@Bluebone looking jacked bro!Didn’t get around to posting check-in photos from yesterday
@Bluebone looking jacked bro!Didn’t get around to posting check-in photos from yesterday
do you have the actual bloods with range on it? just curious to see pleaseHey guys.
My e2 isn't currently where I want it. Just got results back from a test few days ago.
Have been doing more regular blood tests just for e2 to monitor it after coming off a stack including boldenone cypionate (just cheaper to do more frequently than getting my usual comprehensive panel).
Want it to be higher - at least 110pmol/L (i think American units are typically pg/ml - so take my pmol/L and divide by ~3.67 to get to what you're more familiar with.)
Bloods show my e2 is currently <100pmol/L. Once it's below this the basic tests can't give you any detail on what the exact figure is. I'd have to get high sensitivity e2 LCMS to be able to get this figure - and that take 2 weeks to get results.
So for now I'm going to drop primo altogether for 2 weeks and bump test by 100mg/week (more aromatase substrate), and bump mast a little bit for it's SERM like affects in case i go too far in the other direction on e2. I'll retake bloods and when my e2 is where I want it I'll slowly re-introduce primo.
Just don't want to risk any tears (or sub-optimal igf-1 conversion from GH) that could slow down progress. So playing it cautious with the drop of primo and ramp of test.
So for the next couple of weeks weekly dosages will look like the following:
400mg test; 150mg NPP, 150mg Mast E
lower body is legit man30th Nov (Saturday) Training Log
Lower Body Session
A1 – Front Squats: 95kg/8, 100/8, 110/6, 110/6
- All weight in kg
- Sets recorded do not include warmup sets
A2 – Seated Leg curl: 57/12, 57/12, 57/12, 57/12
B1 – Rear Foot Elevated Split Squat (25kg db each hand, a set is 10 reps each leg)
25/10, 25/10, 25/10
B2 – Romanian Deadlift: 100/10, 100/10, 100/10
C1 – Leg Extension: 45/14, 45/12, 45/12
C2 – Standing Cable Crunch: 41/12, 45/12, 45/12, 45/12
do you have the actual bloods with range on it? just curious to see please![]()
Hey mate - as per my post (post before the lab screenshot) basic e2 won’t give detail below 100pmol/L. They consider the basic test inaccurate below this (though some states in Australia will report down to 60pmol/L, mine doesn’t)bloods show <100 but they dont give details? @Bluebone
I only asked is because <100 could mean 99 or could mean 10 right, you could have crashed E2 that was my concern broHey mate - as per my post (post before the lab screenshot) basic e2 won’t give detail below 100pmol/L. They consider the basic test inaccurate below this (though some states in Australia will report down to 60pmol/L, mine doesn’t)
To get exact figure I have to order high sensitivity e2 lcms, which is more expensive and has a 2 week turnaround time. It’s not so much the money, it’s the turnaround time that’s the issue. That’s why I prefer to keep e2 above 100 (so it’s detectable in basic test) and preferably around 150pmol/L because I feel best there![]()
I’m with you bro.I only asked is because <100 could mean 99 or could mean 10 right, you could have crashed E2 that was my concern bro@Bluebone
interesting you get injuries with low e2, how bad was the injury and what was the estrogen level? @BlueboneI’m with you bro.
That’s why I’m dropping the primo for 2 weeks and re-testing. I’ll add back in slowly when I’m back at e2 I want.
