Sterile inflammatory response?

[plateitup]

Hey guys!

I’ve been dealing with a pretty bad inflammatory reaction after injections and I’m trying to figure out what’s causing it.
Whenever I inject, I don’t just get normal post-injection pain — I get flu-like symptoms too. Chills, feverish feeling, body aches, fatigue, and the injection site gets red, swollen, warm to the touch, and forms a lump/oil depot. It usually takes 7–10 days to settle, which basically ruins my week for work, gym, and general life.

I’m using 250 mg/mL Test E and 250 mg/mL Primo E, and both cause the same issue, although Primo is definitely worse and lasts longer. I’ve tried products from three different trusted sources, and they all use MCT oil, BA, and BB. Other people seem fine with the same vendors, so it seems like I’m personally reacting badly to something.

The only time I didn’t get the same reaction was with pharma Bayer Test E 250 mg/mL, which used castor oil and BB. I still had some PIP, but no flu-like symptoms.

I’ve tried smaller and more frequent injections, mixing compounds, diluting with extra MCT oil, and keeping volumes low. VG is the only site I can somewhat tolerate; delts are basically impossible, especially with higher volume.

At this point, it doesn’t feel like normal PIP. Could this be a reaction to MCT oil, BA, BB, the concentration, or something else? Has anyone dealt with this or found a solution?

 

[Mobster]

Hey guys!

I’ve been dealing with a pretty bad inflammatory reaction after injections and I’m trying to figure out what’s causing it.
Whenever I inject, I don’t just get normal post-injection pain — I get flu-like symptoms too. Chills, feverish feeling, body aches, fatigue, and the injection site gets red, swollen, warm to the touch, and forms a lump/oil depot. It usually takes 7–10 days to settle, which basically ruins my week for work, gym, and general life.

I’m using 250 mg/mL Test E and 250 mg/mL Primo E, and both cause the same issue, although Primo is definitely worse and lasts longer. I’ve tried products from three different trusted sources, and they all use MCT oil, BA, and BB. Other people seem fine with the same vendors, so it seems like I’m personally reacting badly to something.

The only time I didn’t get the same reaction was with pharma Bayer Test E 250 mg/mL, which used castor oil and BB. I still had some PIP, but no flu-like symptoms.

I’ve tried smaller and more frequent injections, mixing compounds, diluting with extra MCT oil, and keeping volumes low. VG is the only site I can somewhat tolerate; delts are basically impossible, especially with higher volume.

At this point, it doesn’t feel like normal PIP. Could this be a reaction to MCT oil, BA, BB, the concentration, or something else? Has anyone dealt with this or found a solution?

Yes. We know some members cannot handle some oils

 

[Kingofspades712]

That sucks man. I know for me personally I was getting extremely bad PIP from para Pharma Sust 350. My brother had the exact same vial. We ordered our cycles in the same order. He had 0 pip from his. I had to switch to Test CYP 250 from Para Pharma. I couldn’t handle the PIP anymore. Your best bet is to try switching to Cyp. You can’t really compare your test to Primo 250 as, primo 250 is generally going to kick like a mule. That’s the downside of anything over 100mg/ml primo.
Try cyp and see if it’s just the oil from the Test E. If you get the same PIP from Cyp you might be fucked

 

[Kingofspades712]

Another thing to do is try splitting your pins to daily injections. Smaller oil deposits each time might help. I prefer a 25 gauge 5/8” needle for my daily pins.

 

[stevesmi]

Your body thinks it’s under attack so it freaks out and you get an immune response. Same issues happen with orals?

 

[toddthelineman]

That’s high concentration primo. If I put that in my ass I would possibly be unable to walk. 200mg/ml primo had me at the hospital because I didn’t know it could get that bad and I figured I must have an infection. I would never buy anything but 100mg/ml primo

 

[plateitup]

Your body thinks it’s under attack so it freaks out and you get an immune response. Same issues happen with orals?

No, no issue whatsoever with orals. I took Anavar 25mg for a couple if weeks with no issues.

 

[plateitup]

Another thing to do is try splitting your pins to daily injections. Smaller oil deposits each time might help. I prefer a 25 gauge 5/8” needle for my daily pins.

