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Bois (and ladies), science has spoken.
Was listening to the latest The Diary Of A CEO episode today and found it really interesting.
Two studies, 27 years apart, both saying the same thing. The blokes and women getting more action are dying less. Couldn't make this up if I tried.
Study 1: Caerphilly Cohort (Wales, BMJ 1997)
918 Welsh blokes aged 45 to 59, tracked for 10 years. The high orgasm frequency group had half the all-cause mortality of the low frequency group. Adjusted odds ratio 2.0 for low frequency (P=0.02 trend). Dose response too, more was better. Source: BMJ 315:1641-1644 (Smith, Frankel, Yarnell 1997).
Study 2: NHANES analysis (Scientific Reports 2024)
US data, 17,243 adults, 11 year follow up. Headlines:
Why this matters for us all
We have lots of conversations on this forum are libido this, libido that. Cruise libido, blast libido, post-cycle libido, fertility-protocol libido, AI-managed E2 libido. We obsess over E2, free T, prolactin, dopamine, the entire panel. Turns out the actual frequency might matter for the cardiovascular and mortality side too, independent of bloods.
Practical takes (only half joking):
The masturbation and porn elephant
Right, the question half of you are already typing. What about the solo missions?
Free protocol: AM sex (before anyone reaches for a script
)
The body has a built-in bonus round most blokes overlook. Morning wood (nocturnal penile tumescence) is the leftover from REM-cycle erections through the night, you wake up with the gear already most of the way online. Same wiring runs in women too, the equivalent is called (nocturnal clitoral tumescence), less obvious to spot but the engorgement and lubrication are pre-loaded the same way, typically occurs 4-5 times per night in women and is considered a sign of healthy blood flow and nerve function.
What this means in practice: AM sex is the cheat code. Both sets of plumbing are primed by the night's REM cycles. Less foreplay required to get there, less performance pressure on either side, and it's the one window where a crashed E2, dead-cruise libido, or general "head not in it" matters less because the hardware is already up before the brain has a chance to overthink it.
Bonus: AM sex sets the cortisol curve, mood, and the missus's whole day in the right direction at the same time. Free win all round.
Caveat: shift workers, the perpetually stressed, and the chronically under-slept don't get the AM wood signal cleanly. If you wake up flat 5+ days a week, that's a sleep architecture or hormonal flag, not a "she's lost interest" issue. Bloods + sleep audit before you assume anything else.
The PDE5 staples (the backbone for most of us)
Quick recap on the bread and butter for the bedroom department, since half the blokes here are already running at least one:
A few peptides from @Prymal's shelf actually pull real weight in this conversation:
Curious where the rest of you sit.
Was listening to the latest The Diary Of A CEO episode today and found it really interesting.
Two studies, 27 years apart, both saying the same thing. The blokes and women getting more action are dying less. Couldn't make this up if I tried.
Study 1: Caerphilly Cohort (Wales, BMJ 1997)
918 Welsh blokes aged 45 to 59, tracked for 10 years. The high orgasm frequency group had half the all-cause mortality of the low frequency group. Adjusted odds ratio 2.0 for low frequency (P=0.02 trend). Dose response too, more was better. Source: BMJ 315:1641-1644 (Smith, Frankel, Yarnell 1997).
Study 2: NHANES analysis (Scientific Reports 2024)
US data, 17,243 adults, 11 year follow up. Headlines:
- Women with low frequency: 70% higher mortality risk vs weekly+ (HR 1.70)
- Depressed adults at very-low frequency: 197% higher risk vs weekly. Wild number
- CVD patients: HR 2.3 with low frequency, drops back to ~1.0 with moderate-to-high frequency
Why this matters for us all
We have lots of conversations on this forum are libido this, libido that. Cruise libido, blast libido, post-cycle libido, fertility-protocol libido, AI-managed E2 libido. We obsess over E2, free T, prolactin, dopamine, the entire panel. Turns out the actual frequency might matter for the cardiovascular and mortality side too, independent of bloods.
Practical takes (only half joking):
- Crashing E2 to chase abs is now officially a longevity sin. Go figure
- Coming off properly so the fertility protocol restores libido isn't just for keeping the missus happy. There's a real cardiovascular dividend in the deal
- "TRT saved my marriage" stories aren't just feel good. The biomarker backing exists
- If your other half ever side-eyes the cycle, you can now cite peer reviewed evidence that this is essentially preventative medicine
The masturbation and porn elephant
Right, the question half of you are already typing. What about the solo missions?
- The Caerphilly study tracked orgasmic frequency, not specifically partnered sex. So on that one, solo technically counts
- The NHANES findings on cardiovascular and mortality were strongest in partnered contexts. The likely reason is partnered sex brings the heart rate load plus the oxytocin spike that solo-with-a-screen does not trigger the same way
- Porn brain is the other side. Dopamine receptor downregulation from endless novelty is real, and porn-induced ED in young men keeps showing up in the literature. The same wiring catches blokes in PCT or dead-cruise mode when the bedroom struggle is already on.
- Death grip syndrome is also a thing. If you only finish with an aggressive solo grip, real partnered sensation feels like a downgrade. Worth knowing if you've been wondering why the missus is suddenly underwhelming through no fault of her own.
Free protocol: AM sex (before anyone reaches for a script
)The body has a built-in bonus round most blokes overlook. Morning wood (nocturnal penile tumescence) is the leftover from REM-cycle erections through the night, you wake up with the gear already most of the way online. Same wiring runs in women too, the equivalent is called (nocturnal clitoral tumescence), less obvious to spot but the engorgement and lubrication are pre-loaded the same way, typically occurs 4-5 times per night in women and is considered a sign of healthy blood flow and nerve function.
What this means in practice: AM sex is the cheat code. Both sets of plumbing are primed by the night's REM cycles. Less foreplay required to get there, less performance pressure on either side, and it's the one window where a crashed E2, dead-cruise libido, or general "head not in it" matters less because the hardware is already up before the brain has a chance to overthink it.
Bonus: AM sex sets the cortisol curve, mood, and the missus's whole day in the right direction at the same time. Free win all round.
Caveat: shift workers, the perpetually stressed, and the chronically under-slept don't get the AM wood signal cleanly. If you wake up flat 5+ days a week, that's a sleep architecture or hormonal flag, not a "she's lost interest" issue. Bloods + sleep audit before you assume anything else.
The PDE5 staples (the backbone for most of us)
Quick recap on the bread and butter for the bedroom department, since half the blokes here are already running at least one:
- Cialis (Tadalafil) long half life around 17.5 hours, so most run it as a daily 5mg low dose. Bonus: lowers BP and helps the pump in the gym, off-label win when blast season has the arms feeling like Christmas hams.
- Viagra (Sildenafil) short half life around 4 hours, on-demand only. Faster onset than Cialis but eat a fatty meal first and it dies in the stomach
- Levitra (Vardenafil) — middle ground, less popular these days. Some lifters reach for it when sildenafil gives them the sinus headache from hell
A few peptides from @Prymal's shelf actually pull real weight in this conversation:
- PT-141 (Bremelanotide) works on melanocortin receptors, not the vascular pathway like Cialis or Viagra. Translation: it kicks in even when the blue/yellow pills are doing nothing. Direct desire and erection lever, gold for the days where the head is wired but the body is not playing along.
- Oxytocin the bonding hormone. Some lifters specifically dose it pre-deed for orgasm intensity and the after-glow connection. Niche but the fans are vocal.
Curious where the rest of you sit.
very positive news 
I am happy to be contributing!
lol 