I’m prone to injuries with low e2 so I’m not taking any chances![]()
Adductor tear. ~30pmol/L. So very low e2. Very annoying injuryinteresting you get injuries with low e2, how bad was the injury and what was the estrogen level? @Bluebone
what was your fat intake on the diet during this? do you recall specifically omega 3 intake broAdductor tear. ~30pmol/L. So very low e2. Very annoying injury
My fat intake is always significant. I don’t really try to restrict fats. Along time ago I used to count macros and optimise ratios, since being a dad my priorities have changed. So my diet is not optimised beyond trying to eat whole, good foods, limit processed junk (anlthough that still happens) etc. but I don’t eat lean cuts (eg happily eat scotch fillet, porterhouse with fat on, heaps of whole fat yoghurt ) etc. I eat plenty of fat including when I had this injury (including plenty of seafood, salmon / omega 3 rich sources [as well as cod liver oil supplementation])what was your fat intake on the diet during this? do you recall specifically omega 3 intake bro
fair enough, the reason I asked, multiple guys I train had issues with low fat intake and injuries, as soon as we modified omega 3 fat intake (not saturated) up, I noticed a huge decrease in injuries broMy fat intake is always significant. I don’t really try to restrict fats. Along time ago I used to count macros and optimise ratios, since being a dad my priorities have changed. So my diet is not optimised beyond trying to eat whole, good foods, limit processed junk (anlthough that still happens) etc. but I don’t eat lean cuts (eg happily eat scotch fillet, porterhouse with fat on, heaps of whole fat yoghurt ) etc. I eat plenty of fat including when I had this injury (including plenty of seafood, salmon / omega 3 rich sources [as well as cod liver oil supplementation])
PS I know I could get better results if I optimised diet for bodybuilding purposes but I’m just not interested at the moment![]()
strong training day pull downs all 10s? how about a 12-15 pull down next time broDelayed posting of yesterday's workout. Just realised i completely forgot to do cable lateral raises. d'oh
1st December (Sunday) Upper Body:
Notes:
A1 - 60deg Seated Db Press: 40/8, 40/8, 40/8, 40/8
- Warmups not included in the below
- Other than warmups for the exercises below – usually do a few activation exercises at start of workout, Lock shoulder 3, Y-raises, lightweight tricep pushdowns, etc.
- Tricep tendonitis was being a b*tch today after finishing dumbbell press and moving to close grip bench. Had to significantly regress weight on close grip bench to 80kg
- All weights in kg
A2 – Reverse Grip Pulldown: 85/10, 85/10, 85/10, 85/10
B1 – Close Grip Bench Press (significant tricep tendonitis so had to drop weight a lot)
80/10, 80/10, 80/10
B2: One Arm Db Row (flat bench): 37.5/12, 37.5/12, 37.5/12
D – BB Wide grip rear delt row immediately followed by Face Pulls :
35/15 -> 41/15; 40/15 -> 45/15; 40/15 -> 45/12
E -Db ext. rotation on knee: 5/15, 6/15, 6/12
That's how I'd wanna rollstrong training day pull downs all 10s? how about a 12-15 pull down next time bro
@Bluebone this is solid work right here!Delayed posting of yesterday's workout. Just realised i completely forgot to do cable lateral raises. d'oh
1st December (Sunday) Upper Body:
Notes:
A1 - 60deg Seated Db Press: 40/8, 40/8, 40/8, 40/8
- Warmups not included in the below
- Other than warmups for the exercises below – usually do a few activation exercises at start of workout, Lock shoulder 3, Y-raises, lightweight tricep pushdowns, etc.
- Tricep tendonitis was being a b*tch today after finishing dumbbell press and moving to close grip bench. Had to significantly regress weight on close grip bench to 80kg
- All weights in kg
A2 – Reverse Grip Pulldown: 85/10, 85/10, 85/10, 85/10
B1 – Close Grip Bench Press (significant tricep tendonitis so had to drop weight a lot)
80/10, 80/10, 80/10
B2: One Arm Db Row (flat bench): 37.5/12, 37.5/12, 37.5/12
D – BB Wide grip rear delt row immediately followed by Face Pulls :
35/15 -> 41/15; 40/15 -> 45/15; 40/15 -> 45/12
E -Db ext. rotation on knee: 5/15, 6/15, 6/12
Being sick and training usually ends badly but very nice to see you so dedicated.Yesterday's gym session. Probably shouldn't have gone - picked up something from our kids and deadlifting with greenshit coming out of my nose isn't a good look. Made sure to disinfect everything I used and got out of there pronto. Took today off gym though (usually upper body session) as still sick.
