pop in my skin tone, hoping this can hold all winter!

Thanks for the consistently epic work @R&Dpharma and team!

IMG_4336.webp
 
Panda22 said:
✨✨ TOUCHDOWN ✨✨

I received my latest restock of @R&Dpharma goods - as always shipping was quick and easy and I got everything in time!
I am back on MT2 now that summer is gone and already I can see a pop in my skin tone, hoping this can hold all winter!

Thanks for the consistently epic work @R&Dpharma and team!

View attachment 232526
Click to expand...
Epic touchdown sister 🩵
 
Panda22 said:
✨✨ TOUCHDOWN ✨✨

I received my latest restock of @R&Dpharma goods - as always shipping was quick and easy and I got everything in time!
I am back on MT2 now that summer is gone and already I can see a pop in my skin tone, hoping this can hold all winter!

Thanks for the consistently epic work @R&Dpharma and team!

View attachment 232526
Click to expand...
Beautiful TD :D
 
I am also waiting on an order from 3rd of may. I paid on the same day 3rd of may and messaged that I had sent the payment. Messaged a week later for an update and he said I hadnt paid even though I had. He asked for a tx id which I sent through. No reply so I again ask if they confirmed the payment and sent the order. He says that he did but even now I still havent gotten anything and when I asked for another update I just get ignored. If there is some delay or something then that is fine would just like some communication especially after I got jerked around with on the payment. I am messaging this session account.
1000003168.webp
 
Kytamuri91 said:
Hey so I did an order about 3 weeks ago now and I asked for tracking on the 10th day and since that time he is completely ignoring me and just leaving my messages on read. Is there any way around this?
Click to expand...

simpleesaucee said:
I am also waiting on an order from 3rd of may. I paid on the same day 3rd of may and messaged that I had sent the payment. Messaged a week later for an update and he said I hadnt paid even though I had. He asked for a tx id which I sent through. No reply so I again ask if they confirmed the payment and sent the order. He says that he did but even now I still havent gotten anything and when I asked for another update I just get ignored. If there is some delay or something then that is fine would just like some communication especially after I got jerked around with on the payment. I am messaging this session account.View attachment 233897
Click to expand...
Dm me brothers let me chase this up... the bro is away at the moment but orders are still being processed so let me see where the hiccup is and get you both sorted 👌
 
simpleesaucee said:
I am also waiting on an order from 3rd of may. I paid on the same day 3rd of may and messaged that I had sent the payment. Messaged a week later for an update and he said I hadnt paid even though I had. He asked for a tx id which I sent through. No reply so I again ask if they confirmed the payment and sent the order. He says that he did but even now I still havent gotten anything and when I asked for another update I just get ignored. If there is some delay or something then that is fine would just like some communication especially after I got jerked around with on the payment. I am messaging this session account.View attachment 233897
Click to expand...
You might have the wrong account mate I made an order last week and received it. Is that threema?
 
simpleesaucee said:
Nah its session. Im new to this sorta thing and just went with the first contact info I saw on the original post. Good to hear someones received their order recently. Allupfromhere is trying to help me hopefully get it sorted.
Click to expand...
Every time there is a comms issue with trusted vendors it normally comes back to app other than Threema. Should just ditch all the other apps from the forum.
 
Alchy said:
Touch down! Ordered on Saturday and came today (Thursday). Cheers for the quick and easy service
Click to expand...
Beautiful TD :D @Alchy what is your cycle plan?
 
Alchy said:
This is gonna be my first time hopping on the gear bro. Im just starting with 150mg/wk test c 2mg/wk reta for now and see how that goes.
Click to expand...
150mgs test is good self TRT, did you do bloods before? :D @Alchy
 
Alchy said:
Sure did! Came back all good. Any tips on when i should do my bloods again after jumping on trt?
Click to expand...
can you please share the bloods you have already? blur personal info

after jumping on 3 weeks in is a good time to test
 
Alchy said:
First pin starting next week my bro! I got a coach putting me on a plan too. 150mg trt wont be much of a difference would you say?
Click to expand...
who is your coach? :D @Alchy
150 trt could be a difference tbh but sports TRT 300mgs/week would be a big kick
 
Alchy said:
First pin starting next week my bro! I got a coach putting me on a plan too. 150mg trt wont be much of a difference would you say?
Click to expand...
Bro your natural bloods are really good, whats the reason you coach has to put you on 'trt'? Why not just run a cycle and come off? Or if your planning on staying on trt i feel you coach shouldnt be looking at a mg dose approach and should be looking more at targeting a specific testosterone level.

