Cagrilintide: The experiment is for myself to try a new peptide and also see if it can be used while i reduce my dosage on Terzepatide. I started Terzepatide September of 2023. I was put on it for diabetes. It did wonders for curing my diabetes at the starting does and when i went to 5 mg. After that i started chasing having the medicine get rid of the food noise at first and I ended up at 7mg. Then at that point i learned i needed to eat protein to grow muscle and get stronger. During this time iset a powerlifting goal I wanted to reach before I turned 50 years old. If you want to learn more about that you can read my first log, https://www.evolutionary.org/forums...irzepatide-to-testosterone-anavar-log.103301/. During this time I wanted to eat and I taught myself to eat right through the medication so I could reached my powerlifting goal Aug. 9th 2025. I wanted to take a break from the bulk and try and cut. The plan was to cut and raise my medication up to start getting rid of the food noise again. I then went to 10mg, 12.5mg and 15mg and it did nothing for me. So at that point I didn't know what to do. I had been hearing from others that there is this other peptide called Cagrilintide that stops food noise through a different pathway. Then I decided I wanted to try it and while trying it I would reduce my terzepatide back down to a goal dose of 2.5mg which is the lowest dose that I can go on with my prescription of Mounjaro. This is where this experiment for myself and maybe it will help other people who end up on the max dose of GLP-1 drug and it is not working for them any longer and they want to reduce back down or get off but don't want all the food noise to come rushing back and they just get fatter then when they started the drug. I am just going to talk about my experience going through this. My concern with just cutting my glp-1 back down with out adding in a helper was that maybe the terzepatide is curbing a lot of food noise that I don't even realize and if I go down with out it the food noise all comes roaring back.
My Information:
Age: 50 years young
Height: 5' 10"
Weight: as of 5/1/26: 235 lbs
body fat%: from last inbody scan as of 4/23/26 20.6
Training experience: 2 years 6+ months
Training: I run a push, pull, legs work out 6 days a week. If you want to follow along with my training you can check out my other current log that I am updating with all my training stuff. https://www.evolutionary.org/forums...d-to-200lbs-or-less-my-first-cut-ever.106162/
Diet: It is pretty much the same thing day in and day out. Meal after training 6 eggs, 12 ounces of ground beef 90/10 and 9 ounces of white rice. Dinner is a pound of meat and some veggies if i can get them in. You will see in this log diet has changed to less food.
Supplements:
Preworkout:
10 grams of creatine mono
2.5 grams of HMB
liquid IV packet
15 grams of psyllium husk
Supplements after eating my meal after training:
Thorn Basic nutrients 2/daily
CoQ10 200mg daily
3600mg fish oil daily
Pre and probiotic 20 billion cells and 12 strains
vitamin D with k2 Mk-7 10,000 Iu/ 200mcg
Lutein and Zeaxanthin
Telemisartan-hctz 80-12.5 mg
Supplements on the way to work:
10 grams of creatine mono
2.5 grams of HMB
liquid IV packet
15 grams of psyllium husk
Supplements before bed:
Magnesium Glycinate 360 mg
PEDS and Peptides:
Testosterone Cypionate 140 mg divided into 3 shots per week
Nandrolone Decanoate 50mg divided into 3 shots per week
Mounjaro (terzepatide) 12.5 mg per week
Cagrilintide 1mg per week
GH 4iu 30 minutes before bed
Cycle Plans: I have no plans of a cycle at this time. I am currently working to find a good TRT level where my blood work is within good levels. I have high hematocrit and red blood cells as of my last blood work. You can read my current training log to find out more about that there.
Goals of this experiment: To reduce my terzepatide back down to the lowest does. While using the least amount of cagrilintide. Then once i reach the the minimum dose I plan to add 1 mg of retatrutide to the mix. If I lose weight while i go through this process that is an added benefit but not the primary goal here.
My Information:
Age: 50 years young
Height: 5' 10"
Weight: as of 5/1/26: 235 lbs
body fat%: from last inbody scan as of 4/23/26 20.6
Training experience: 2 years 6+ months
Training: I run a push, pull, legs work out 6 days a week. If you want to follow along with my training you can check out my other current log that I am updating with all my training stuff. https://www.evolutionary.org/forums...d-to-200lbs-or-less-my-first-cut-ever.106162/
Diet: It is pretty much the same thing day in and day out. Meal after training 6 eggs, 12 ounces of ground beef 90/10 and 9 ounces of white rice. Dinner is a pound of meat and some veggies if i can get them in. You will see in this log diet has changed to less food.
Supplements:
Preworkout:
10 grams of creatine mono
2.5 grams of HMB
liquid IV packet
15 grams of psyllium husk
Supplements after eating my meal after training:
Thorn Basic nutrients 2/daily
CoQ10 200mg daily
3600mg fish oil daily
Pre and probiotic 20 billion cells and 12 strains
vitamin D with k2 Mk-7 10,000 Iu/ 200mcg
Lutein and Zeaxanthin
Telemisartan-hctz 80-12.5 mg
Supplements on the way to work:
10 grams of creatine mono
2.5 grams of HMB
liquid IV packet
15 grams of psyllium husk
Supplements before bed:
Magnesium Glycinate 360 mg
PEDS and Peptides:
Testosterone Cypionate 140 mg divided into 3 shots per week
Nandrolone Decanoate 50mg divided into 3 shots per week
Mounjaro (terzepatide) 12.5 mg per week
Cagrilintide 1mg per week
GH 4iu 30 minutes before bed
Cycle Plans: I have no plans of a cycle at this time. I am currently working to find a good TRT level where my blood work is within good levels. I have high hematocrit and red blood cells as of my last blood work. You can read my current training log to find out more about that there.
Goals of this experiment: To reduce my terzepatide back down to the lowest does. While using the least amount of cagrilintide. Then once i reach the the minimum dose I plan to add 1 mg of retatrutide to the mix. If I lose weight while i go through this process that is an added benefit but not the primary goal here.
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