Wednesday 4th Dec Training Log (Lower Body)
Notes-
A – Adductor & Abductor Machine Superset – 23kg/20ea, 29/20ea, 29/20ea
- All weights in kg
- Warmup sets not recorded
B – Deadlift -150kg/5, 130/8, 130/8, 130/8
C1 – Incline back extension (snatch grip barbell)
C1 – Lying Cable Garhammer Raise – 9/14, 9/15, 14/12
C2 – Glute Ham Raise – BW/8, BW/8, BW/8
@Bluebone maintaining gym hygiene is important....always take care of it.......Yesterday's gym session. Probably shouldn't have gone - picked up something from our kids and deadlifting with greenshit coming out of my nose isn't a good look. Made sure to disinfect everything I used and got out of there pronto. Took today off gym though (usually upper body session) as still sick.
Wednesday 4th Dec Training Log (Lower Body)
Notes-
A – Adductor & Abductor Machine Superset – 23kg/20ea, 29/20ea, 29/20ea
- All weights in kg
- Warmup sets not recorded
B – Deadlift -150kg/5, 130/8, 130/8, 130/8
C1 – Incline back extension (snatch grip barbell)
C1 – Lying Cable Garhammer Raise – 9/14, 9/15, 14/12
C2 – Glute Ham Raise – BW/8, BW/8, BW/8
NiceDelayed posting of yesterday's workout. Just realised i completely forgot to do cable lateral raises. d'oh
1st December (Sunday) Upper Body:
Notes:
A1 - 60deg Seated Db Press: 40/8, 40/8, 40/8, 40/8
- Warmups not included in the below
- Other than warmups for the exercises below – usually do a few activation exercises at start of workout, Lock shoulder 3, Y-raises, lightweight tricep pushdowns, etc.
- Tricep tendonitis was being a b*tch today after finishing dumbbell press and moving to close grip bench. Had to significantly regress weight on close grip bench to 80kg
- All weights in kg
A2 – Reverse Grip Pulldown: 85/10, 85/10, 85/10, 85/10
B1 – Close Grip Bench Press (significant tricep tendonitis so had to drop weight a lot)
80/10, 80/10, 80/10
B2: One Arm Db Row (flat bench): 37.5/12, 37.5/12, 37.5/12
D – BB Wide grip rear delt row immediately followed by Face Pulls :
35/15 -> 41/15; 40/15 -> 45/15; 40/15 -> 45/12
E -Db ext. rotation on knee: 5/15, 6/15, 6/12
Glad to have you back brotherHey guys.
No posts for a bit as have had a dog of a strain of covid. Last time i had covid just felt like a common cold, this one was an absolute dog that was real chesty. Wife got hit worse. Kids brought it home from daycare, at least it was way better for them which was good.
Hit the gym today for the first time in a week, work capacity was down (airways still pretty sludgy), but have tested negative for the last few days so not contagious.
Workout below. Should rotate to a new workout plan in the next few days.
Wednesday 11th Dec Training Log (Lower Body)
Notes-
A – Adductor & Abductor Machine Superset
- All weights in kg
- Warmup sets not recorded
- Adductor: 30/15, 35/12
- Abductor: 40/15, 45/12
B – Deadlift: 145kg/5, 130/8, 130/8, 130/8
C1 – Incline back extension (snatch grip barbell): 40/10, 40/10
C1 – Lying Cable Garhammer Raise – 9/12, 14/12, 16.8/18
C2 – Glute Ham Raise – BW/12, BW/10, BW/10
Training is how I like it back and strong broHey guys.
No posts for a bit as have had a dog of a strain of covid. Last time i had covid just felt like a common cold, this one was an absolute dog that was real chesty. Wife got hit worse. Kids brought it home from daycare, at least it was way better for them which was good.
Hit the gym today for the first time in a week, work capacity was down (airways still pretty sludgy), but have tested negative for the last few days so not contagious.
Workout below. Should rotate to a new workout plan in the next few days.
Wednesday 11th Dec Training Log (Lower Body)
Notes-
A – Adductor & Abductor Machine Superset
- All weights in kg
- Warmup sets not recorded
- Adductor: 30/15, 35/12
- Abductor: 40/15, 45/12
B – Deadlift: 145kg/5, 130/8, 130/8, 130/8
C1 – Incline back extension (snatch grip barbell): 40/10, 40/10
C1 – Lying Cable Garhammer Raise – 9/12, 14/12, 16.8/18
C2 – Glute Ham Raise – BW/12, BW/10, BW/10
Hope it aids your recovery brother. TA1 is truly a remarkable peptide.Despite feeling like arse still have some conditionthanks to @Core Pharma & @Raptor Labs
@Core Pharma has also hooked me up with some thymosin alpha 1 to help the old Covid recovery. Reading up on it - TA-1 sounds awesome so we’ll see how it goes![]()
Absolute dog of a session today. Felt like crap. Today as way worse than yesterday, strength felt down. Work capacity even worse than yesterday. Just got to push on through and this'll clear up eventually. It's only been a little over a week since i first got sick so early days. See how i go with the weekend workouts.
