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would love to get in on the retatrutide party. I’ve read so many different people having great results on this stuff. How much do you recommend I run? Should I go with 1-2mgs a week? Or would I be able to run it more like 4-5mgs a week? I’m 320 lbs and I would like to lose 100 lbs.
1mg/wk is the correct starting dosage. More is not better. You still need to out I the work.
Heck out our articles and podcasts. We’ve covers this topic many times.
Reta will be perfect for your goals brother. My opinion it just start at 1mg single weekly dose for a couple of weeks and see how your body responds. If you dont get negative side effects and appetite suppression is clear then continue at that dose until the suppression starts to fade andthen increase to 2mg and repeat the process.
Dont jump the gun too early and go big doses. Its not needed and will just leave you feeling like shit and wasting money.
Just get the most out of ever dose increase and any additional exercise will always be a huge benefit. Good luck brother
LevButlerov
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1mg/week to start slow
1mg/week to start. Let it build up because you won't know you have issues until it's too late to cut back. If you wanna lose 100lbs you have all the time in the world to get up to 4-5mg.
You'll need to start a log so we can add fuel to the fire and get your diet and any training you do in check with the retatrutide. See below.... for example you could call yours "My 100lb weight loss journey with Retatrutide"
HOW and WHY TO LOG?
Why is a Log Journal important?
Accountability, pride, and consistency all which lead to RESULTS!
Authoring a log will actually help you way more than just dropping random updates. When you lay it all out week by week you start to see patterns in your body that you won’t catch otherwise.
Other guys here run logs all the time and there’s no privacy issue, nobody is asking for your name or anything personal, it is just training, diet, and how the compound feels.
The feedback you get is also way better because people can follow along and spot things you might miss. It also helps the next guy who is thinking about running the same compound so you are giving back while you learn.
Even if you think you might not stick with it, just starting the log makes it easier to come back and add quick notes. That way you get more out of what you are running instead of keeping it all in your head.
To really guide you we need more info from you:
Please share your diet, training, cardio, sleep, supplements etc log with us in a NEW thread using a full log journal so our guidance is based on facts you provide.
It will take 15-20 minutes max.
We have 100's of years of experience between us, so you need to post a LOG Journal with your stats (weight, height, age, years training, cycle history) diet, training, cardio, supplement, sleep details. If you don't log what you eat or train now, open NOTES on phone and start recording it there and paste here. Very easy.
Please post a Log Journal ASAP for us
There are almost a quarter million members on here and almost two million posts with over a thousand podcasts so your Log Journal will be taken care of here! Evolutionary.org is the most visited steroid community in the world (fact!).
Here's how:
Please click the anabolic forum
https://www.evolutionary.org/forums/forums/anabolic-steroids-and-peds.2/
top RIGHT you will see: +POST THREAD
click that
In Title: write your cycle name, like> My _____ Cycle Log
___ = the name of your log
example: My testosterone cycle Log
In body: write your planned cycle or cycle you doing now, your diet, training, your body weight, supps, etc and we will help you along on your cycle or help you decide when it's time.
For example: What are your supplements?
what digestive supps you use?
digestive enzymes?
multis?
probiotics?
psyllium husk?
Here are examples of LOG Journals you can choose to use as your template:
https://www.evolutionary.org/forums/threads/first-testosterone-cycle-log.104133/
https://www.evolutionary.org/forums/threads/sustanon-trenomast-deca-dbol-cycle-journal.105881/
https://www.evolutionary.org/forums/threads/s-gentz-2025-26-growth-phase-log-with-psl.106514/
https://www.evolutionary.org/forums...var-bpc157-beligas-pharmaqo-cycle-log.104843/
https://www.evolutionary.org/forums...g-log-sponsored-by-purity-source-labs.103669/
https://www.evolutionary.org/forums...erone-cycle-and-beginner-training-log.106310/
https://www.evolutionary.org/forums/threads/average-trt-back-to-savage-cycle-journal.106252
https://www.evolutionary.org/forums...-testosterone-masteron-primobolan-deca.105348
https://www.evolutionary.org/forums...odybuilding-log-masters-55-competitor.102611/
https://www.evolutionary.org/forums...ron-npp-tren-anadrol-log-to-stage-2025.102590
P.S. are you listening to our podcast? if not, you should. This podcast is about steroids, sarms, peptides, and bodybuilding:
https://www.evolutionary.org/podcasts/
https://podcasts.apple.com/us/podcast/evolutionary-bodybuilding-radio/id1798623410
https://open.spotify.com/show/53q1RFTgG4h6TQHsJ4xY6Z
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@Poabeui Pretty clear advice here to start at 1mg did you decide on starting a log with us?
It is safe if dosing transition is done correctly.
LevButlerov
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in theory its safe but in practice it depends on the person @ratesy why do you want to switch? tell us more
we can help you
Retatrutide works by activating three pathways—GLP-1, GIP, and glucagon receptors—which together suppress appetite, improve insulin sensitivity, and increase energy expenditure. That’s why the protocol emphasizes slow titration: starting low (around 1–2 mg weekly) lets your body adapt to the strong appetite and GI effects, then gradually increasing every few weeks helps avoid common issues like nausea, reflux, or fatigue. Unlike older GLP-1 drugs, Retatrutide’s glucagon activity can raise metabolism, so weight loss can be more aggressive—but that also increases the risk of muscle loss if calories or protein are too low. In practice, people aim for a steady rate of fat loss while keeping protein high and resistance training consistent. Another key point is staying at the lowest effective dose—once appetite is controlled and weight is trending down, there’s usually no need to keep increasing, since higher doses mainly increase side effects rather than dramatically improving results.
Retatrutide is typically used with a gradual dose-escalation protocol to minimize side effects while maximizing fat loss and metabolic effects. Most approaches start very low (e.g., ~1–2 mg once weekly), then increase every 3–4 weeks (such as 2 → 4 → 6 → up to ~8–12 mg weekly) depending on tolerance, appetite suppression, and side effects like nausea or fatigue. The goal is slow titration rather than rushing to a high dose, since its triple-agonist activity is potent. It’s usually paired with a calorie-controlled diet and adequate protein to preserve muscle, and users often stay at the lowest effective dose that maintains appetite control and steady weight loss rather than pushing maximum dosing.
Retatrutide is typically used with a gradual dose-escalation protocol to minimize side effects while maximizing fat loss and metabolic effects. Most approaches start very low (e.g., ~1–2 mg once weekly), then increase every 3–4 weeks (such as 2 → 4 → 6 → up to ~8–12 mg weekly) depending on tolerance, appetite suppression, and side effects like nausea or fatigue. The goal is slow titration rather than rushing to a high dose, since its triple-agonist activity is potent. It’s usually paired with a calorie-controlled diet and adequate protein to preserve muscle, and users often stay at the lowest effective dose that maintains appetite control and steady weight loss rather than pushing maximum dosing.
Consider domestic-supply.com
LevButlerov
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Head Moderator
Raptor Labs VIP
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how much you plan to save? retatrutide is more expensive @ratesy