Hey man thanks for the response. I tried splitting the dose up into daily injections using a 25g 1inch but I was having the same issues. I am going to switch to Cyo and see how I go

 

[plateitup]

That’s high concentration primo. If I put that in my ass I would possibly be unable to walk. 200mg/ml primo had me at the hospital because I didn’t know it could get that bad and I figured I must have an infection. I would never buy anything but 100mg/ml primo

Definitely. The primo concentration is insanely high. I've tried primo 100mg/mL and 200mg/mL. Both caused the same issue. The flu like symptoms, swelling, and unable to walk when injected in the VG. I got this 250 from my friend who advised me to try it and see if it causes me any issues, and it's hit me like a bus.

 

[plateitup]

Yes. We know some members cannot handle some oils

So what would you advise them to do? What can I get that I can tolerate and not get a crippling immune response from

 

[stevesmi]

No, no issue whatsoever with orals. I took Anavar 25mg for a couple if weeks with no issues.

that would be the route i would go then. i know people who have used orals for 30 years and never used injectables, it can be done

 

[toddthelineman]

Definitely. The primo concentration is insanely high. I've tried primo 100mg/mL and 200mg/mL. Both caused the same issue. The flu like symptoms, swelling, and unable to walk when injected in the VG. I got this 250 from my friend who advised me to try it and see if it causes me any issues, and it's hit me like a bus.

I never got the flu stuff. Just incredible swelling and pain in the area of injection. Your friend is a real joker lmao

 

[Kingofspades712]

I must ask. Are you getting gear from around town where you live or from a respected site like advertised on here? Let’s start there

 

[LevButlerov]

Hey guys!

I’ve been dealing with a pretty bad inflammatory reaction after injections and I’m trying to figure out what’s causing it.
Whenever I inject, I don’t just get normal post-injection pain — I get flu-like symptoms too. Chills, feverish feeling, body aches, fatigue, and the injection site gets red, swollen, warm to the touch, and forms a lump/oil depot. It usually takes 7–10 days to settle, which basically ruins my week for work, gym, and general life.

I’m using 250 mg/mL Test E and 250 mg/mL Primo E, and both cause the same issue, although Primo is definitely worse and lasts longer. I’ve tried products from three different trusted sources, and they all use MCT oil, BA, and BB. Other people seem fine with the same vendors, so it seems like I’m personally reacting badly to something.

The only time I didn’t get the same reaction was with pharma Bayer Test E 250 mg/mL, which used castor oil and BB. I still had some PIP, but no flu-like symptoms.

I’ve tried smaller and more frequent injections, mixing compounds, diluting with extra MCT oil, and keeping volumes low. VG is the only site I can somewhat tolerate; delts are basically impossible, especially with higher volume.

At this point, it doesn’t feel like normal PIP. Could this be a reaction to MCT oil, BA, BB, the concentration, or something else? Has anyone dealt with this or found a solution?

This is not normal PIP and could be a reaction to MCT or the solvent mix BA BB, but infection must be ruled out as well. did you actually measure your fever level? are we talking over 100F?

 

[plateitup]

that would be the route i would go then. i know people who have used orals for 30 years and never used injectables, it can be done

But I'd still love to take injectable testosterone, primo, mast, etc. Injectables are just safer on the liver.

 

[plateitup]

I never got the flu stuff. Just incredible swelling and pain in the area of injection. Your friend is a real joker lmao

Hahaha well we kept on assuming might be the source of the Primo. Yeah I think the flu stuff is that the local inflammatory response is becoming systemic (more severe) and just destroys me haha

 

[plateitup]

This is not normal PIP and could be a reaction to MCT or the solvent mix BA BB, but infection must be ruled out as well. did you actually measure your fever level? are we talking over 100F?

Definitely not normal at all. I've ruled out infection because I have been injecting for the last 3 months or so and I get the same response everytime regardless of the source. So I'm certain it's not a sterility issue but a reaction to the solvent mix or carrier oil. I haven't measured my fever, however it is systemic symptoms like muscle aches, tiredness.

 

[plateitup]

I must ask. Are you getting gear from around town where you live or from a respected site like advertised on here? Let’s start there

All sources were sourced from verified and trusted vendors.