12th December (Thursday) Upper Body:
Notes:
A1 - 60deg Seated Db Press: 42.5kg dumbells/7, 42.5/6, 40/8, 40/6
- Warmups not included in the below
- Other than warmups for the exercises below – usually do a few activation exercises at start of workout, Lock shoulder 3, Y-raises, lightweight tricep pushdowns, etc.
- Swapped out secondary bench for standing cable chest press, ws just feeling like absolute trash after seated press and lat pulldowns. Dropped some sets in accessory work
- All weights in kg
A2 – Reverse Grip Pulldown: 85/12, 85/10, 75/13, 80/11
B1 – Standing cable chest press : 27.2/15, 31.8/12, 31.8/12
B2: One Arm Db Row (flat bench): 37.5/12, 35/12, 35/12
C1 – Cable Laterals: 11.3/9ea, 9/10
C2 – BB Wide grip rear delt row immediately followed by Face Pulls :
40/15 -> 43.3/12; 40/15 -> 41/10
D - Db ext. rotation on knee: 6/10ea, 6/10ea
@Bluebone it takes time to recover fully broDespite feeling like arse still have some conditionthanks to @Core Pharma & @Raptor Labs
@Core Pharma has also hooked me up with some thymosin alpha 1 to help the old Covid recovery. Reading up on it - TA-1 sounds awesome so we’ll see how it goes![]()
missing a few exercises no issues you're pumping hard here alreadyDefinitely on the mend. Felt decently better today. TA1 may be helping too.
Had to leave gym early to pick up kids so missed last 2 exercises - leg extensions and standing cable crunch.
14th Dec Training Log
Lower Body Session
A1 – Front Squats: 80kg/8, 100/6, 100/6, 115/5
- All weight in kg
- Sets recorded do not include warmup sets
A2 – Seated Leg curl: 57/10, 57/10, 57/10, 57/10
B1 – Rear Foot Elevated Split Squat (27.5kg db each hand, a set is 8 reps each leg)
27.5/8ea, 27.5/8ea, 27.5/8ea
B2 – Romanian Deadlift: 100/10, 100/10, 100/10
Would..And the old photo checkin from todays session
Cheers to @Core Pharma & @Raptor Labs for fueling the rig
You’ve got a helluva transformation mate looking at those before and aftersWould..
You’ve got a helluva transformation mate looking at those before and after![]()
I’ll get the lube ready
Thursday 15th Dec Training Log (Upper Body)
Notes:
A1 – Barbell bench Press – 120kg/6, 120/6, 120/6, 120/6
- All weights in kg
- Warmup & activation sets not recorded
- Went easy on a lot of exercises – kept at least a couple RIR especially on bench
A2 – Arched Back (thoracic) Pulldown – Mid-sized MAG/Neutral Bar:
79/10, 79/10, 79/10, 79/10
B1 – 15deg Incline Db Bench Press
45/8, 45/8, 45/7
B2 – Single Arm Cable Row: 65/12ea, 65/12ea, 65/12ea
C - Seated Behind The Neck Press (I keep these light and move slowly through eccentric):
35/10, 35/10, 35/10
D1 - Incline Db Biceps Curl: 15/12, 15/12, 15/12
D2 - Powell Raise: 6/10, 6/10, 6/10
amazing picture, you look shredded and leanAnd the old photo checkin from todays session
Cheers to @Core Pharma & @Raptor Labs for fueling the rig
RippedAnd the old photo checkin from todays session
Cheers to @Core Pharma & @Raptor Labs for fueling the rig
Yep - my first thought tooamazing picture, you look shredded and leanWOW the training is paying off too
Looking sexy babeAnd the old photo checkin from todays session
Cheers to @Core Pharma & @Raptor Labs for fueling the rig
Looking forward to seeing the resultsgot bloods drawn today too.
quiet a large panel. forgot to include LCMS testosterone to separate out nandrolone and testosterone but oh well, next time in around 4 weeks.
