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Community Research SLU-PP-332 Peptide - Administration Routes, Dosing, and Reviews

Threads marked with the 'Community Research' prefix involve ongoing research, high-quality logs, or in-depth community discussions backed by experience, data, or expert input.
This all in theory it may not crash out when you mix or inject. Even if it does it will just release slower then anticipated. Some drugs are actually designed to crystalize so that they do slow absorb. I want to try this because it sounds like worse case scenario I will get an irritation. Without proper equipment it's hard to say what really happens. I have heard another guy who is a doctor say that they are making it stable before injection with dmso so it sounds like it can stay stable when it gets diluted. The question is will it stay stable with peg. I guess I won't know until I try it and see if it looks like it stays stable. I guess stay tuned as I learn more and try it. I like the idea of using peg now over dsmo. I wonder if someone already tried peg already and it didn't work and that's why they been using dmso. The benefits of slu-pp-332 out way the negatives of dsmo and that's why they use it.
What are the negatives of dmso? I thought it was used to allow for transdermal absorption
 
My understanding is that there isn’t any anecdotal data that I could find of people actually injecting DMSO (maybe a few but nothing of substance) whereas there are some vendors selling SLUPP already suspended in MCT oil with a whole megathread of positive feedback that I’ve read and pointed out to me by @CladHQ.

I think I’m just gonna stick to filtered MCT for now for at least the first vial until we continue to discuss this and figure out the best route.

Can we figure out the polarity of SLUPP and try and find a closely matching polarity carrier that isn’t DMSO?

I like your brain @kcates between you, me, @Shakey and @LevButlerov we might be able to find a better suited carrier than MCT.
Hey will you point the mega thread out to me as well. I like to read about others experience with that combo. If it works it works. Things I am pointing out is just based on the scientific rules. I heard a guy today say they been using it transdermal using dsmo.
 
At present just using 1mg x 3 times a day of UGLOZ Slupp332. Soon to be released and 10mg of MB. Working an absolute treat.

Screenshot_20251120_225823_Gallery.webp
 
My understanding is that there isn’t any anecdotal data that I could find of people actually injecting DMSO (maybe a few but nothing of substance) whereas there are some vendors selling SLUPP already suspended in MCT oil with a whole megathread of positive feedback that I’ve read and pointed out to me by @CladHQ.

I think I’m just gonna stick to filtered MCT for now for at least the first vial until we continue to discuss this and figure out the best route.

Can we figure out the polarity of SLUPP and try and find a closely matching polarity carrier that isn’t DMSO?

I like your brain @kcates between you, me, @Shakey and @LevButlerov we might be able to find a better suited carrier than MCT.
I would either go sublingual or oral with slupp 332 I dont see the need to inject it unless you really want to experiment :D @HarleyGuy
worst case we can have mct tbsp with the capsule as it's being taken orally to help with absorption but I still think sublingual is the way
 
At present just using 1mg x 3 times a day of UGLOZ Slupp332. Soon to be released and 10mg of MB. Working an absolute treat.

View attachment 198404
Absolute HULK MODE brother @Pigsy !! Look at those mitts on you you could crush my skull with one hand! I wish my flaccid johnson was the size of just your thumb FFS!
 
I would either go sublingual or oral with slupp 332 I dont see the need to inject it unless you really want to experiment :D @HarleyGuy
worst case we can have mct tbsp with the capsule as it's being taken orally to help with absorption but I still think sublingual is the way
Sublingual will be the way then! Assuming I can pop the SLUPP vials and sublingual the peptide directly. 1/5th of 5mg is 1mg so about 1/5th of the vial? This may or may not be a very stupid question as I don't know what the dimers are (but don't care unless you say to care LOL :p)
 
Sublingual will be the way then! Assuming I can pop the SLUPP vials and sublingual the peptide directly. 1/5th of 5mg is 1mg so about 1/5th of the vial? This may or may not be a very stupid question as I don't know what the dimers are (but don't care unless you say to care LOL :p)
yes that would be 1/5 :D and there are no stupid questions we are all here learning and growing brother :D @HarleyGuy
 
yes that would be 1/5 :D and there are no stupid questions we are all here learning and growing brother :D @HarleyGuy
Haha no bro the math I'm good with, it was more going sublingual straight out of the peptide vial being safe or not... I'll carefully split it into fifths and under-the-tongue it after dumping it out on a controlled surface. Was just wondering if ordering the raw powder would be better or if straight from the vial is fine too :p

I did reconstitute a vial of @biogenix SLUPP with bac water just for a pic for this research thread of what SLUPP looks like in bac water. I'll put it in my log too.


14Mar Bio SLUPP recon.webp
 
Haha no bro the math I'm good with, it was more going sublingual straight out of the peptide vial being safe or not... I'll carefully split it into fifths and under-the-tongue it after dumping it out on a controlled surface. Was just wondering if ordering the raw powder would be better or if straight from the vial is fine too :p

I did reconstitute a vial of @biogenix SLUPP with bac water just for a pic for this research thread of what SLUPP looks like in bac water. I'll put it in my log too.


View attachment 198534
this actually looks clear :D you added sterile MCT? @HarleyGuy
 
@Wookie shared his doses of SLUPP 332 use in his log
https://www.evolutionary.org/forums...le-log-sponsored-by-ugloz.106847/post-2009513
For the slu im doing 20mg three times a day. Morning, Lunch and Pre-workout. I have had higher doses 140mg-200mg but for me i found it affected my cardio, almost a feeling of cant be bothered doing it thing. Where as with the lower dose its a different mindset and effortless. If I start reading some posts on forums or start filling out my log, before I know it 30-40mins is gone
 
this actually looks clear :D you added sterile MCT? @HarleyGuy
No no this was just BAC water... we were discussing in my log that SLUPP was thought to reconstitute milky in BAC and it reconstituted clear which is weird and I thought it best to do with BAC for community research and maybe figure out why. Now I have 5mg of SLUPP in BAC water and not sure what to do with it, maybe just pin it all LOL.
 
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I've switched it up to 4mg sublingual (2mg x 2) ED since mine are tablets. Has any of our SLUPP enthusiasts tried sublingual?

