Hey EVO family, I have been lurking for a while and have had the pleasure of talking with a few members. I have found EVO to have a great community that I would love to get support on my current situation from, as I’m still so new to this all.
Background:
27 years old, 184cm, started at 107.5kg now at 98.8kg, down 8.7kg in 9 weeks. Active job with 15,000+ steps daily on top of gym training and sport. Had to aggressive cut after a few months of holidays and just stupid food behaviours. Back on track now.
Goals are athletic recomp, lean down to 88-90kg, improve performance, then build lean mass on a Test E cycle.
Full Stack:
• Ostarine MK-2866 12.5mg daily sublingual (MrSarm 25mg/ml), started April 21
• Enclomiphene citrate 12.5mg every other day throughout cycle
• Retatrutide 2mg weekly up,
• KLOW 80mg blend 0.2ml daily subcut (BPC-157, TB-500, GHK-Cu, KPV) for joint recovery
• Tadalafil 5mg daily
• Creatine 5g daily, fish oil 4g, magnesium glycinate, ashwagandha, D3+K2 5000iu, zinc, milk thistle 550mg, glucosamine 1500mg, B12 methylcobalamin
Pre Cycle Baseline Bloods, April 16:
|Marker |Result |Range |
|-----------------|-----------|--------|
|Testosterone |15.3 nmol/L|9.2-31.8|
|SHBG |31 nmol/L |14-95 |
|Bioavailable T |7.8 nmol/L |2.5-12 |
|LH |not tested | |
|Oestradiol |not tested | |
|ALT |22 U/L |<40 |
|AST |24 U/L |<35 |
|eGFR |81 |>59 |
|Total Cholesterol|5.7 mmol/L |<5.6 |
|LDL |3.8 mmol/L |<3.1 |
|Triglycerides |0.6 mmol/L |<2.1 |
|Vitamin D |58 nmol/L |50-200 |
|Fasting Glucose |4.4 mmol/L |3.0-5.4 |
Mid Cycle Bloods, May 19 (Day 28 of cycle):
|Marker |Result |Range |vs Baseline |
|-----------------|-----------|---------|-------------|
|Testosterone |11.1 nmol/L|9.2-31.8 |down 4.2 |
|SHBG |10L nmol/L |14-95 |down 21 |
|Bioavailable T |8.5 nmol/L |2.5-12 |up 0.7 |
|LH |8.3 U/L |1.5-9.0 |normal |
|FSH |9.0H U/L |1.4-8.4 |slightly high|
|Oestradiol |170H pmol/L|<146 |elevated |
|Prolactin |171 mIU/L |45-375 |normal |
|FAI |111.0H % |14.5-80.3|high |
|ALT |33 U/L |<40 |up 11 |
|AST |23 U/L |<35 |stable |
|eGFR |88 |>59 |up 7 |
|Total Cholesterol|3.9 mmol/L |<5.6 |down 1.8 |
|LDL |2.7 mmol/L |<3.1 |down 1.1 |
|HDL |0.8L mmol/L|>0.9 |low |
|Triglycerides |0.9 mmol/L |<2.1 |stable |
|Fasting Glucose |4.7 mmol/L |3.0-5.4 |stable |
|HbA1c |4.7% |4.0-5.9 |normal |
|Vitamin D |75 nmol/L |50-200 |up 17 |
|PSA |0.35 ug/L |0.25-2.00|excellent |
Sorry that formatting is rough I’m on mobile.
Observations:
Suppression: Total testosterone dropped about 27% from 15.3 to 11.1 at week 4-5. What’s interesting is bioavailable testosterone actually went up slightly from 7.8 to 8.5 because SHBG crashed from 31 to 10. Subjectively I feel pretty good, minimal suppression symptoms. There’s a slight reduction in libido and some brain fog but I’m in an aggressive caloric deficit so I think that’s the main driver rather than hormonal suppression.
Estrogen: Oestradiol came back elevated at 170 against a range of less than 146. No gyno symptoms at all, no nipple sensitivity, no puffiness, nothing. My thinking is the elevated estrogen is partly driven by enclomiphene stimulating more testosterone production which gives more substrate for aromatisation, combined with the low SHBG environment. Not currently using an AI and not planning to until Test E. Keen to hear the community’s take on this.