Got IGF-1 so we can see how @Raptor Labs GH is hitting me. But judging by my results, fat fingers and their janoshik testing I'd say itll be pretty good. Timely testing because I just ran out of their GH too, so was keen to get the bloods done before I'd finished it all.
Other hormones I've also got down are e2, progesterone, prolactin, DHT (which usually also comes with LCMS e2) off the top of my head.
Haven't had hb1ac for awhile so also keen to see how that's looking to provide a proxy for average blood glucose over the last few months.
(+all the usual extras in bloods: liver, kidney health, lipids, haematology etc)
Will report back as i get results, but LCMS DHT+e2 will prob be a week or 2
@Bluebone looking incredible bro!And the old photo checkin from todays session
Cheers to @Core Pharma & @Raptor Labs for fueling the rig
Wednesday 18th Dec Training Log (Lower Body)
Notes-
A – Adductor & Abductor Machine Superset
- All weights in kg
- Warmup sets not recorded
– Adductor (1sec pause at end ranges): 37.5/12, 35/10
Abductor: 37.5/18, 35/15
B – Deadlift: 150kg/5, 135/8, 135/8, 135/8
C1 – Incline back extension (snatch grip barbell): 30/12, 30/12, 40/10
C1 – Lying Cable Garhammer Raise – 9/12, 14/12, 14/12
C2 – Glute Ham Raise – BW/12, BW/10
@Bluebone want to see how your e2 is myself actuallygot bloods drawn today too.
quiet a large panel. forgot to include LCMS testosterone to separate out nandrolone and testosterone but oh well, next time in around 4 weeks.
Got IGF-1 so we can see how @Raptor Labs GH is hitting me. But judging by my results, fat fingers and their janoshik testing I'd say itll be pretty good. Timely testing because I just ran out of their GH too, so was keen to get the bloods done before I'd finished it all.
Other hormones I've also got down are e2, progesterone, prolactin, DHT (which usually also comes with LCMS e2) off the top of my head.
Haven't had hb1ac for awhile so also keen to see how that's looking to provide a proxy for average blood glucose over the last few months.
(+all the usual extras in bloods: liver, kidney health, lipids, haematology etc)
Will report back as i get results, but LCMS DHT+e2 will prob be a week or 2
E2 results are back.@Bluebone want to see how your e2 is myself actually
checked training, your deads you getting stronger?
242 estrogen is high imo @AE1079 see hes upE2 results are back.
It has rebounded extremely quickly.
Dropped primo and upped test about 2 weeks ago from memory. Started getting the old nipple pain about 2 days ago so was expecting e2 to be up but was kind of surprised by where it rebounded to.
Adding primo back in now
(Regarding deadlifts - I have a back injury so by all rights I should be lifting more, but just being very slow and conservative with raising weights and really want to be triple sure the tissue tolerance has been rebuilt before upping weights)
your free test is at crazy levelnandrolone is interfere with testosterone results as expected. Again forgot to order testosterone LC-MS to differentiate, I’ll get it next time.
For the last 2 weeks I’ve been running 400 test e, 200 NPP and 150 Mast E to bump e2 up.
Before that I was running 300 T, 150 NPP, 100 mast e and 150 Primo E
Just added the primo back in as of today and I’ll drop my test back to 300 or so after seeing my recent e2 (above)
Low SHBG is consistent with this androgen load for me especially running DHT derivatives (and especially Anavar PWO)
Be good to see the E2 come down, but it’s sitting pretty darn good considering where the test numbers are at and no AI!
That’s why im bringing it down via primo (restarted this morning as soon as I got results). My sweet spot is between 110 and 160242 estrogen is high imo @AE1079 see hes up
You guys do realise these test numbers are skewed by nandrolone rightBe good to see the E2 come down, but it’s sitting pretty darn good considering where the test numbers are at and no AI!