I have SLUPP peptide in vials for subQ injection as well and I'll be doing sublingual with that too. Thoughts?
I've got approximately 10 caps left then will try sublingual for a week
 
I'm up to 90 as of today, absolutly no sweating no fatigue. Absolutely no side effects at all.
Ok this is interesting, thanks for advising bro. I've read on here some major fatigue when pushed upwards of 100mg, I think it was @Allupfromhere that noticed this.
 
I've got approximately 10 caps left then will try sublingual for a week
This is awesome @Grumpy. If we can find a way to get some anecdotal data that sublingual works it might mitigate the fear surrounding the idea that SLUPP doesn't survive the stomach and give our bros another option.
 
Ive just started using it at 2mg first thing in the morning and im finding instantly my body feels hotter, Im sweating more during my morning cardio but im also experiencing some slight tiredness/lethargy.

Could just be from comp prepping in general, but definitely feeling it at this dose for half the day.

Will monitor how i feel this week 🤷‍♂️

Taken orally aswell 2mg/ml liquid mix
 
This is awesome @Grumpy. If we can find a way to get some anecdotal data that sublingual works it might mitigate the fear surrounding the idea that SLUPP doesn't survive the stomach and give our bros another option.
Very true also really interested to know this myself so will be a good experiment
 
Ive just started using it at 2mg first thing in the morning and im finding instantly my body feels hotter, Im sweating more during my morning cardio but im also experiencing some slight tiredness/lethargy.

Could just be from comp prepping in general, but definitely feeling it at this dose for half the day.

Will monitor how i feel this week 🤷‍♂️

Taken orally aswell 2mg/ml liquid mix
I felt the tiredness lethargy for the first 3 to 4 days then seemed to pass
 
I've switched it up to 4mg sublingual (2mg x 2) ED since mine are tablets. Has any of our SLUPP enthusiasts tried sublingual?

I have SLUPP peptide in vials for subQ injection as well and I'll be doing sublingual with that too. Thoughts?
Hey mate! Haven’t seen any slu tabs kicking around through our Aussie vendors. Just the caps and injectable.
Can I also get all our brothers to point out any side effects on SLUPP on their dose? ie: sweating, fatigue?

So this is an interesting one as I have had great success with my workouts and results at 500mcg to 2mg. I found 20mg as my upper limit and I am going extremely well at that dose. By mid week though, I start to run into some mid-afternoon fatigue (which I can still power through with no issues).

When I experimented with 40mg pre workout, I found myself on the couch, having a nap to sleep off severe fatigue, and haven’t revisited those higher doses since the first time.

I don’t notice any other side effects such as sweating etc. well, a bit hard to say, as I train in humidity and sweat a bucket load… and when I do train in air-conditioning, it’s just the usual sweat one would expect 🤷🏻.
 
Ive just started using it at 2mg first thing in the morning and im finding instantly my body feels hotter, Im sweating more during my morning cardio but im also experiencing some slight tiredness/lethargy.

Could just be from comp prepping in general, but definitely feeling it at this dose for half the day.

Will monitor how i feel this week 🤷‍♂️

Taken orally aswell 2mg/ml liquid mix
Thanks so much for hopping onto this research thread @AusMade I've added you to the original research post of EVO users for SLUPP.

This is some amazing feedback from both the low dosing camp of EVO brothers as well some anecdotal feedback for oral dosing and NOT in any type of pill form but instead a liquid mix.

Two questions
1. Do you know if it's carried in BAC water as it's liquid?
2. Do you swallow it or let it sit in the mouth a bit to get some sublingual absorption?
 
Hey will you point the mega thread out to me as well.
@kcates did you mean the megathread sent to me by @CladHQ regarding the SLUPP product suspended in MCT oil and the megathread discussing that?

Very true also really interested to know this myself so will be a good experiment
Me too! Keep us posted!

I felt the tiredness lethargy for the first 3 to 4 days then seemed to pass
I had this too as well as a facial flush in my cheeks at only 2mg and it's gone away now as well.
 
Hey mate! Haven’t seen any slu tabs kicking around through our Aussie vendors. Just the caps and injectable.

So this is an interesting one as I have had great success with my workouts and results at 500mcg to 2mg. I found 20mg as my upper limit and I am going extremely well at that dose. By mid week though, I start to run into some mid-afternoon fatigue (which I can still power through with no issues).

When I experimented with 40mg pre workout, I found myself on the couch, having a nap to sleep off severe fatigue, and haven’t revisited those higher doses since the first time.

I don’t notice any other side effects such as sweating etc. well, a bit hard to say, as I train in humidity and sweat a bucket load… and when I do train in air-conditioning, it’s just the usual sweat one would expect 🤷🏻.
This is some great feedback brother thank you! This lends to the theory I heard on a very reputable podcast that SLUPP is one of those peptides that works well in the mcg dosing ranges and any more than that causes a negative feedback loop where it causes a 'backlog' and starts behaving like an uncoupler hence causing the fatigue and sweating we've seen others post already as their feedback.
 
Can I also get all our brothers to point out any side effects on SLUPP on their dose? ie: sweating, fatigue?

I’ve had no obvious sides @ 20mg PWO. I train 5.30am, take SLU around 4.30am and have no crash or fatigue throughout the entire day.

In fact, together with Mots C I’ve been getting through the days fairly comfortably with good energy. Typically won’t finish up gym / work / parent duties until 9pm by the time I sit on the couch to put feet up.

Yet to try SLU without Mots C just yet.
 
I’m finding I get quite thirsty but that could possibly be the Reta as well as just started that the same time??
Interesting. If the SLUPP is creating heat for you like it does for some with the warmth and sweating it could be the cause of the thirst. I haven't heard about increased thirst with Reta I don't believe.
 
I’ve had no obvious sides @ 20mg PWO. I train 5.30am, take SLU around 4.30am and have no crash or fatigue throughout the entire day.

In fact, together with Mots C I’ve been getting through the days fairly comfortably with good energy. Typically won’t finish up gym / work / parent duties until 9pm by the time I sit on the couch to put feet up.

Yet to try SLU without Mots C just yet.
Yes so far the feedback has been an avoidance of that proverbial 'crash' in the afternoons using SLUPP. I'm sure the MOTS-C is helping with this as well. Ironically I think MOTS-C will be the next research article for peptides so stay tuned and thanks for the feedback!

