Post Blast Labs and Spike in E2

[Buffbanker]

Currently on TRT and have been for the last year. I went on a 12 week blast of my normal TRT dose of Test C at 160 mg a week with 500 mg of Primo and 40 mg of Tbol for weeks 1-2 and 50 mg of Var for weeks 6-12. I also ran GW at 20 mg for the full 12 weeks. All PharmaCom gear. I use to be able to handle wet cycles much better back in the day but now I prefer DHT based cycles and not having to mess around with my E2 too much as I am fairly prone to sides when my T:E2 get out of whack. So I stuck with my normal .75 mg twice a week of Anastrozole during the start of my cycle. Well at my mid-cycle bloods I suspected low E2 or more so that the ratio of androgens in my body were much higher than E2 and sure enough although my E2 was at 24 pg/mL I was still having sides such as low penile sensitivity. So after reducing my Anastrozole dosage to 0.50 mg twice a week all was good again and felt great.

Well now comes times for my post-cycle labs and wanted to get dialed in before my next appointment with my TRT doc. So for the last maybe two months I have been back to my Anastrozole dose of 0.75 mg twice a week and low and behold my E2 comes back at 277! Wait a minute how is that possible with TT at 1167 ng/dL (LabCorp ranges) and FT at 41 pg/mL. How could I be a bit outside of range for TT and FT but 7 times out of range for E2!? So the lab agreed that it didn’t seem right either so a retest was ordered. They did call me and confirm they could not validate my last results so at least they admitted their issue. Well I got my retest results back and my E2 is still higher than it ever has been at 58. My Anastrozole is custom compounded and pharma grade so it can’t be that. Same for my Test C which I haven’t changed the dose on either at 160 mg a week. I believe the PharmaCom gear to be legit as my mid cycle bloods showed no increased aromatization and my TT actually came down slightly which is what I typically see when running DHT compounds that reduce your SBHG and therefore cause a slight reduction in TT. So either something is causing a random spike in estrogen in the face of my normal TRT and Anastrozole protocol, the lab results are questionable again, or ....?

The only other items worth mentioned are that I dropped HCG a week before my retest as I always felt like I bloated from it anyway even when I crashed my E2 trying to get my TRT protocol dialed in. And the fact that I am taking a tetracycline for acne which LabCorp confirmed does not affect the E2 sensitive assay. Anyone experience any estrogen spikes like this after a DHT cycle while cruising?

 

[Mobster]

Currently on TRT and have been for the last year. I went on a 12 week blast of my normal TRT dose of Test C at 160 mg a week with 500 mg of Primo and 40 mg of Tbol for weeks 1-2 and 50 mg of Var for weeks 6-12. I also ran GW at 20 mg for the full 12 weeks. All PharmaCom gear. I use to be able to handle wet cycles much better back in the day but now I prefer DHT based cycles and not having to mess around with my E2 too much as I am fairly prone to sides when my T:E2 get out of whack. So I stuck with my normal .75 mg twice a week of Anastrozole during the start of my cycle. Well at my mid-cycle bloods I suspected low E2 or more so that the ratio of androgens in my body were much higher than E2 and sure enough although my E2 was at 24 pg/mL I was still having sides such as low penile sensitivity. So after reducing my Anastrozole dosage to 0.50 mg twice a week all was good again and felt great.

Well now comes times for my post-cycle labs and wanted to get dialed in before my next appointment with my TRT doc. So for the last maybe two months I have been back to my Anastrozole dose of 0.75 mg twice a week and low and behold my E2 comes back at 277! Wait a minute how is that possible with TT at 1167 ng/dL (LabCorp ranges) and FT at 41 pg/mL. How could I be a bit outside of range for TT and FT but 7 times out of range for E2!? So the lab agreed that it didn’t seem right either so a retest was ordered. They did call me and confirm they could not validate my last results so at least they admitted their issue. Well I got my retest results back and my E2 is still higher than it ever has been at 58. My Anastrozole is custom compounded and pharma grade so it can’t be that. Same for my Test C which I haven’t changed the dose on either at 160 mg a week. I believe the PharmaCom gear to be legit as my mid cycle bloods showed no increased aromatization and my TT actually came down slightly which is what I typically see when running DHT compounds that reduce your SBHG and therefore cause a slight reduction in TT. So either something is causing a random spike in estrogen in the face of my normal TRT and Anastrozole protocol, the lab results are questionable again, or ....?

The only other items worth mentioned are that I dropped HCG a week before my retest as I always felt like I bloated from it anyway even when I crashed my E2 trying to get my TRT protocol dialed in. And the fact that I am taking a tetracycline for acne which LabCorp confirmed does not affect the E2 sensitive assay. Anyone experience any estrogen spikes like this after a DHT cycle while cruising?

What do you mean by 'currently'? TRT is for life.

 

[stevesmi]

I will tell you EXACTLY what happened

your primo is really tren

tren is many tests will give a false reading for estrogen. tren is way more cheaper than primo, so your source probably laced your primo with tren and something else and/or their raw supplier sold them laced primo.

 

[Fella Finn]

What do you mean by 'currently'? TRT is for life.

I think he meant to say a lil 'cruise'?

 

[Nismo99]

I wouldn’t freak out over an e2 of 58 as long as you feel well, and no signs of gyno or other sides. People really need to stop chasing labs numbers. I bet if you get tested again the e2 will be a different number. Lots of variables can affect hormone levels.

 

[Mobster]

I think he meant to say a lil 'cruise'?

50% of the time when they say TRT they mean 'TRT like dose'. So yeah a cruise.