LH: Sitting at 8.3 which is normal range. This tells me enclomiphene is doing its job keeping the HPG axis firing during cycle. Gives me confidence PCT recovery should be fairly smooth.
Lifting: Push pull legs throughout, training has been genuinely great. Strength has held up really well during the cut, recovery between sessions has been noticeably better, and overall I feel strong in the gym. Compounds have all moved up from where I started. Happy with how the training has responded to the cycle.
Lipids: Probably the most impressive part of the bloods. Total cholesterol down from 5.7 to 3.9, LDL from 3.8 to 2.7. I’m putting this down to Retatrutide’s metabolic effects combined with the weight loss and quitting nicotine earlier this year. HDL is sitting low at 0.8 against a range of greater than 0.9, working on this with 4g fish oil daily and zone 2 cardio.
Liver: ALT up from 22 to 33, still within range but trending up. Running milk thistle throughout and will add TUDCA for any future oral compounds.
Overall: Really positive experience with Ostarine at 12.5mg as a first compound. It’s subtle but effective, particularly for muscle preservation in a hard deficit. Joints have responded well to the KLOW blend.
PCT Plan:
• June 16, last Ostarine dose
• June 16, switch enclomiphene to 12.5mg daily
• Run 4 weeks
• Bloods around July 7 to confirm testosterone recovery back to 15.3 baseline
• Green light Test E if testosterone recovered and estrogen normalised
Planned Test E Cycle:
• Test E 300-400mg/week, Monday and Thursday pins
• Aromasin 12.5mg EOD on cycle
• Nolvadex on hand for emergency
• TUDCA for any future oral additions
• 12 week cycle
• Start date approximately mid July pending PCT bloods
Questions for the community:
1. Oestradiol at 170 with zero symptoms, AI now or let it self correct post cycle?
2. Enclomiphene 12.5mg EOD during cycle and 12.5mg daily for PCT, is that sufficient given this suppression level?
3. Any red flags in these bloods before proceeding to Test E?
4. HDL at 0.8, beyond fish oil and zone 2 cardio any specific interventions worth adding?
5. FAI elevated at 111, primarily a consequence of low SHBG, anything specific to address here?
6. Any general feedback on the stack or sequencing welcome
Thanks in advance EVO fam, I’m excited to hear everyone’s thoughts and feedback. Let me know if you need more information on anything
Background:
27 years old, 184cm, started at 107.5kg now at 98.8kg, down 8.7kg in 9 weeks. Active job with 15,000+ steps daily on top of gym training and sport. Had to aggressive cut after a few months of holidays and just stupid food behaviours. Back on track now.
Goals are athletic recomp, lean down to 88-90kg, improve performance, then build lean mass on a Test E cycle.
Full Stack:
• Ostarine MK-2866 12.5mg daily sublingual (MrSarm 25mg/ml), started April 21
• Enclomiphene citrate 12.5mg every other day throughout cycle
• Retatrutide 2mg weekly up,
• KLOW 80mg blend 0.2ml daily subcut (BPC-157, TB-500, GHK-Cu, KPV) for joint recovery
• Tadalafil 5mg daily
• Creatine 5g daily, fish oil 4g, magnesium glycinate, ashwagandha, D3+K2 5000iu, zinc, milk thistle 550mg, glucosamine 1500mg, B12 methylcobalamin
Pre Cycle Baseline Bloods, April 16:
|Marker |Result |Range |
|-----------------|-----------|--------|
|Testosterone |15.3 nmol/L|9.2-31.8|
|SHBG |31 nmol/L |14-95 |
|Bioavailable T |7.8 nmol/L |2.5-12 |
|LH |not tested | |
|Oestradiol |not tested | |
|ALT |22 U/L |<40 |
|AST |24 U/L |<35 |
|eGFR |81 |>59 |
|Total Cholesterol|5.7 mmol/L |<5.6 |
|LDL |3.8 mmol/L |<3.1 |
|Triglycerides |0.6 mmol/L |<2.1 |
|Vitamin D |58 nmol/L |50-200 |
|Fasting Glucose |4.4 mmol/L |3.0-5.4 |
Mid Cycle Bloods, May 19 (Day 28 of cycle):
|Marker |Result |Range |vs Baseline |
|-----------------|-----------|---------|-------------|
|Testosterone |11.1 nmol/L|9.2-31.8 |down 4.2 |
|SHBG |10L nmol/L |14-95 |down 21 |
|Bioavailable T |8.5 nmol/L |2.5-12 |up 0.7 |
|LH |8.3 U/L |1.5-9.0 |normal |
|FSH |9.0H U/L |1.4-8.4 |slightly high|
|Oestradiol |170H pmol/L|<146 |elevated |
|Prolactin |171 mIU/L |45-375 |normal |
|FAI |111.0H % |14.5-80.3|high |
|ALT |33 U/L |<40 |up 11 |
|AST |23 U/L |<35 |stable |
|eGFR |88 |>59 |up 7 |
|Total Cholesterol|3.9 mmol/L |<5.6 |down 1.8 |
|LDL |2.7 mmol/L |<3.1 |down 1.1 |
|HDL |0.8L mmol/L|>0.9 |low |
|Triglycerides |0.9 mmol/L |<2.1 |stable |
|Fasting Glucose |4.7 mmol/L |3.0-5.4 |stable |
|HbA1c |4.7% |4.0-5.9 |normal |
|Vitamin D |75 nmol/L |50-200 |up 17 |
|PSA |0.35 ug/L |0.25-2.00|excellent |
Sorry that formatting is rough I’m on mobile.
