Methylene Blue

[PrinceDaddy]

What is the TLDR on this supplement that seems to be in the news?

From Amazon

• PHARMACEUTICAL GRADE METHYLENE BLUE: Methylene Blue for clinical applications is the purest grade available & helps boost the energy production capabilities of mitochondria and may also protect against neurodegenerative disorders and memory loss
• MEMORY DEFENSE: Harness the power of antioxidants in our top-tier pharmaceutical grade methylene blue to combat cellular aging and support cognitive health
• EXACT CONCENTRATION AND ASSURED QUALITY: Boasting 99.9% purity, each of blue methylene drops delivers a precise 0.5mg dose, ensuring consistent strength for accurate application in therapeutic settings
• HIGHEST QUALITY: Trust in the exceptional purity and strength of our methylene blue usp consumption, rigorously tested and free from formaldehyde, adhering to US Pharmacopeia standards
• SECURE & CONVENIENT PACKAGING: Our methylene blue is packaged in glass bottles designed for easy dispensing. This packaging choice helps maintain the compound's potency, which can be compromised when stored in plastic containers

Chat-GPT
Methylene blue has several potential health benefits, though its use in medicine requires caution, as it can have side effects if not administered correctly. Here's a more detailed look at its health-related uses:

1.​

• What it is: Methemoglobinemia is a condition where hemoglobin, the molecule that carries oxygen in the blood, becomes oxidized and unable to effectively release oxygen to tissues.
• How methylene blue helps: Methylene blue works as a reducing agent, converting methemoglobin back to its normal form (hemoglobin), thus improving the oxygen-carrying capacity of the blood. It is commonly used in emergencies to treat this condition.
• Administration: It is typically administered intravenously in hospitals under medical supervision.

2.​

• Cognitive Function and Alzheimer's Disease: Research has been investigating methylene blue’s role in protecting neurons and improving brain function. Some studies suggest that it might help in diseases like Alzheimer’s by reducing oxidative stress, which can damage brain cells.
• Mitochondrial Health: Methylene blue has been found to support mitochondrial function. Since mitochondria are the powerhouses of cells, improving their function may help protect against cognitive decline and age-related diseases.
• Memory Enhancement: Some studies suggest that at low doses, methylene blue might improve memory and cognitive function, potentially offering benefits for those with cognitive impairment, though these effects are still being studied.

3.​

• Methylene blue has antioxidant effects, helping to neutralize free radicals and reduce oxidative stress in the body. This property may contribute to its potential neuroprotective effects and general health benefits, especially for conditions associated with oxidative damage.

4.​

• Methylene blue has been used historically to treat infections due to its antimicrobial properties. It can be effective against some bacteria and fungi, although it is not commonly used as a primary treatment today.
• It has also been used to treat urinary tract infections and as a topical antiseptic in certain cases.

5.​

• Methylene blue has been used in combination with other drugs to treat UTIs. It works by acting as a mild antiseptic, though more effective and targeted treatments are generally preferred for UTI management.

6.​

• Some preliminary studies have explored the use of methylene blue in cancer therapy. It has been shown to induce apoptosis (programmed cell death) in some cancer cells, and its ability to enhance mitochondrial function might also make it useful in preventing cancer cell survival. However, this is still an emerging area of research and should not be considered a standard cancer treatment.

7.​

• Some studies suggest that methylene blue may have an impact on mood and energy levels due to its role in mitochondrial function and its effects on brain chemistry. However, these effects are not well established and more research is needed to fully understand how it might impact mental health.

Risks and Side Effects:​

While methylene blue can offer health benefits, it is important to note potential risks:

• Overdose: High doses of methylene blue can cause serious side effects, including nausea, vomiting, confusion, and even more severe reactions like serotonin syndrome (especially when combined with certain medications like antidepressants).
• Coloration of Urine: It can turn the urine a blue or green color, which is harmless but can be alarming.
• Interaction with Medications: Methylene blue can interact with certain medications, including monoamine oxidase inhibitors (MAOIs) and selective serotonin reuptake inhibitors (SSRIs), leading to a risk of serotonin syndrome, a potentially dangerous condition.
• G6PD Deficiency: People with glucose-6-phosphate dehydrogenase (G6PD) deficiency should avoid methylene blue, as it can cause hemolysis (destruction of red blood cells).