Yeaaahhhh boiiiii - primo is working for you here !That’s why im bringing it down via primo (restarted this morning as soon as I got results). My sweet spot is between 110 and 160
I would say it would skew Estrogen not test - nandrolones are e-strains so in most assays it will come up as E2.You guys do realise these test numbers are skewed by nandrolone right
It’s not working because I haven’t been on it for 2 and half weeks bro. Context is importantYeaaahhhh boiiiii - primo is working for you here !
Agree Tren shows up as e2 on non LC-MS test. Structure is a whole lot more similar to e2 than nandrolone is.I would say it would skew Estrogen not test - nandrolones are e-strains so in most assays it will come up as E2.
I thought I read it was working for you I’ll read this through againIt’s not working because I haven’t been on it for 2 and half weeks bro. Context is important![]()
So wait Primo has worked for you in terms of E2 management? I’m a little confusedAgree Tren shows up as e2 on non LC-MS test. Structure is a whole lot more similar to e2 than nandrolone is.
I’d argue nandrolone is way more influential on a non-sensitive testosterone test than it is on e2. But hey it’s the internet I don’t really care![]()
haha big picture primo is absolutely working for e2 control my broSo wait Primo has worked for you in terms of E2 management? I’m a little confused
No I’m glad it’s working because I believe in primo strongly and it’s use as a potential to show good AI properties..haha big picture primo is absolutely working for e2 control my bro
I started 5 weeks ago at 300 t 150 Primo
Got a standard e2 test 2 - 3 weeks in because I always have to be careful of my e2 on eq and primo. My e2 was <100pmol/L. I like to keep it at least above 100 because I feel better and it’s fucked waiting for a lcms e2 test to see if you’re truly at 30pmol/L (basically crashed) or at 99 (just under the test resolution)
So I ditched primo, upped test by 100mg, (to get my e2 back up to around 110 to 160ish) and after 2.5 weeks these are the bloods you see. E2 has come ripping back fast without primo. I jumped back on primo today
Sorry bro I think I misinterpreted what you were sayingI thought you were being sarcastic like “yeah primo is REALLY working when you’re e2 is over 200”
![]()
Mate I think the case is closed there. Primo is a definite AI that provides anabolism to boot. It’s effects probably vary person to person but seems a pretty fucking effective AI in mostNo I’m glad it’s working because I believe in primo strongly and it’s use as a potential to show good AI properties..
Mate I think the case is closed there. Primo is a definite AI that provides anabolism to boot. It’s effects probably vary person to person but seems a pretty fucking effective AI in most
*edit: I should probably say it’s one of primo’s metabolites that acts as the AI rather than primo in its raw form
Atamestane? interesting, any studies on it? want to do some reading @AE1079That’s right bro, I have preaching that the metabolites of primo are the ones with the AI Properties called atamestane.. this is the new metabolite
There was a pretty good podcast with Todd Lee and Kurt Havens on this where relevant papers were mentioned. The name is similar to exemestane (aromasin) but can’t remember if the exact spelling was as aboveAtamestane? interesting, any studies on it? want to do some reading @AE1079
I'd like to see actual studies on it, would be nice to see, dont doubt it but have concerns about the actual metaboliteThere was a pretty good podcast with Todd Lee and Kurt Havens on this where relevant papers were mentioned. The name is similar to exemestane (aromasin) but can’t remember if the exact spelling was as above
Hb1ac results and fasted blood glucose
Even though my fasted blood glucose is looking pretty good, I like hb1ac better because it gives you longer term average of where your blood glucose is at. Charles Poliquin always loved this as a metric in people he was training.