 

[LevButlerov]

Definitely not normal at all. I've ruled out infection because I have been injecting for the last 3 months or so and I get the same response everytime regardless of the source. So I'm certain it's not a sterility issue but a reaction to the solvent mix or carrier oil. I haven't measured my fever, however it is systemic symptoms like muscle aches, tiredness.

its possible you have an allergic reaction, how many times in the past have you used gear?

 

[Kingofspades712]

What you’re describing is not normal PIP sounds more severe borderline infection. Oils must put your immune system into fight mode. You got dealt a bad hand my friend. Idk what I’d do. Probably would stop putting my body through it though. Pain is one thing but yours sounds beyond that. If Cyp doesn’t work you might need to hang it up. Go natty

 

[plateitup]

What you’re describing is not normal PIP sounds more severe borderline infection. Oils must put your immune system into fight mode. You got dealt a bad hand my friend. Idk what I’d do. Probably would stop putting my body through it though. Pain is one thing but yours sounds beyond that. If Cyp doesn’t work you might need to hang it up. Go natty

Natty? Hahaha that's a nightmare. But yes it definitely feels like a borderline infection. What I'm trying to figure out though is what ingredient in the oil is sending my immune system crazy, then hopefully I can go the legitimate route and get some compounded test or something.

 

[plateitup]

its possible you have an allergic reaction, how many times in the past have you used gear?

Definitely not an allergic reaction because I'm not having symptoms of an allergic reaction such as a rash or itchiness. It's more of an inflammatory response.

 

[LevButlerov]

Definitely not an allergic reaction because I'm not having symptoms of an allergic reaction such as a rash or itchiness. It's more of an inflammatory response.

I would be careful saying "definitely" on anything in our industry, please post actual pics of the site close and wide angle thanks @plateitup

 

[Grim Sleeper]

I have run into a similar issue, though nowhere near as severe as yours. I get zero pip from my pharma test which is in a cotton seed oil carrier. Recently tried to switch to Test with MCT carrier through a trusted vendor here and have had pretty severe PIP with every injection. Interestingly, I also bought some EQ @ 400mg/ml in MCT from the same vendor which I’ve been able to continue using by mixing with my pharma test at low volumes. Not sure what you have access to wherever you are, but if any of your vendors do a Test in Grape Seed or Cotton Seed oil I’d try those and see if they agree with you.

 

[LevButlerov]

I have run into a similar issue, though nowhere near as severe as yours. I get zero pip from my pharma test which is in a cotton seed oil carrier. Recently tried to switch to Test with MCT carrier through a trusted vendor here and have had pretty severe PIP with every injection. Interestingly, I also bought some EQ @ 400mg/ml in MCT from the same vendor which I’ve been able to continue using by mixing with my pharma test at low volumes. Not sure what you have access to wherever you are, but if any of your vendors do a Test in Grape Seed or Cotton Seed oil I’d try those and see if they agree with you.

You should try baking it with pin on top might actually help

 

[Grim Sleeper]

You should try baking it with pin on top might actually help

Baking it

 

[Oowua]

I’ve had something similar a few years ago, and I’ve had it since but rarely.

I think it could be a combination of 2 things here.

1- large amount of oil into the muscle (side delt is where I had the problem)

2- bad injection! Injecting between the overlapping muscles or going too deep with pin or even hitting a nerve. (Which I got when doing quads)

 

[Oowua]

Try a more shallow injection

Past subcutaneous but not deep deep into the muscle

Maybe 3/4 inch deep

 

[Mobster]

So what would you advise them to do? What can I get that I can tolerate and not get a crippling immune response from

Find out what oil is in the products causing the issue and ask sources (see our banner ads) what oils are in their product. Use products with different oils - simples

 

[HarleyGuy]

All sources were sourced from verified and trusted vendors.

Don't leave us hanging bro which source.

I've seen issues with some over MCT oil. Fever no good though that's an issue

I would never buy anything but 100mg/ml primo

LOL I guess I'm lucky.... I've done anything from 200mg Primo to 500mg Sust and no issues at all. I've seen it put guys down for 2 days though depends for sure. PIP for me is just a nice little sidekick reminding me it's working but yours sounded deadly!