Whats your current situation legend? As in, age, have kids already?
 
@Popmusclez posted in LOG TDs for Team R&D @R&Dpharma

https://www.evolutionary.org/forums...eavyweight-growth-journal.106417/post-2086725
Popmusclez said:
Who doesn’t love delivery day 🔥

A massive thankyou as always to @R&Dpharma for taking care of me!

Little restock of:
Test e
EQ
GH
Novorapid
Lantus (this wasn’t for me it’s for my partner @_bubbles)

Deload has started today. Orders are only upper body training, no legs as we want to lift fatigue and inflammation (especially from the legs).

Once this week is up. Food will increase to around 4K and slin will go back in pre workout. T4 is being added back in aswell to help with any down regulation of thyroid function as GH is back in too (50mcg daily).

We’re in a good spot, let’s go 💪🏽
Click to expand...
img_7987-webp.239724
 
Markytee1 said:
300mg is way too much to be classed as sports trt, it's more of a small cycle. The difference in body composition will be massive.
Click to expand...
300mgs is the normal sports TRT dose actually :D thats why its called sports TRT @Markytee1 commonly used terminology
 
Alchy said:
First pin starting next week my bro! I got a coach putting me on a plan too. 150mg trt wont be much of a difference would you say?
Click to expand...

Brother sound like it’s your first time running gear, if your young and starting out, nothing wrong with just running 150mg pw and see how you feel. You can always titrate the dose up to 200-300mg

If you do run a cycle make sure you are on top of your food, rest and have a couple of fuck buddies on speed dial.
 
LevButlerov said:
300mgs is the normal sports TRT dose actually :D thats why its called sports TRT @Markytee1 commonly used terminology
Click to expand...
Not trying to be a smart arse but, trt dose are usually between 120mg-160mg per week, obviously its an individual dose, some might need even more than that, anything over that is classed as sports trt, to double your trt dose and call it sports trt? At what dose does a cycle start?
 
Markytee1 said:
Not trying to be a smart arse but, trt dose are usually between 120mg-160mg per week, obviously its an individual dose, some might need even more than that, anything over that is classed as sports trt, to double your trt dose and call it sports trt? At what dose does a cycle start?
Click to expand...
I always though sports trt was 150mg ish test + 100mg mast or primo 😅😅😅
 
whatupg1234 said:
I always though sports trt was 150mg ish test + 100mg mast or primo 😅😅😅
Click to expand...
sports TRT is usually 300mgs test :D bodybuilding TRT is 300mgs test + other gear
 
Markytee1 said:
Not trying to be a smart arse but, trt dose are usually between 120mg-160mg per week, obviously its an individual dose, some might need even more than that, anything over that is classed as sports trt, to double your trt dose and call it sports trt? At what dose does a cycle start?
Click to expand...
Fair question, I think there are general terms in the industry used in communities that are widely accepted due to anecdotal evidence, including bloods. So for the term Sports TRT its usually 300mgs of test, but this doesnt mean you have to absolutely do it, its more of a suggestion :D @Markytee1
 
whatupg1234 said:
I always though sports trt was 150mg ish test + 100mg mast or primo 😅😅😅
Click to expand...
Yeah, that works aswell, anything slightly over your trt dose either abit more test or low dose of another compound will be classed as sports trt, if you want to do sports trt + you can add Tren. 😀
Normal free Testosterone range according to imedical is between 200-600 pmol/L so a sports trt could be around 600- 800 pmol/L maybe upto 900 anything over that isnt sports trt.
 
LevButlerov said:
sports TRT is usually 300mgs test :D bodybuilding TRT is 300mgs test + other gear
Click to expand...