Observations:
Suppression: Total testosterone dropped about 27% from 15.3 to 11.1 at week 4-5. What’s interesting is bioavailable testosterone actually went up slightly from 7.8 to 8.5 because SHBG crashed from 31 to 10. Subjectively I feel pretty good, minimal suppression symptoms. There’s a slight reduction in libido and some brain fog but I’m in an aggressive caloric deficit so I think that’s the main driver rather than hormonal suppression.
Estrogen: Oestradiol came back elevated at 170 against a range of less than 146. No gyno symptoms at all, no nipple sensitivity, no puffiness, nothing. My thinking is the elevated estrogen is partly driven by enclomiphene stimulating more testosterone production which gives more substrate for aromatisation, combined with the low SHBG environment. Not currently using an AI and not planning to until Test E. Keen to hear the community’s take on this.
LH: Sitting at 8.3 which is normal range. This tells me enclomiphene is doing its job keeping the HPG axis firing during cycle. Gives me confidence PCT recovery should be fairly smooth.
Lifting: Push pull legs throughout, training has been genuinely great. Strength has held up really well during the cut, recovery between sessions has been noticeably better, and overall I feel strong in the gym. Compounds have all moved up from where I started. Happy with how the training has responded to the cycle.
Lipids: Probably the most impressive part of the bloods. Total cholesterol down from 5.7 to 3.9, LDL from 3.8 to 2.7. I’m putting this down to Retatrutide’s metabolic effects combined with the weight loss and quitting nicotine earlier this year. HDL is sitting low at 0.8 against a range of greater than 0.9, working on this with 4g fish oil daily and zone 2 cardio.
Liver: ALT up from 22 to 33, still within range but trending up. Running milk thistle throughout and will add TUDCA for any future oral compounds.
Overall: Really positive experience with Ostarine at 12.5mg as a first compound. It’s subtle but effective, particularly for muscle preservation in a hard deficit. Joints have responded well to the KLOW blend.
PCT Plan:
• June 16, last Ostarine dose
• June 16, switch enclomiphene to 12.5mg daily
• Run 4 weeks
• Bloods around July 7 to confirm testosterone recovery back to 15.3 baseline
• Green light Test E if testosterone recovered and estrogen normalised
Planned Test E Cycle:
• Test E 300-400mg/week, Monday and Thursday pins
• Aromasin 12.5mg EOD on cycle
• Nolvadex on hand for emergency
• TUDCA for any future oral additions
• 12 week cycle
• Start date approximately mid July pending PCT bloods
Questions for the community:
1. Oestradiol at 170 with zero symptoms, AI now or let it self correct post cycle?
2. Enclomiphene 12.5mg EOD during cycle and 12.5mg daily for PCT, is that sufficient given this suppression level?
3. Any red flags in these bloods before proceeding to Test E?
4. HDL at 0.8, beyond fish oil and zone 2 cardio any specific interventions worth adding?
5. FAI elevated at 111, primarily a consequence of low SHBG, anything specific to address here?
6. Any general feedback on the stack or sequencing welcome
Thanks in advance EVO fam, I’m excited to hear everyone’s thoughts and feedback. Let me know if you need more information on anything
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