DNP is a compound specifically designed (if in crystalline form) to poke holes in the ETC (electron transport chain) of the mitochondria. The ETC is also known as the Respiratory Assembly of Mitochondria. Essentially, by popping holes in the ETC, you lose hydrogens to the lumen that would normally be used by ATP hydroxylase to convert ADP to ATP. By doing this, you lose energy and force the mitochondria to work harder to make up for the loss of protons. Eventually the body realizes that the mitochondria it has are overworked, so it creates more mitochondria. You know what it takes to make mitochondria? Yup, ATP. So while making more Mitochondria, your body is working even harder to pump out enough ATP. Also, I'd like to note that the major factor that differentiates Unilocular (white) adipose tissue from Multilocular (brown or fetal) adipose is the fact that brown fat naturally does not have the respiratory assembly and thus works purely for heat production due to the fact that babies are unable to generate heat from muscle development used in adults (shiver muscles). So, DNP basically makes the normal mitochondria of white fat, work like the modified mitochondria of brown fat. In this way, it affects the "respiratory system". Now, if you are NOT taking true pharmaceutical DNP in crystalline form, you are taking its chemical cousin, yellow powder DNP. This was never meant to be ingested but was actually used as an igniter for fireworks and other explosive ordinance as well as being used as a powerful pesticide. However, this compound will ABSOLUTELY fuck with your cardiovascular system as it has a very high affinity for cardio myocytes (heart muscle cells). Crystalline has this same affinity but is packaged differently so that it does not accumulate in the heart (basically it has a very specific lipid profile modification in order to carry it inside special vesicles that prevent it from being identified until it is absorbed into the membranes of cells in tissue which makes it too late for it to be repackaged and sent back to the heart since it will already be close enough to the mitochondria of whatever tissue it is in. So, with all that being said, make sure you're not taking a powder used for TNT fuses. Find a legitimate source like DiNitro and get the actual pharmaceutical lab grade crystalline DNP.