LevButlerov said:
sports TRT is usually 300mgs test :D bodybuilding TRT is 300mgs test + other gear
Click to expand...
If we’re realistic trt is a popular name for people who wanna use gear but think saying trt is more acceptable to the general public. Anything over 150mg a weak is just using gear. It shouldn’t be so taboo, if you’re using test just say I’m on test and if you don’t wanna talk about don’t tell anyone.
 
FATABO said:
If we’re realistic trt is a popular name for people who wanna use gear but think saying trt is more acceptable to the general public. Anything over 150mg a weak is just using gear. It shouldn’t be so taboo, if you’re using test just say I’m on test and if you don’t wanna talk about don’t tell anyone.
Click to expand...
Sure fair. I think its not just our term, Huberman was talking about sports TRT over 200 as well. And well said I think cycling should be more mainstream.
 
FATABO said:
If we’re realistic trt is a popular name for people who wanna use gear but think saying trt is more acceptable to the general public. Anything over 150mg a weak is just using gear. It shouldn’t be so taboo, if you’re using test just say I’m on test and if you don’t wanna talk about don’t tell anyone.
Click to expand...
150mg only puts me at 650/25 Test now had to bump it up to 175mg to get closer to 800/30 I get blood tests every 8 weeks on TRT

I used to get 1000/35 on 150mg so not sure whether it's my body getting used to it or raw quality has dropped this year?
 
Allupfromhere said:
Bro your natural bloods are really good, whats the reason you coach has to put you on 'trt'? Why not just run a cycle and come off? Or if your planning on staying on trt i feel you coach shouldnt be looking at a mg dose approach and should be looking more at targeting a specific testosterone level.

Whats your current situation legend? As in, age, have kids already?
Click to expand...
Thanks for the feedback bro. It was my choice to just do TRT as its my first time doing it. I'm currently 25 and have no kids. I honestly just want to reap the benefits of having higher test haha. I definitely wouldn't mind a cycle in the near future once I'm more knowledgable etc. The only thing i'm worried about is TRT is that you pretty much never hop off right? Would you say doing a few cycles in my prime years would be better than to just TRT right now? Any more tips would be greatly appreciated!
 
TechnoViking said:
150mg only puts me at 650/25 Test now had to bump it up to 175mg to get closer to 800/30 I get blood tests every 8 weeks on TRT

I used to get 1000/35 on 150mg so not sure whether it's my body getting used to it or raw quality has dropped this year?
Click to expand...
I was same when I first started on 150mg. Base line was 17 and 170. 200mg a week got me into the 1000s
 
Markytee1 said:
Not trying to be a smart arse but, trt dose are usually between 120mg-160mg per week, obviously its an individual dose, some might need even more than that, anything over that is classed as sports trt, to double your trt dose and call it sports trt? At what dose does a cycle start?
Click to expand...
Trt doses typically aim to get your levels to high end of natural range. So based on this i dont feel we can put a specific milligram dose as such to catagorise what we class as trt. Beyond this point as we breach into low superphysioligical this is what we generally see and make out to be a 'sports trt' dose.

Further beyond this point again as we find our levels well into the superphysiological levels like 2000+ free test, regardless of what people want to call this for comfort lol, your on and blasting 😂
Alchy said:
Thanks for the feedback bro. It was my choice to just do TRT as its my first time doing it. I'm currently 25 and have no kids. I honestly just want to reap the benefits of having higher test haha. I definitely wouldn't mind a cycle in the near future once I'm more knowledgable etc. The only thing i'm worried about is TRT is that you pretty much never hop off right? Would you say doing a few cycles in my prime years would be better than to just TRT right now? Any more tips would be greatly appreciated!
Click to expand...
Bro 25 no kids and your whole life ahead of you. If you must use gear this early i would mostly steer you in the direction of doing a single cycle a year at most. And trying to keep it no more then 16 weeks with compounds that arent super toxic to your health. At your age you should spend more time each year off cycle then on. 💙
 
FATABO said:
Didn’t do lms so normal reading was 185. I started at 300mg Eq and joints were sore so halved it but could probably drop it again to 75-100mg joints we’re getting sore at the end.
Click to expand...
at 75 your joints were sore?
 
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