 

[plateitup]

I have run into a similar issue, though nowhere near as severe as yours. I get zero pip from my pharma test which is in a cotton seed oil carrier. Recently tried to switch to Test with MCT carrier through a trusted vendor here and have had pretty severe PIP with every injection. Interestingly, I also bought some EQ @ 400mg/ml in MCT from the same vendor which I’ve been able to continue using by mixing with my pharma test at low volumes. Not sure what you have access to wherever you are, but if any of your vendors do a Test in Grape Seed or Cotton Seed oil I’d try those and see if they agree with you.

Yeah I've gone ahead and just ordered some 250mg/mL of test E in GSO, hopefully that'll fix the issue.

 

[plateitup]

Find out what oil is in the products causing the issue and ask sources (see our banner ads) what oils are in their product. Use products with different oils - simples

All of them are MCT. I just ordered some test E in GSO from Raptor so hopefully that fixes everything.

 

[plateitup]

Don't leave us hanging bro which source.

I've seen issues with some over MCT oil. Fever no good though that's an issue


LOL I guess I'm lucky.... I've done anything from 200mg Primo to 500mg Sust and no issues at all. I've seen it put guys down for 2 days though depends for sure. PIP for me is just a nice little sidekick reminding me it's working but yours sounded deadly!

Ye fever and cold chills be deadly. I can't give them name of the vendors cause they are verified on other forums. However, one of them is RaptorLabs. Nothing wrong with the lab or the batch because my mate injected it and was g2g no pip.

 

[plateitup]

I’ve had something similar a few years ago, and I’ve had it since but rarely.

I think it could be a combination of 2 things here.

1- large amount of oil into the muscle (side delt is where I had the problem)

2- bad injection! Injecting between the overlapping muscles or going too deep with pin or even hitting a nerve. (Which I got when doing quads)

I should mention. I did try injecting daily but it didn't help. I was still getting same symptoms. I've tried different needle lengths and gauges but it hasn't really helped.

 

[stevesmi]

But I'd still love to take injectable testosterone, primo, mast, etc. Injectables are just safer on the liver.

Try different brands

 

[Mobster]

All of them are MCT. I just ordered some test E in GSO from Raptor so hopefully that fixes everything.

Awesome. GSO seems to be the least allergic response prone

 

[Mobster]

Ye fever and cold chills be deadly. I can't give them name of the vendors cause they are verified on other forums. However, one of them is RaptorLabs. Nothing wrong with the lab or the batch because my mate injected it and was g2g no pip.

Deffo an allergic response by you then. Avoid MCT oils

 

[plateitup]

Thanks for all the advice guys. I love y'all. Going to get this GSO test, sus it and report back.

 

[2Thick]

Hey guys!

I’ve been dealing with a pretty bad inflammatory reaction after injections and I’m trying to figure out what’s causing it.
Whenever I inject, I don’t just get normal post-injection pain — I get flu-like symptoms too. Chills, feverish feeling, body aches, fatigue, and the injection site gets red, swollen, warm to the touch, and forms a lump/oil depot. It usually takes 7–10 days to settle, which basically ruins my week for work, gym, and general life.

I’m using 250 mg/mL Test E and 250 mg/mL Primo E, and both cause the same issue, although Primo is definitely worse and lasts longer. I’ve tried products from three different trusted sources, and they all use MCT oil, BA, and BB. Other people seem fine with the same vendors, so it seems like I’m personally reacting badly to something.

The only time I didn’t get the same reaction was with pharma Bayer Test E 250 mg/mL, which used castor oil and BB. I still had some PIP, but no flu-like symptoms.

I’ve tried smaller and more frequent injections, mixing compounds, diluting with extra MCT oil, and keeping volumes low. VG is the only site I can somewhat tolerate; delts are basically impossible, especially with higher volume.

At this point, it doesn’t feel like normal PIP. Could this be a reaction to MCT oil, BA, BB, the concentration, or something else? Has anyone dealt with this or found a solution?

you need to keep experimenting. you are sensitive to some sort of oil

 

[Ulter]

Thanks for all the advice guys. I love y'all. Going to get this GSO test, sus it and report back.