 

[Buffbanker]

50% of the time when they say TRT they mean 'TRT like dose'. So yeah a cruise.

No I mean TRT and obviously it’s for life. As in I am paying for mistakes I made from my younger days with improper PCT mostly from the lack of knowledge at my disposal of proper use of HCG 15 years ago. Also this should be a lesson for any 25 year old blasting cycles without proper research, guidance, and PCT. Been there, done that, now I have a member for life card in my wallet.

 

[Buffbanker]

I will tell you EXACTLY what happened

your primo is really tren

tren is many tests will give a false reading for estrogen. tren is way more cheaper than primo, so your source probably laced your primo with tren and something else and/or their raw supplier sold them laced primo.

My mid cycle labs were around weeks 4-5 which if that were the case it should have skewed my E2 at that time when it came back at 24 pg/mL. It’s possible it was laced but I would expect skewed E2 at 4-5 weeks versus 8 weeks post cycle. The var was the only compound I was not running at the time I had my mid cycle labs. And I thought Tren only skews ECLIA assays and not the sensitive LC/MS.

 

[Mobster]

No I mean TRT and obviously it’s for life. As in I am paying for mistakes I made from my younger days with improper PCT mostly from the lack of knowledge at my disposal of proper use of HCG 15 years ago. Also this should be a lesson for any 25 year old blasting cycles without proper research, guidance, and PCT. Been there, done that, now I have a member for life card in my wallet.

Stick around fella - we need more like you to pass on this info to others

 

[Buffbanker]

I wouldn’t freak out over an e2 of 58 as long as you feel well, and no signs of gyno or other sides. People really need to stop chasing labs numbers. I bet if you get tested again the e2 will be a different number. Lots of variables can affect hormone levels.

More than likely. Yet, getting dialed in on TRT is much more finite when dealing with smaller ranges that allow for improvement of symptoms or optimization of your hormone levels. I am good down to an E2 of 15 and up to 40 but outside of those I start to suffer sides. And at 58 (if accurate) my acne has returned which for me is a high and low side unfortunately. I also believe there is more to the ratio of T:E2 as well as DHT:E2 than any exact number or range. I go by feel and labs as without the latter you’re making stabs in the dark. Plus for the time being until we have long term studies on healthy males on TRT there is a lot to be learned from E2 management.

 

[Buffbanker]

Stick around fella - we need more like you to pass on this info to others

Appreciate that and I wish my coaches back in college would have done the same for me. Unfortunately I believe it is worse now than it ever has been....

 

[muskate]

My mid cycle labs were around weeks 4-5 which if that were the case it should have skewed my E2 at that time when it came back at 24 pg/mL. It’s possible it was laced but I would expect skewed E2 at 4-5 weeks versus 8 weeks post cycle. The var was the only compound I was not running at the time I had my mid cycle labs. And I thought Tren only skews ECLIA assays and not the sensitive LC/MS.

Your var wasn't var then. It was probably a very estrogenic steroid like dbol or anadrol

 

[Masonic Bodybuilder]

Appreciate that and I wish my coaches back in college would have done the same for me. Unfortunately I believe it is worse now than it ever has been....

I hear this story way too often. Fucking disgusting what goes on in sports with regards to AAS.

 

[Buffbanker]

Your var wasn't var then. It was probably a very estrogenic steroid like dbol or anadrol

Wouldn’t at 8 weeks post cycle, even if it was dbol or anadrol, that it wouldn’t have any impact on estrogen by that point? If it was a long ester then I could see but we are talking orals with 5-10 hour half life’s. I am wondering if there is another pathway to estrogen rebound or increased aromatase activity when elevated DHT and low SHBG reverses?

I upped my anastrozole dose to 1 mg twice a week which still seems a bit much given 160mg a week of Test C. I will retest bloods again in 4 weeks.

 

[muskate]

Wouldn’t at 8 weeks post cycle, even if it was dbol or anadrol, that it wouldn’t have any impact on estrogen by that point? If it was a long ester then I could see but we are talking orals with 5-10 hour half life’s. I am wondering if there is another pathway to estrogen rebound or increased aromatase activity when elevated DHT and low SHBG reverses?

I upped my anastrozole dose to 1 mg twice a week which still seems a bit much given 160mg a week of Test C. I will retest bloods again in 4 weeks.

At the end of the day - no one knows what drug you took. It's impossible to know. We are all just guessing.

 

[awm1981]

So unlike Aromasin which is a suicide AI, arimidex can be know to have rebound so when you stopped taking it maybe your E2 spiked?

Other than that not really sure? I would switch to aromasin (if you can) and see if that helps.

 

[Fella Finn]

No I mean TRT and obviously it’s for life. As in I am paying for mistakes I made from my younger days with improper PCT mostly from the lack of knowledge at my disposal of proper use of HCG 15 years ago. Also this should be a lesson for any 25 year old blasting cycles without proper research, guidance, and PCT. Been there, done that, now I have a member for life card in my wallet.

A message worth double quoting.

 

[Mobster]

A message worth double quoting.

Read this and weep kids.

 

[ReiminkGYM]

Thanks for nice news

 

[stevesmi]

run bloods ..

 

[muskate]

So unlike Aromasin which is a suicide AI, arimidex can be know to have rebound so when you stopped taking it maybe your E2 spiked?

Other than that not really sure? I would switch to aromasin (if you can) and see if that helps.

Agreed.

Or maybe his arimidex was actually letro?

I have no idea what he actually took but something shady is going on with his source