I love Jerry's channel and highly respect his opinions and views on training/drugs/life. That being said, I COULD NOT DISAGREE MORE. Drop sets are not for everyone but I find them to be extremely effective.
Jerry is basically arguing that: 1) drop sets over-tax your nervous system 2) it lessens the work done by muscles because you decrease weight 3) you are unnecessarily increasing muscular endurance and not hypertrophy 4) less 'continuous' time under tension 5) anecdotal evidence that it doesn't work.
By far the most compelling of these arguments is that drop sets can over tax your nervous system leading to overtraining. This is certainly true for some people as well as newbies to the weight room but this phenomena is not limited to drop sets. Anytime you dedicate an entire workout to a single body part you can over-tax your nervous system even if you are only using straight sets, because you are still doing 16+ sets on a specific muscle group. BUT this is why people with 6 day splits wait a week before training the same muscle group again. There is simply more to recover from. Case in point look at Arnold's old school 2 workouts a day, 2 day splits, training 6 days a week. A mere mortal would have the same over training issues Jerry described even if they used straight sets.
Let me ask you guys something, why do we use spotters during traditional sets? Aside from safety, spotters help us squeeze the last couple reps out at the end of a set when our muscles are failing. But guess what, that's exactly the same effect as lowering (dropping) the weight! It seems like Jerry's true philosophy is against training to failure in general for the reasons listed above.
Regarding the rest of his points: Apparently I have fundamental differences with Jerry about the principles of hypertrophy. I've always believed in lifting the MUSCLE and not the weight. Getting a good pump. Maximizing the amount of time my muscles are under tension with as much weight as possible. High weight (relatively)/high reps. To me the best way to do this is using drop sets!
I don't use drop sets for every lift and every muscle group. I tend to use pyramid sets for heavier compound lifts. Isolation work is where drop sets really shine, because of the limitations of how much weight you can use. Therefore one has to compensate, make the lift harder, by lifting heavy for some good reps, dropping the weight and keeping the train rolling.
The reason this works is simply the total 'work' done by a muscle group. Total weight * distance moved * time under tension. Literally the basics of progressive overload for hypertrophy. Here's a comment from Jerry on this video: "study my ass, show me someone gain size faster than me doing drop sets. i bet i blow their doors off training my way. studies are great but in the gym the only thing that piece of paper is good for is wiping your ass." Apparently he doesn't give a shit about studies, well I don't give a shit about his anecdotal evidence.
Again, drop sets aren't going to be the best for everyone but I would wager that a large portion of bodybuilders especially the non-nattys would benefit from them.