I only sleep about 4-6 hours and then nap about 2 hours a day either by one long full sleep cycle nap or two to three 45-min naps so I have no feedback on SLUPP getting me through the day in this sense but this seems promising for those that have that 2pm crash.
 
Ok this is interesting, thanks for advising bro. I've read on here some major fatigue when pushed upwards of 100mg, I think it was @Allupfromhere that noticed this.
I did notice an increase in sweating during cardio while using SLU. That’s actually fairly consistent with what we would expect from a compound that enhances mitochondrial activity and overall metabolic output.

The fatigue I experienced, however, I wouldn’t attribute solely to SLU. At that stage I was extremely lean, calories were low, and mitochondrial upregulation was already very high from the combination of training, dieting, and other metabolic agents.

When mitochondrial activity is pushed higher, the cells are essentially being encouraged to increase energy turnover. But ATP production is still ultimately limited by substrate availability.

If fuel sources like glucose, glycogen, and fatty acids are scarce due to low caloric intake and very low body fat levels, there is only so much ATP that can actually be generated.

In that scenario you can end up in a situation where metabolic demand is being driven upward, but the available energy substrates cannot fully support that demand.

The result can be a noticeable increase in fatigue, reduced performance, and a general sense of energy depletion despite mitochondrial pathways being highly active.

So in my view, the fatigue was more likely the result of pushing mitochondrial output in an already fuel-restricted state rather than the effect of SLU in isolation.
 
I did notice an increase in sweating during cardio while using SLU. That’s actually fairly consistent with what we would expect from a compound that enhances mitochondrial activity and overall metabolic output.

The fatigue I experienced, however, I wouldn’t attribute solely to SLU. At that stage I was extremely lean, calories were low, and mitochondrial upregulation was already very high from the combination of training, dieting, and other metabolic agents.

When mitochondrial activity is pushed higher, the cells are essentially being encouraged to increase energy turnover. But ATP production is still ultimately limited by substrate availability.

If fuel sources like glucose, glycogen, and fatty acids are scarce due to low caloric intake and very low body fat levels, there is only so much ATP that can actually be generated.

In that scenario you can end up in a situation where metabolic demand is being driven upward, but the available energy substrates cannot fully support that demand.

The result can be a noticeable increase in fatigue, reduced performance, and a general sense of energy depletion despite mitochondrial pathways being highly active.

So in my view, the fatigue was more likely the result of pushing mitochondrial output in an already fuel-restricted state rather than the effect of SLU in isolation.
This is so well articulated and you convinced me. In laymans terms this is where the fatigue comes from because it's like having a suped up engine on nitrous then asking for more fuel when all you have in the tank is shit gas and barely any of it! So the engine is on fire raring to go but it doesn't have the fuel to supply the demand, hence causing engine fatigue.

Given this explanation which is hard to argue against it's almost then our duty of care to advise brothers not to push high doses during a cut (or prep) when cardio and training is high while in a depleted state when energy substrates are limited.

Do correct me if I'm wrong on this analogy or the leap in linking high dose SLUPP being riskier during a cut/prep in depleted states.
 
This is so well articulated and you convinced me. In laymans terms this is where the fatigue comes from because it's like having a suped up engine on nitrous then asking for more fuel when all you have in the tank is shit gas and barely any of it! So the engine is on fire raring to go but it doesn't have the fuel to supply the demand, hence causing engine fatigue.

Given this explanation which is hard to argue against it's almost then our duty of care to advise brothers not to push high doses during a cut (or prep) when cardio and training is high while in a depleted state when energy substrates are limited.

Do correct me if I'm wrong on this analogy or the leap in linking high dose SLUPP being riskier during a cut/prep in depleted states.
No, I wouldn’t necessarily frame it as dangerous. I just think from experience there can be a practical ceiling to how much mitochondrial upregulation can be beneficial when multiple pathways are being pushed at once.

Compounds that enhance mitochondrial activity can absolutely help extract more usable energy from the substrates available.

But during a cut or prep, especially when body fat, calories, and glycogen are already low, those substrates become limited.

In that state, stacking multiple mitochondrial or metabolic enhancers may still increase cellular demand for ATP, but the fuel required to sustain that demand simply isn’t as available. So instead of improving output, you can reach a point where fatigue becomes the limiting factor.

So the compounds themselves aren’t necessarily risky in isolation. It’s more that when energy availability is already constrained, there appears to be a ceiling where further pushing mitochondrial activity stops being constructive and just accelerates depletion.
 
This is awesome @Grumpy. If we can find a way to get some anecdotal data that sublingual works it might mitigate the fear surrounding the idea that SLUPP doesn't survive the stomach and give our bros another option.
Mine are in enteric caps so should be passing through the stomach and being dissolved/absorbed in the intestines.
As for sides I notice increased sweating while doing cardio only. If my doses go higher than 100mg I notice a gyno type flair up in the left nipple area. Unsure if its a pre pubescent gyno or gear related.
My wife takes 20mg once a day and she complains of being hot, BMR increase.
Ive also noticed for my self anything from about 140mg onwards I find its counter-productive to cardio, as in i couldn't be bothered doing it vs the lower dose of 60mg where its a breeze to power through. The higher dose may have other benefits at a cellular level but thats not something I can feel or comment on.
 
No no this was just BAC water... we were discussing in my log that SLUPP was thought to reconstitute milky in BAC and it reconstituted clear which is weird and I thought it best to do with BAC for community research and maybe figure out why. Now I have 5mg of SLUPP in BAC water and not sure what to do with it, maybe just pin it all LOL.
That's odd did you talk to @biogenix about it or its not his brand? :D @HarleyGuy
 
No no this was just BAC water... we were discussing in my log that SLUPP was thought to reconstitute milky in BAC and it reconstituted clear which is weird and I thought it best to do with BAC for community research and maybe figure out why. Now I have 5mg of SLUPP in BAC water and not sure what to do with it, maybe just pin it all LOL.
Ill test it for you if your not sure what to do with it. lol
 
Great post @HarleyGuy about slu-pp-332.

