Just wanted to post up some musings about how GLP-1's and fasting have completely destroyed the concept of IIFYM. This should have never been a debate in the first place but there are some very stubborn people out there who insisted that IIFYM (if it fits your macros) was a legitimate diet idea. They based this on hormones in the body did not matter. it was all about just calories in/out that determined weight gain/loss. this means you can eat every 2 hours, eat pizza, fast food, mcdonalds, subs, and all that other crap and not worry about a thing since at the end of the day just like were were robots its all about cals in/out. I've always argued that you can calculate calories in to some degree, but calories out and hormonal changes (which both CANNOT be calculated accurately on a day to day basis or even week to week basis) in the body will ultimately determine fat gain or loss. We see this example with weight watchers where people count points and eat in a deficit and fail to lose weight, in fact many GAIN weight following those types of calorie counting diets.
anyway we've seen guys like Dr. Jason Fung argue that hormones play a huge role in fat gain or loss and how fasting helps change your bodies fat burning abilities by improving insulin sensitivity. Now I don't agree with EVERYTHING he advocates however on this particular topic he has been proven 100% accurate and I never doubted him for a second because he always backed his shit up with HUMAN STUDIES without bias. It was always amazing to see guys like Layne Norton, Milos Sarcev and other meathead online gurus attack those people and call them wrong without a shred of scientific evidence. Of course these guys can lift heavy ass weights and look like huge bodybuilders so they must be smarter then a geeky looking guy in glasses right? It's just 'trust me bro' mentality. It makes me sick to know how much BETTER these guys could look if they listened to the science and how much better the people they coach could look.
Well if these GLP'1's aren't evidence of who is right and who is wrong then at this point you can chalk up enlarged ego and ignorance on these folks. You see, you can eat the SAME FOODS and take GLP'1's and STILL LOSE BODY FAT. why? cause they effect your hormones in the body. OR you can already be eating perfect for years and not get good results, but then go on a GLP-1 and implement fasting and have terrific results in a short time period.you can also STOP taking the GLP-1's and STILL EAT THE SAME WAY and GAIN FAT BACK!! yes the studies show this and we have seen the anectodal evidence of this. So our bodies ABSOLUTELY are effected by hormones. The same logic as to why pregnant women GAIN tons of fat/weight during pregnancy even if they eat the same diet, their hormones change! the same reason they produce milk like magic too. hormones PLAY A HUGE ROLE. same reason if you run a ton of dbol and test and don't use an AI you too can have lactating nipples. HORMONES ARE IMPORTANT and ignoring them and pretending they don't matter is a huge roadblock to your sucess.
Retatrutide does 3 things as a triple agonist which I go in detail on my podcast
https://www.evolutionary.org/evolut...de-benefits-and-new-studies-by-geneza-pharma/
the 3 things are:
1. GLP-1 of course which regulates insulin secretion and appetite (exactly what Dr. Jason Fung has been saying for YEARS to some deaf ears)
2. GIP which improves glucose and lipid metabolism (exaclty what time restricted fasting and long term fasting accomplishes)
3. GCG which effects glucagon (glucagon will rise during a fasted state while insulin drops) This effects how energy is expended and puts you into a fat burning mode.
when you eat in a time restricted window, implement fasting AND add retaturide to the mix you put your body into a fat burning mode WITHOUT the nasty side effects found in other fat burning drugs. Insulin is controlled and glucagon is humming right along. It is truly the best way to burn fat in 2025. The magic formula is here.
Now I'm seeing these meatheads putting out videos admitting that GLP-1's work, but now their logic is still assinine. They claim it only works because people eat
less on them which is 100% innacurate. people in the studies
ATE THE SAME WAY. The placebo group lost 1% of body weight, the Retatrutide group lost 20%. and then the Retatrutide group who came off who also kept the SAME DIET gained weight back. Listen to the podcast where I expalin the studies in depth. it is a never ending cycle of stupidity and ignorance with these people SMH. They will never admit they were wrong no matter what.
The lesson is when it comes to this stuff listen to the people who bring the science and not the people who bring the bro science.