That's good that you're not being stubborn. Too many people are stubborn and just accept the way things are.

 

[ROIDDERS]

Thanks for all the advice guys. I love y'all. Going to get this GSO test, sus it and report back.

talk to the source and explain the issue. talk to the specific reps on here for those sources and see if they can suggest something. maybe they can send you a few vials of gear to try out with different oils

 

[ceo]

Awesome. GSO seems to be the least allergic response prone

bros i think this could be it. but could be other things in the oils too that can aggravate

 

[Mobster]

bros i think this could be it. but could be other things in the oils too that can aggravate

Also true. If the BA is off by a fraction that can sting. As can, although rare now, high dose products (350-500mg a ml)

 

[ballin2504]

I’d definitely try a a different brand brother

 

[Oowua]

I should mention. I did try injecting daily but it didn't help. I was still getting same symptoms. I've tried different needle lengths and gauges but it hasn't really helped.

Bummer dude

 

[LevButlerov]

Baking it

you stick a pin in the top and put the vial half way into hot (not boiling) water, will let some BA out

 

[Oowua]

T

you stick a pin in the top and put the vial half way into hot (not boiling) water, will let some BA out

This is a interesting little trick

 

[LevButlerov]

T

This is a interesting little trick

it looks like this see image below @Oowua

 

[ceo]

Also true. If the BA is off by a fraction that can sting. As can, although rare now, high dose products (350-500mg a ml)

Bros, it's possible. Everybody is different.

 

[Kingofspades712]

it looks like this see image below @Oowua

What does that do? Looks interesting

 

[Oowua]

it looks like this see image below @Oowua

Very cool trick

 

[Grim Sleeper]

it looks like this see image below @Oowua

I did this last night with one of my vials, interested to see if it has any impact. Fucking cool trick if it works!

 

[LevButlerov]

I did this last night with one of my vials, interested to see if it has any impact. Fucking cool trick if it works!

heat up but dont boil like hot to the touch water

 

[LevButlerov]

What does that do? Looks interesting

clears out the extra ba in general but we use it to clear crystalization mainly in the winter

 

[Dasgearizgoodyalol]

Hey guys!

I’ve been dealing with a pretty bad inflammatory reaction after injections and I’m trying to figure out what’s causing it.
Whenever I inject, I don’t just get normal post-injection pain — I get flu-like symptoms too. Chills, feverish feeling, body aches, fatigue, and the injection site gets red, swollen, warm to the touch, and forms a lump/oil depot. It usually takes 7–10 days to settle, which basically ruins my week for work, gym, and general life.

I’m using 250 mg/mL Test E and 250 mg/mL Primo E, and both cause the same issue, although Primo is definitely worse and lasts longer. I’ve tried products from three different trusted sources, and they all use MCT oil, BA, and BB. Other people seem fine with the same vendors, so it seems like I’m personally reacting badly to something.

The only time I didn’t get the same reaction was with pharma Bayer Test E 250 mg/mL, which used castor oil and BB. I still had some PIP, but no flu-like symptoms.

I’ve tried smaller and more frequent injections, mixing compounds, diluting with extra MCT oil, and keeping volumes low. VG is the only site I can somewhat tolerate; delts are basically impossible, especially with higher volume.

At this point, it doesn’t feel like normal PIP. Could this be a reaction to MCT oil, BA, BB, the concentration, or something else? Has anyone dealt with this or found a solution?

I know EXACTLY what you are talking about. I’ve been pinning 250mg/ml sust in my glutes for a while with no issues. UNTIL, I thought I’d take it up a notch and switched to ULTIMA SUS 500mg/ml. It only took a few hours before I knew, Houston we have a problem lol. There was a hard lump at the site which I’d never had before. Then came the low grade fever and the rest of the pain train! Wow, I don’t think I’ve had flu symptoms that bad when i actually had the flu! The next morning I felt miserable but I’m a firefighter and thus drug my illin arce to work. I think it took 4 days to subside. I’ve gotten some more 250mg sust but waiting till I have a few days off to try it. Like I said I’d been good with the 250mg for a while, hell I’d never heard of test flu.
Best of luck to ya