I’m just adding slu-pp-332 to the list in the oral option, but I’ve also been testing the injectable version, which is based on MCT, and it looks promising 🙂

So I will most likely add it to the list soon as well.

But I have a question for everyone: what dosage per 1 ml would you like to see for the injectable option?

The oral version has 500 mcg, so I’m curious what you think.

Thanks for the post!
Best regards.

@trenAMP @Nood @RawCutlery @liftedlivingwithlegacy
@BigVelvetG @MarkNV @eazy_ @Neuro @LevButlerov
@US-pharmacies
 
Great post @HarleyGuy about slu-pp-332.

I’m just adding slu-pp-332 to the list in the oral option, but I’ve also been testing the injectable version, which is based on MCT, and it looks promising 🙂

So I will most likely add it to the list soon as well.

But I have a question for everyone: what dosage per 1 ml would you like to see for the injectable option?

The oral version has 500 mcg, so I’m curious what you think.

Thanks for the post!
Best regards.

@trenAMP @Nood @RawCutlery @liftedlivingwithlegacy
@BigVelvetG @MarkNV @eazy_ @Neuro @LevButlerov
@US-pharmacies
It would be easier to release an oral version to start tbh @US-pharmacies just get the dose higher
as you were posting this I was posting in your thread :D commenting on mg/tab

https://www.evolutionary.org/forums...-and-us-domestic-shipping.109549/post-2010552
Ment is oldschool will be interesting how it gets popular :D @US-pharmacies

the slupp 332 is going to be huge but if you can do 1mg/tab go for it, if not stick to 500mcg
we have a mega thread on SLU now https://www.evolutionary.org/forums...inistration-routes-dosing-and-reviews.109779/
Though looking at it now you can always offer 2 choices.

slu pp 332 500mcg/cap
slu pp 332 10mgs/cap
different doses for different individuals :D just a thought.
 
It would be easier to release an oral version to start tbh @US-pharmacies just get the dose higher
as you were posting this I was posting in your thread :D commenting on mg/tab

https://www.evolutionary.org/forums...-and-us-domestic-shipping.109549/post-2010552

Though looking at it now you can always offer 2 choices.

slu pp 332 500mcg/cap
slu pp 332 10mgs/cap
different doses for different individuals :D just a thought.
We’ll need to make some changes :) Thank you
 
Great post @HarleyGuy about slu-pp-332.

I’m just adding slu-pp-332 to the list in the oral option, but I’ve also been testing the injectable version, which is based on MCT, and it looks promising 🙂

So I will most likely add it to the list soon as well.

But I have a question for everyone: what dosage per 1 ml would you like to see for the injectable option?

The oral version has 500 mcg, so I’m curious what you think.

Thanks for the post!
Best regards.

@trenAMP @Nood @RawCutlery @liftedlivingwithlegacy
@BigVelvetG @MarkNV @eazy_ @Neuro @LevButlerov
@US-pharmacies
Slupp will be an amazing add to our list! Excited to give it a try 🔥
 
Mine are in enteric caps so should be passing through the stomach and being dissolved/absorbed in the intestines.
As for sides I notice increased sweating while doing cardio only. If my doses go higher than 100mg I notice a gyno type flair up in the left nipple area. Unsure if its a pre pubescent gyno or gear related.
My wife takes 20mg once a day and she complains of being hot, BMR increase.
Ive also noticed for my self anything from about 140mg onwards I find its counter-productive to cardio, as in i couldn't be bothered doing it vs the lower dose of 60mg where its a breeze to power through. The higher dose may have other benefits at a cellular level but thats not something I can feel or comment on.
Excellent feedback @Wookie. It looks like the side effect of increased body temp is definitely one that is almost across the board. Great feedback too on the different dosing and it's related side effects both good and bad.
 
That's odd did you talk to @biogenix about it or its not his brand? :D @HarleyGuy
I did yes and he hadn't had a lot of client feedback on it regarding recon appearance. We discussed solubility and I decided on the MCT oil to which I'll be reconstituting it with (after filtration). I'll be providing updates as to solubility in MCT with pics here on this research thread.
 
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wow what a study! interesting you found this just read it over @HarleyGuy
Thanks bro! I read that a while ago and been hanging onto it. It never came up until today but it's been on my list as another community reserach thread for info for EVO members.
 
@HarleyGuy - have you started running slu with oil?
I just reconstituted it with filtered C8 MCT oil this morning and I'm going to wait an hour for it to dissolve and then post results here. Haven't started running it yet no. It doesn't seem to be dissolving in MCT as the oil is just sitting on top so I'm thinking your source that sells it as a product in oil must add EO or some other compound for solubility. I'll know more in an hour or two. I'm trying to give them time to inter mingle without shaking the shit out of it LOL
 
perfect SLU dose layout I see from 1mg to 140mgs this is going to be interesting :D @HarleyGuy
Yes I missed a few members who were running it and added 3 to the list last night (well, technically this morning at 02:00 :p) so now we have 1mg all the way to 140mg, this is great! Right now I have 2mg of sublingual tabs under the tongue:p
 
but I’ve also been testing the injectable version, which is based on MCT, and it looks promising 🙂
So far my MCT isn't dissolving in my @biogenix SLUPP so is there anything else you added like EO?
 
SLUPP Solubility with MCT Oil Experiment - Process and Results




Process:
  • 5mg vial of SLU-PP-332 sponsored by @biogenix
  • Draw and filter until a total of 2ml of MCT oil is obtained using a PES 0.22nm filter
  • Backload the 2ml of filtered MCT oil into a new syringe for reconstitution
  • Load vial of SLUPP with the 2ml of filtered MCT oil for reconstitution


15Mar SLUPP experiment 2.webp
15Mar SLUPP experiment 3.webp
15Mar SLUPP experiment 4.webp
15Mar SLUPP experiment 5.webp
15Mar SLUPP experiment 8.webp





Observations:


  • Upon loading with MCT oil the oil sat on top of the peptide puck as seen in pic
  • The oil was swirled in the vial every 5 minutes
  • After time t = 1 hour the oil was still seen sitting on top of the SLUPP peptide with no dispersion

15Mar SLUPP experiment 7.webp
15Mar SLUPP experiment 6.webp





Conclusion:

  • SLUPP doesn't appear to be immediately soluble in straight oil, or not soluble at all in MCT it seems


Questions:
  • I'm looking for suggestions on what to add to this while it stays in the fridge. Although I'm not a fan of AI this is the response I got regarding whether SLUPP is soluble in oil: "Yes, SLU-PP-332 is soluble in oil. According to MedchemExpress.com, a clear solution can be prepared by dissolving it in corn oil, specifically at a concentration of at least 2.5 mg/mL, typically by first creating a DMSO stock solution (25 mg/mL) and mixing it with corn oil at a 1:9 ratio."
  • To avoid DMSO can I use EO?
  • @CladHQ did your source who sells it suspended in MCT oil mention that he adds anything other than just the MCT oil?