So even though my fasted blood glucose looks decent at 4.7, that’s Is impacted by the amount of time I was fasting while waiting for bloods (took forever). So I refer back to my hb1ac result of 5.5 % / 6.2 average (which reflects non-fasted and fasted states as it’s an average over months) I’d like my result to be better than this. But it reflects the less cardio I’ve been doing over the last 2 months, and also eating a bit shit. So would look to improve for sure
waiting on more resultsI’ve got a bunch of results but just posting them as I get time
Have a look on pubmed, there’s heaps, I have done a deep dive on it already quite similar to aromasin being somewhat of a suicide AI - irreversibly binding. It doesn’t inhibit cytochrome p450 enzyme in the liver, so people with high p450 will still aromatise I would suggest hence some people don’t respond - I will nail this down to test being two high and primo not high enough to counteract E2 from binding to both EBR2 and EAR2 and It will stop the e2 negative feedback loop, so E1 shouldn’t be in play here converting to E2, which potentially could be used along side Nolva as Nolva still encouraged E1>E2 conversion.Atamestane? interesting, any studies on it? want to do some reading @AE1079
Oh I'm aware of Atamestane but this is an old ai but I'm not aware of how it ties to primobolanHave a look on pubmed, there’s heaps, I have done a deep dive on it already quite similar to aromasin being somewhat of a suicide AI - irreversibly binding. It doesn’t inhibit cytochrome p450 enzyme in the liver, so people with high p450 will still aromatise I would suggest hence some people don’t respond - I will nail this down to test being two high and primo not high enough to counteract E2 from binding to both EBR2 and EAR2 and It will stop the e2 negative feedback loop, so E1 shouldn’t be in play here converting to E2, which potentially could be used along side Nolva as Nolva still encouraged E1>E2 conversion.
Its the metabolite after primo has been broken down - of course its literature they aren’t going to sayOh I'm aware of Atamestane but this is an old ai but I'm not aware of how it ties to primobolan
this is the only decent study on it
https://pubmed.ncbi.nlm.nih.gov/1722797/
but no real ties to primo @AE1079
Of course the studies not clear on it I agreeIts the metabolite after primo has been broken down - of course its literature they aren’t going to say
“this is a metobolite of the popular steroids primobolan” - watch this space brother all will come to surface soon
I encourage you to have an open mind with these things - this field is ever evolving. We don’t have slot of data on these things and people rely on us to give them the data and findings, which I spend a lot of time doing research, learning and own anecdote. We are seeing people confirm E2 is decreasing due to primo and EQ, just like we see people have no affect at all (which I described above around cytochrome P450 enzyme). Keep on moving with the times, my views on things changes as well. It’s 2024 and not 2000 and it’s important that we stay up to date with literature and anecdotes. Science doesn’t always paint the right awnser and can be an Enigma to how things work. Which is the beauty of this spaceOh I'm aware of Atamestane but this is an old ai but I'm not aware of how it ties to primobolan
this is the only decent study on it
https://pubmed.ncbi.nlm.nih.gov/1722797/
but no real ties to primo @AE1079
I am very open minded, interested to see more evidence of primobolan and Atamestane not just from a debate point but a learning point for me as well, just not seeing it when I look @AE1079I encourage you to have an open mind with these things - this field is ever evolving. We don’t have slot of data on these things and people rely on us to give them the data and findings, which I spend a lot of time doing research, learning and own anecdote. We are seeing people confirm E2 is decreasing due to primo and EQ, just like we see people have no affect at all (which I described above around cytochrome P450 enzyme). Keep on moving with the times, my views on things changes as well. It’s 2024 and not 2000 and it’s important that we stay up to date with literature and anecdotes. Science doesn’t always paint the right awnser and can be an Enigma to how things work. Which is the beauty of this space
Well you have seen yourself in some users that E2 does at some point lowers with primo use - and I believe these are individuals with lower body fat and lower P450 to facilitate its effects, science is great and it provides a back bone to points for sure, but sometimes we can’t explain things from that point view as what we do in bodybuilding is not studied and won’t ever be funded or studied, we can take it with a pinch of salt, but I think it’s important to have a curious outlook as the space keeps developingI am very open minded, interested to see more evidence of primobolan and Atamestane not just from a debate point but a learning point for me as well, just not seeing it when I look @AE1079![]()
I'm trying to look for the actual chemical structure was reviewing it, not seeing it yet primobolan vs Atamestane I mean @AE1079Well you have seen yourself in some users that E2 does at some point lowers with primo use - and I believe these are individuals with lower body fat and lower P450 to facilitate its effects, science is great and it provides a back bone to points for sure, but sometimes we can’t explain things from that point view as what we do in bodybuilding is not studied and won’t ever be funded or studied, we can take it with a pinch of salt, but I think it’s important to have a curious outlook as the space keeps developing
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