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Letrozone for steroid cycle support

Using Letrozone as on-cycle support, you are wasting money on steroids if you don’t.

The steroids you inject or ingest do not cause female-like side-effects on their own, the estrogen that your body makes from them is what really does it.  Every time you inject some super “frankensteroid” to get huge, chances are the aromatase enzyme in your body will attach to your steroid and turn it into some nasty girly hormone.  It is these estrogen-like hormones that will attach to your breast tissue and cause you to grow tits, or cause water retention or impotence. The only way to keep from getting girly side-effects from steroids is to stop the conversion to estrogen at the source, by inhibiting the aromatase enzyme thus keeping it from wreaking havoc on your steroid cycle.

Letrozone (LZ) is a designer transdermal agent containing Formestane, Arimistane, 11-OXO, 7,8 Benzoflavone and I3 Carbonyl. This is a full formula that is extremely effective at inhibiting the aromatase enzyme and making sure you avoid disastrous side-effects during your steroid cycle. Most notable side-effects from estrogen conversion are the dreaded bitch-tits and puffy-faced water retention.

letrozone AI

Fig 1. Letrozone Bottle

Formestane and arimistane are the two main compounds that lower estrogen by working like “suicide aromatase inhibitors,” or AI for short. A single unit of aromatase enzyme in your body can go on a rampage and turn several anabolic steroids into estrogen. The enzyme will hang out in the male breast tissue, obliques and other parts where it will wait for testosterone and other hormones to pass by.  As male hormones flow past the tissue in high enzymatic concentrations, the aromatase enzyme will attach to them one at the time and move their molecular structure around to turn them into estrogen-like hormones.  Before the enzymatic conversion took place, these steroids were tough guy male hormones looking for androgen receptors in muscle tissue where they can attach and activate cell growth.  After the same tough guy hormones have been converted by the enzyme, they become a gang of girly estrogen-like hormones that are looking out for estrogen receptors in your breast tissue telling it to grow for the baby that is coming (why else would your estrogen be this freaking high?).

A single unit of aromatase can quickly turn several testosterone molecules into estrogen, by going from one to the other, attaching, rearranging and letting go of the newly created estrogen hormones.  Once the estrogen is release from the enzyme, the aromatase unit moves on to the next testosterone molecule to cross its path, and another and another.  This is why when you inject steroids you are only giving the aromatase enzyme more substrate to work with, and the more steroid you take, the more the enzyme has to work with.  A suicide aromatase inhibitor like formestane in Letrozone works is by presenting itself as a suitable candidate to be transformed into estrogen, the aromatase enzyme takes the bait and attaches to the formestane structure, but something unexpected happens.  The formestane molecule never lets go of the enzyme; once attached, the formestane will hang on to the enzyme and not let it move on to affect other steroids, rendering the aromatase enzyme useless, leaving your steroids to roam free.  Without the aromatase enzyme there to convert your steroids into female hormones, more steroids are available for muscle growth, with less side-effect.  The magic of the suicide inhibitor is the way formestane locks the enzyme in and doesn’t let go.

Aromatase Enzyme

Fig 2. Aromatase Enzyme

The Letrozone formula doesn’t just contain the very best aromatase inhibitors a bodybuilder can buy, it also contains ingredients that display effects like those of Selective Estrogen Receptor Modulators (SERMs).  Thus, helping you keep estrogen from ever reaching the receptor sites in the first place. LZ also contain ingredients that act as progesterone/prolactin reducers, which are very important to keep your penis hard and working.  High progesterone and prolactin levels will cause you to have a flaccid penis almost immediately, and Letrozone contains ingredients to help deal with both hormones.

The designer prohormone in Letrozone called formestane converts to 4-hydroxytestosterone, this is a very anabolic agent when applied at higher dose.  The conversion of formestane to 4-hydroxytestosterone creates a new steroid with an anabolic/androgenic ratio comparable to that of the steroid primobolan depot. Aside from converting to a very strong steroid, formestane increases IGF-1 levels by more than 28%.  Formestane, along with the other ingredients in Letrozone, are sure to boosts your natural HPTA and overall testicular activity, much like a combination of HCG and Aromasin.

prolactin hpta

Fig 3. HPTA Diagram

The formestane in Letrozone is not just any prohormone, this powerful designer agent was a prescription drug in the United States and still remains a prescription drug in many countries.  In fact,  it is still sold under the pharmaceutical brand name Lentaron I.M. Depot®.  When compared to other AIs used for the same purpose, like aromasin or arimidex, formestane was deemed “too anabolic,” which lead the US government to ban Lentaron I.M. depot® from medical use.  Aromatase inhibitors like arimidex and aromasin work in the very same way by keeping estrogen low; however, formestane has the added effect of converting to a powerful steroid in your body.

In conclusion, formestane works as a powerful aromatase inhibitor and is just as strong at reducing estrogen as aromasin or arimidex could ever be, but it was its secondary anabolic effect that caused its medical application to be discontinued.

To use Letrozone as an on-cycle support and shut-down prevention agent, apply 4ml of the product to your chest and oblique area every 12hrs.


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Written by
Albert Wolfgang is a professional medical writer with over 20 years of experience. He hold multiple personal training certifications, including the coveted NASM and AFAA certificates. He graduated with honors with a B.S. and M.S. in biochemistry with a minor in physical studies. Albert and his team have trained over 100 IFBB professional bodybuilders, including Hollywood stars and many up and coming fitness stars.

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