Thanks in advance for reading and for replying. I'm open to any advice or experience anyone has with trying to reconstitute SLUPP without water.


@LevButlerov @trenAMP @Nood @RawCutlery @liftedlivingwithlegacy @BigVelvetG @MarkNV @eazy_ @Neuro @US-pharmacies
@liftedlivingwithlegacy @LH5515 @justapotato @Allupfromhere @roguepineapple @fingers86 @Grumpy @Demon_throne @R.AP @rizzlekdizzle @Pigsy @Wookie @AusMade @Shakey @kcates @toddthelineman @ROIDDERS @2Thick @Ulter @ballin2504 @Mobster @stevesmi @kcates @Eddie Haskell
 
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Q: does the heat matter?
Great question. I thought it might so I didn't heat up the oil first.
If it is in the fridge too long while we figure this out I might have to add some BA to it.
 
I missed the mg amount in the vial. If corn oil needs 2,5 mg/ml, is that what you diluted it with the mct?
Thank you!!! Nice catch. I edited it to include that it's a 5mg vial of SLUPP sponsored by @biogenix

Ethyl oleate is a solvent, yes?
It is yes but the human safety profile and data is in check whereas with DMSO it's a no no (even transdermal DMSO is risky as it will fall into your subQ and bloodstream and bring every living organism on your skin in with it).

I can’t imagine that an oil solution would require refrigeration, but I can imagine warmth accelerating the absorption of the powder.
I have a 'gear and peptide fridge' that I keep at 5-6C and I just keep everything in there.

You're right about heat though, sometimes my DHB would crash or high concentrate T and all I'd have to do is microwave it for about 30 seconds and bam it was good to go.

This is fun! Hahaha
It is fun, I wonder if I should microwave the vial and heat up the oil. At the very least I'll take it out of the fridge for now.
 
I just reconstituted it with filtered C8 MCT oil this morning and I'm going to wait an hour for it to dissolve and then post results here. Haven't started running it yet no. It doesn't seem to be dissolving in MCT as the oil is just sitting on top so I'm thinking your source that sells it as a product in oil must add EO or some other compound for solubility. I'll know more in an hour or two. I'm trying to give them time to inter mingle without shaking the shit out of it LOL
Did you warm the oil up? I know oils are warmed to help dissolve compounds right? Depending on solvent additions more or less heat can be used. Usually 40°C - 50°C for most, and up to 60°C if need for really stubborn compounds but not past 60°C.

THe additions of both Benzol Alcohol and Benzol Benzoate help with dissolution.

Make a warm water bath to set vial in. Got a thermometer? Take the water to 50°C lets it warm and swirl away.
 
SLUPP Solubility with MCT Oil Experiment - Process and Results




Process:
  • 5mg vial of SLU-PP-332 sponsored by @biogenix
  • Draw and filter until a total of 2ml of MCT oil is obtained using a PES 0.22nm filter
  • Backload the 2ml of filtered MCT oil into a new syringe for reconstitution
  • Load vial of SLUPP with the 2ml of filtered MCT oil for reconstitution


View attachment 199186View attachment 199187View attachment 199188View attachment 199189View attachment 199190




Observations:


  • Upon loading with MCT oil the oil sat on top of the peptide puck as seen in pic
  • The oil was swirled in the vial every 5 minutes
  • After time t = 1 hour the oil was still seen sitting on top of the SLUPP peptide with no dispersion

View attachment 199191View attachment 199192




Conclusion:

  • SLUPP doesn't appear to be immediately soluble in straight oil, or not soluble at all in MCT it seems


Questions:
  • I'm looking for suggestions on what to add to this while it stays in the fridge. Although I'm not a fan of AI this is the response I got regarding whether SLUPP is soluble in oil: "Yes, SLU-PP-332 is soluble in oil. According to MedchemExpress.com, a clear solution can be prepared by dissolving it in corn oil, specifically at a concentration of at least 2.5 mg/mL, typically by first creating a DMSO stock solution (25 mg/mL) and mixing it with corn oil at a 1:9 ratio."
  • To avoid DMSO can I use EO?
  • @CladHQ did your source who sells it suspended in MCT oil mention that he adds anything other than just the MCT oil?

Thanks in advance for reading and for replying. I'm open to any advice or experience anyone has with trying to reconstitute SLUPP without water.


@LevButlerov @trenAMP @Nood @RawCutlery @liftedlivingwithlegacy @BigVelvetG @MarkNV @eazy_ @Neuro @US-pharmacies
@liftedlivingwithlegacy @LH5515 @justapotato @Allupfromhere @roguepineapple @fingers86 @Grumpy @Demon_throne @R.AP @rizzlekdizzle @Pigsy @Wookie @AusMade @Shakey @kcates @toddthelineman @ROIDDERS @2Thick @Ulter @ballin2504 @Mobster @stevesmi @kcates @Eddie Haskell
Very interesting
As everyone is saying maybe heat will work but will that affect the slu in the process
 
I have some here, injectable SLU-PP-332, was give before my sponsorship with UGL OZ, I haven't used yet. Will reconstitute and see how it goes and post pics.
 
Does the vial not have metal? Hope could you microwave it?
I decided against it and immersed it in pre-boiling water... pics to follow... got the oil close to 60C or so... still nothing!

I'm almost ready to put Windex in this f*cker LOL:ROFLMAO:
 
I have some here, injectable SLU-PP-332, was give before my sponsorship with UGL OZ, I haven't used yet. Will reconstitute and see how it goes and post pics.
Let me know what you use to reconstitute. BAC water comes out super clear but with it being hydrophobic it's likely not dispersed at all. The oil isn't working so far either it seems to need a solvent and I'm thinking EO and some BA stat.
 
