You need some estrogen to up regulate the androgen receptors..
That’s all I know when it comes to building muscle.
I do know it helps a little with strength n loobricarion of the joints.
I personally don't really run into estrogen issues, and only need a little adex when running things like dianabol. How high levels of estrogen affect protein synthesis is an interesting question though, but unfortunately something I don't know the answer to. There's a lot of good info in this thread though, and I'll definitely be following along.
Can anyone give a definitive answer as to what effect if any estrogen, and especially elevated levels of estrogen, has on the process of protein synthesis? You obviously don't "blow up" as much using adex ob cycle, but what effect does it have on a cellular level?