Free radicals are molecules with an unbalanced negative charge looking to bond. Histones are positive charged molecules that wrap the base nucleotides in your DNA, and thus balancing the charge. Free radicals have a greater affinity for the histones and steal them from the base pairs. This leads the two negative charges base nucleotides to repel one another, and be blown out of the DNA strand which then closes up. This later leads to transcriptase encoding errors during replication since everything is done in chunks of 3 pairs, and now the strand count is misaligned. Antioxidants work by having an unbalanced positive charge and bonding with free radicals to bring balance, and prevent them from causing genetic damage. Curcumin does have antioxidant properties and turmeric is a good natural anti-inflammatory.