As everyone is saying maybe heat will work but will that affect the slu in the process
It's a good point but momentary heat for dissolution shouldn't break it down. Jano did a test and left GH outside all day in the sun and it still came back fine.
 
SLUPP Solubility with 🔥**hot**🔥 MCT Oil Experiment - Process and Results



Process:
  • Room temp MCT oil was added at roughly 10am to which zero dissolution after 7 hours was observed
  • At roughly 6pm water was heated up to pre-boiling to bring oil up to about 55-60C upon immersion in water
  • Immersed in hot water for 20-30 mins
  • Turned off stove and let sit for another 20 mins
  • Swirled every 5 mins with tongs
  • Let sit for a half hour at room temp

15Mar SLUPP experiment 9.webp
15Mar SLUPP experiment 10.webp
15Mar SLUPP experiment 11.webp






Observations:


  • Oil stayed on top the entire time
  • Pic of one hour post hot oil below
15Mar SLUPP experiment 12.webp




Conclusion:

  • SLUPP doesn't appear to when MCT oil is added at high temperature


Questions:
  • I think I need a solvent, maybe EO with some BA. Any suggestions?

@LevButlerov @trenAMP @Nood @RawCutlery @liftedlivingwithlegacy @BigVelvetG @MarkNV @eazy_ @Neuro @US-pharmacies
@liftedlivingwithlegacy @LH5515 @justapotato @Allupfromhere @roguepineapple @fingers86 @Grumpy @Demon_throne @R.AP @rizzlekdizzle @Pigsy @Wookie @AusMade @Shakey @kcates @toddthelineman @ROIDDERS @2Thick @Ulter @ballin2504 @Mobster @stevesmi @kcates @Eddie Haskell
 
Last edited:
SLUPP Solubility with 🔥**hot**🔥 MCT Oil Experiment - Process and Results



Process:
  • Room temp MCT oil was added at roughly 10am to which zero dissolution after 7 hours was observed
  • At roughly 6pm water was heated up to pre-boiling to bring oil up to about 55-60C upon immersion in water
  • Immersed in hot water for 20-30 mins
  • Turned off stove and let sit for another 20 mins
  • Swirled every 5 mins with tongs
  • Let sit for a half hour at room temp

View attachment 199283View attachment 199286View attachment 199287





Observations:


  • Oil stayed on top the entire time



Conclusion:

  • SLUPP doesn't appear to when MCT oil is added at high temperature


Questions:
  • I think I need a solvent, maybe EO with some BA. Any suggestions?

@LevButlerov @trenAMP @Nood @RawCutlery @liftedlivingwithlegacy @BigVelvetG @MarkNV @eazy_ @Neuro @US-pharmacies
@liftedlivingwithlegacy @LH5515 @justapotato @Allupfromhere @roguepineapple @fingers86 @Grumpy @Demon_throne @R.AP @rizzlekdizzle @Pigsy @Wookie @AusMade @Shakey @kcates @toddthelineman @ROIDDERS @2Thick @Ulter @ballin2504 @Mobster @stevesmi @kcates @Eddie Haskell
Feckkk, on paper this experiment sounded pn point and i really was hoping it was going to be.. so the two stayed seperated in the end?
It really is fun! I'm going to get to the bottom of this! LOL :p
Not gonna lie its pretty exciting lol..
 
SLUPP Solubility with 🔥**hot**🔥 MCT Oil Experiment - Process and Results



Process:
  • Room temp MCT oil was added at roughly 10am to which zero dissolution after 7 hours was observed
  • At roughly 6pm water was heated up to pre-boiling to bring oil up to about 55-60C upon immersion in water
  • Immersed in hot water for 20-30 mins
  • Turned off stove and let sit for another 20 mins
  • Swirled every 5 mins with tongs
  • Let sit for a half hour at room temp

View attachment 199283View attachment 199286View attachment 199287





Observations:


  • Oil stayed on top the entire time



Conclusion:

  • SLUPP doesn't appear to when MCT oil is added at high temperature


Questions:
  • I think I need a solvent, maybe EO with some BA. Any suggestions?

@LevButlerov @trenAMP @Nood @RawCutlery @liftedlivingwithlegacy @BigVelvetG @MarkNV @eazy_ @Neuro @US-pharmacies
@liftedlivingwithlegacy @LH5515 @justapotato @Allupfromhere @roguepineapple @fingers86 @Grumpy @Demon_throne @R.AP @rizzlekdizzle @Pigsy @Wookie @AusMade @Shakey @kcates @toddthelineman @ROIDDERS @2Thick @Ulter @ballin2504 @Mobster @stevesmi @kcates @Eddie Haskell
I'm thinking you can test both EO and BA but adding BA would make it painful but at least bacteria would go down :D @HarleyGuy but this would be too complex for about 99% of EVO brothers to experiment they need to just oral it up :D
 
Feckkk, on paper this experiment sounded pn point and i really was hoping it was going to be.. so the two stayed seperated in the end?
Ya man. It's a conundrum. It's hydrophobic yet reconstitutes pleasurably to the naked eye with BAC water and with MCT oil it's making want to take a flamethrower to it or dump some sulfuric acid in there! :mad::ROFLMAO:

15Mar SLUPP experiment 12.webp
 
I'm thinking you can test both EO and BA but adding BA would make it painful but at least bacteria would go down :D @HarleyGuy but this would be too complex for about 99% of EVO brothers to experiment they need to just oral it up :D
That's about the final conclusion I'm getting at now, agreed.

What I'm wondering about is that @CladHQ sent me a link to a vendor who sells it suspended in MCT oil so now I'd like to know what solvent is in there as well (there clearly must be) because it obviously needs a lower viscosity carrier (kinda like BAC water haha) to dissolve.

I'll add some EO next.
 
That's about the final conclusion I'm getting at now, agreed.

What I'm wondering about is that @CladHQ sent me a link to a vendor who sells it suspended in MCT oil so now I'd like to know what solvent is in there as well (there clearly must be) because it obviously needs a lower viscosity carrier (kinda like BAC water haha) to dissolve.

I'll add some EO next.
Loving the reverse engineering!!
 
SLUPP Solubility with MCT Oil Experiment - Process and Results




Process:
  • 5mg vial of SLU-PP-332 sponsored by @biogenix
  • Draw and filter until a total of 2ml of MCT oil is obtained using a PES 0.22nm filter
  • Backload the 2ml of filtered MCT oil into a new syringe for reconstitution
  • Load vial of SLUPP with the 2ml of filtered MCT oil for reconstitution


View attachment 199186View attachment 199187View attachment 199188View attachment 199189View attachment 199190




Observations:


  • Upon loading with MCT oil the oil sat on top of the peptide puck as seen in pic
  • The oil was swirled in the vial every 5 minutes
  • After time t = 1 hour the oil was still seen sitting on top of the SLUPP peptide with no dispersion

View attachment 199191View attachment 199192




Conclusion:

  • SLUPP doesn't appear to be immediately soluble in straight oil, or not soluble at all in MCT it seems


Questions:
  • I'm looking for suggestions on what to add to this while it stays in the fridge. Although I'm not a fan of AI this is the response I got regarding whether SLUPP is soluble in oil: "Yes, SLU-PP-332 is soluble in oil. According to MedchemExpress.com, a clear solution can be prepared by dissolving it in corn oil, specifically at a concentration of at least 2.5 mg/mL, typically by first creating a DMSO stock solution (25 mg/mL) and mixing it with corn oil at a 1:9 ratio."
  • To avoid DMSO can I use EO?
  • @CladHQ did your source who sells it suspended in MCT oil mention that he adds anything other than just the MCT oil?

Thanks in advance for reading and for replying. I'm open to any advice or experience anyone has with trying to reconstitute SLUPP without water.


@LevButlerov @trenAMP @Nood @RawCutlery @liftedlivingwithlegacy @BigVelvetG @MarkNV @eazy_ @Neuro @US-pharmacies
@liftedlivingwithlegacy @LH5515 @justapotato @Allupfromhere @roguepineapple @fingers86 @Grumpy @Demon_throne @R.AP @rizzlekdizzle @Pigsy @Wookie @AusMade @Shakey @kcates @toddthelineman @ROIDDERS @2Thick @Ulter @ballin2504 @Mobster @stevesmi @kcates @Eddie Haskell
I think the oil suspension they have has EO in it or they are mixing BB/BA in it as well its hard to say especially with slu @HarleyGuy
 
I think the oil suspension they have has EO in it or they are mixing BB/BA in it as well its hard to say especially with slu @HarleyGuy
Agreed it clearly must have EO in it. I should have some by tomorrow or Tuesday.
Sorry man I can't let this one go LOL. :p

I'll stop tagging everyone sorry everyone :ROFLMAO: but do check in here to see the final result! I don't think anyone on the internet anywhere, including podcasts, has done this yet.
 
SLUPP Solubility with 🔥**hot**🔥 MCT Oil Experiment - Process and Results



Process:
  • Room temp MCT oil was added at roughly 10am to which zero dissolution after 7 hours was observed
  • At roughly 6pm water was heated up to pre-boiling to bring oil up to about 55-60C upon immersion in water
  • Immersed in hot water for 20-30 mins
  • Turned off stove and let sit for another 20 mins
  • Swirled every 5 mins with tongs
  • Let sit for a half hour at room temp

View attachment 199283View attachment 199286View attachment 199287





Observations:


  • Oil stayed on top the entire time
  • Pic of one hour post hot oil below
View attachment 199313



Conclusion:

  • SLUPP doesn't appear to when MCT oil is added at high temperature


Questions:
  • I think I need a solvent, maybe EO with some BA. Any suggestions?

@LevButlerov @trenAMP @Nood @RawCutlery @liftedlivingwithlegacy @BigVelvetG @MarkNV @eazy_ @Neuro @US-pharmacies
@liftedlivingwithlegacy @LH5515 @justapotato @Allupfromhere @roguepineapple @fingers86 @Grumpy @Demon_throne @R.AP @rizzlekdizzle @Pigsy @Wookie @AusMade @Shakey @kcates @toddthelineman @ROIDDERS @2Thick @Ulter @ballin2504 @Mobster @stevesmi @kcates @Eddie Haskell
Wow still not mixing
 
Thanks so much for hopping onto this research thread @AusMade I've added you to the original research post of EVO users for SLUPP.

This is some amazing feedback from both the low dosing camp of EVO brothers as well some anecdotal feedback for oral dosing and NOT in any type of pill form but instead a liquid mix.

Two questions
1. Do you know if it's carried in BAC water as it's liquid?
2. Do you swallow it or let it sit in the mouth a bit to get some sublingual absorption?
My source didnt tell me how its made, but its milkyish liquid dosed at 2mg/ml.

Ive been just squirting in my mouth and drinking, but ill try letting it sit under my lounge tomorrow onwards to see if any better effect.
 
Wow still not mixing
Ya it's been super interesting. Proof that SLUPP 'appears' to dissolve in BAC water and doesn't in oil despite 'requiring' oil, so clearly some form of solvent is needed not unlike high concentration gear like T400 or Primo200 etc.
 
My source didnt tell me how its made, but its milkyish liquid dosed at 2mg/ml.
This makes total sense. The oil sitting above the SLUPP puck has gotten slightly less clear and is a bit milky but the puck is being stubborn.

Would your source disclose what he uses by any chance?

I have 2ml in the 5mg vial so mine would be 2.5mg per ml.
 
Ya it's been super interesting. Proof that SLUPP 'appears' to dissolve in BAC water and doesn't in oil despite 'requiring' oil, so clearly some form of solvent is needed not unlike high concentration gear like T400 or Primo200 etc.
Very interesting i have a vial i might play around with
 
Very interesting i have a vial i might play around with
Haha let me do the wasting of peptides and use this thread as your guide or I'll feel bad. Unless you wanna experiment and have some solvent go for it! Don't use windex though :ROFLMAO:. Ammonia unzips your DNA!
 
This makes total sense. The oil sitting above the SLUPP puck has gotten slightly less clear and is a bit milky but the puck is being stubborn.

Would your source disclose what he uses by any chance?

I have 2ml in the 5mg vial so mine would be 2.5mg per ml.
Sorry mate, some people keep their secret herbs and spices recipes to themselves. I did ask tho
 
Sorry mate, some people keep their secret herbs and spices recipes to themselves. I did ask tho
Ya I totally respect that, but you don't shoot you don't score... thanks for asking maybe he'll help out. Either way I'm getting to the bottom of this LOL
 
Ya it's been super interesting. Proof that SLUPP 'appears' to dissolve in BAC water and doesn't in oil despite 'requiring' oil, so clearly some form of solvent is needed not unlike high concentration gear like T400 or Primo200 etc.

This makes total sense. The oil sitting above the SLUPP puck has gotten slightly less clear and is a bit milky but the puck is being stubborn.

Would your source disclose what he uses by any chance?

I have 2ml in the 5mg vial so mine would be 2.5mg per ml.
I think slu pp 332 will fall into the "orals" category in general here. To me it looks like oral dbol vs injectable dbol or oral winstrol vs injectable winstrol, yes in theory injecting winstrol or dbol gives you stronger absorption, but in reality its much easier to take it orally tbh :D @HarleyGuy while higher doses might be required, it's a lot less pinning and a less PIP in the end :D
 
I think slu pp 332 will fall into the "orals" category in general here. To me it looks like oral dbol vs injectable dbol or oral winstrol vs injectable winstrol, yes in theory injecting winstrol or dbol gives you stronger absorption, but in reality its much easier to take it orally tbh :D @HarleyGuy while higher doses might be required, it's a lot less pinning and a less PIP in the end :D
This is making more and more sense to me now especially after all this darn experimenting. I'll be doing sublingual moving forward.

Let's keep this research thread going for dosing and effects/side effects too.

Also a special mention to @Allupfromhere for writing this here, which all should read first before throwing in any mito peptide haphazardly: Mito Health Community Thread
 
SLUPP Solubility with 🔥**hot**🔥 MCT Oil Experiment - Process and Results



Process:
  • Room temp MCT oil was added at roughly 10am to which zero dissolution after 7 hours was observed
  • At roughly 6pm water was heated up to pre-boiling to bring oil up to about 55-60C upon immersion in water
  • Immersed in hot water for 20-30 mins
  • Turned off stove and let sit for another 20 mins
  • Swirled every 5 mins with tongs
  • Let sit for a half hour at room temp

View attachment 199283View attachment 199286View attachment 199287





Observations:


  • Oil stayed on top the entire time
  • Pic of one hour post hot oil below
View attachment 199313



Conclusion:

  • SLUPP doesn't appear to when MCT oil is added at high temperature


Questions:
  • I think I need a solvent, maybe EO with some BA. Any suggestions?

@LevButlerov @trenAMP @Nood @RawCutlery @liftedlivingwithlegacy @BigVelvetG @MarkNV @eazy_ @Neuro @US-pharmacies
@liftedlivingwithlegacy @LH5515 @justapotato @Allupfromhere @roguepineapple @fingers86 @Grumpy @Demon_throne @R.AP @rizzlekdizzle @Pigsy @Wookie @AusMade @Shakey @kcates @toddthelineman @ROIDDERS @2Thick @Ulter @ballin2504 @Mobster @stevesmi @kcates @Eddie Haskell

Great write-up — really nice that you make these notes and describe everything like this. SLUPP needs a stabilizer — in this case, the experiment you did didn’t work because of the wrong active substance. What that means is you used the lyophilized form of SLUPP — already processed, containing mannitol, a stabilizing substance for the liquid used during lyophilization (water) — and it doesn’t dissolve in oil :) — and that’s the problem :)

Summary: you need the pure active SLUPP substance :) Then BA, BB for stabilization will work fine.

@trenAMP @Nood @RawCutlery @liftedlivingwithlegacy
@BigVelvetG @MarkNV @eazy_ @Neuro @Noah Wixx
 
SLUPP Solubility with MCT Oil Experiment - Process and Results




Process:
  • 5mg vial of SLU-PP-332 sponsored by @biogenix
  • Draw and filter until a total of 2ml of MCT oil is obtained using a PES 0.22nm filter
  • Backload the 2ml of filtered MCT oil into a new syringe for reconstitution
  • Load vial of SLUPP with the 2ml of filtered MCT oil for reconstitution


View attachment 199186View attachment 199187View attachment 199188View attachment 199189View attachment 199190




Observations:


  • Upon loading with MCT oil the oil sat on top of the peptide puck as seen in pic
  • The oil was swirled in the vial every 5 minutes
  • After time t = 1 hour the oil was still seen sitting on top of the SLUPP peptide with no dispersion

View attachment 199191View attachment 199192




Conclusion:

  • SLUPP doesn't appear to be immediately soluble in straight oil, or not soluble at all in MCT it seems


Questions:
  • I'm looking for suggestions on what to add to this while it stays in the fridge. Although I'm not a fan of AI this is the response I got regarding whether SLUPP is soluble in oil: "Yes, SLU-PP-332 is soluble in oil. According to MedchemExpress.com, a clear solution can be prepared by dissolving it in corn oil, specifically at a concentration of at least 2.5 mg/mL, typically by first creating a DMSO stock solution (25 mg/mL) and mixing it with corn oil at a 1:9 ratio."
  • To avoid DMSO can I use EO?
  • @CladHQ did your source who sells it suspended in MCT oil mention that he adds anything other than just the MCT oil?

Thanks in advance for reading and for replying. I'm open to any advice or experience anyone has with trying to reconstitute SLUPP without water.


@LevButlerov @trenAMP @Nood @RawCutlery @liftedlivingwithlegacy @BigVelvetG @MarkNV @eazy_ @Neuro @US-pharmacies
@liftedlivingwithlegacy @LH5515 @justapotato @Allupfromhere @roguepineapple @fingers86 @Grumpy @Demon_throne @R.AP @rizzlekdizzle @Pigsy @Wookie @AusMade @Shakey @kcates @toddthelineman @ROIDDERS @2Thick @Ulter @ballin2504 @Mobster @stevesmi @kcates @Eddie Haskell
Another terrific post by Harley. Keep up the good work, champ. Lots of good knowledge in this.
 
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