Dosage and Administration:​

• The exact dosage and form depend on the specific health condition being treated, and it should always be used under medical supervision.
• For methemoglobinemia, the typical dose is around 1–2 mg/kg administered intravenously. For cognitive or neuroprotective uses, lower doses might be explored, but these uses are still under investigation.

Conclusion:​

While methylene blue has potential therapeutic effects for various conditions, including cognitive health, methemoglobinemia, and infection treatment, its use should be carefully monitored, especially given its potential for serious side effects at high doses or when combined with other medications. Always consult a healthcare professional before using methylene blue for any health-related purpose.


Anyone use it? Opinions. Useful or waste of money?

Thanks.

 

[Pigsy]

Yes, just started this week. Has increased energy less brain fog. Will post up more after a few more weeks of use. It had turned my urine slight greenish.

 

[Eddie Haskell]

What is the TLDR on this supplement that seems to be in the news?

From Amazon

• PHARMACEUTICAL GRADE METHYLENE BLUE: Methylene Blue for clinical applications is the purest grade available & helps boost the energy production capabilities of mitochondria and may also protect against neurodegenerative disorders and memory loss
• MEMORY DEFENSE: Harness the power of antioxidants in our top-tier pharmaceutical grade methylene blue to combat cellular aging and support cognitive health
• EXACT CONCENTRATION AND ASSURED QUALITY: Boasting 99.9% purity, each of blue methylene drops delivers a precise 0.5mg dose, ensuring consistent strength for accurate application in therapeutic settings
• HIGHEST QUALITY: Trust in the exceptional purity and strength of our methylene blue usp consumption, rigorously tested and free from formaldehyde, adhering to US Pharmacopeia standards
• SECURE & CONVENIENT PACKAGING: Our methylene blue is packaged in glass bottles designed for easy dispensing. This packaging choice helps maintain the compound's potency, which can be compromised when stored in plastic containers

Chat-GPT
Methylene blue has several potential health benefits, though its use in medicine requires caution, as it can have side effects if not administered correctly. Here's a more detailed look at its health-related uses:

1.​

• What it is: Methemoglobinemia is a condition where hemoglobin, the molecule that carries oxygen in the blood, becomes oxidized and unable to effectively release oxygen to tissues.
• How methylene blue helps: Methylene blue works as a reducing agent, converting methemoglobin back to its normal form (hemoglobin), thus improving the oxygen-carrying capacity of the blood. It is commonly used in emergencies to treat this condition.
• Administration: It is typically administered intravenously in hospitals under medical supervision.

2.​

• Cognitive Function and Alzheimer's Disease: Research has been investigating methylene blue’s role in protecting neurons and improving brain function. Some studies suggest that it might help in diseases like Alzheimer’s by reducing oxidative stress, which can damage brain cells.
• Mitochondrial Health: Methylene blue has been found to support mitochondrial function. Since mitochondria are the powerhouses of cells, improving their function may help protect against cognitive decline and age-related diseases.
• Memory Enhancement: Some studies suggest that at low doses, methylene blue might improve memory and cognitive function, potentially offering benefits for those with cognitive impairment, though these effects are still being studied.

3.​

• Methylene blue has antioxidant effects, helping to neutralize free radicals and reduce oxidative stress in the body. This property may contribute to its potential neuroprotective effects and general health benefits, especially for conditions associated with oxidative damage.

4.​

• Methylene blue has been used historically to treat infections due to its antimicrobial properties. It can be effective against some bacteria and fungi, although it is not commonly used as a primary treatment today.
• It has also been used to treat urinary tract infections and as a topical antiseptic in certain cases.

5.​

• Methylene blue has been used in combination with other drugs to treat UTIs. It works by acting as a mild antiseptic, though more effective and targeted treatments are generally preferred for UTI management.

6.​

• Some preliminary studies have explored the use of methylene blue in cancer therapy. It has been shown to induce apoptosis (programmed cell death) in some cancer cells, and its ability to enhance mitochondrial function might also make it useful in preventing cancer cell survival. However, this is still an emerging area of research and should not be considered a standard cancer treatment.

7.​

• Some studies suggest that methylene blue may have an impact on mood and energy levels due to its role in mitochondrial function and its effects on brain chemistry. However, these effects are not well established and more research is needed to fully understand how it might impact mental health.

Risks and Side Effects:​

While methylene blue can offer health benefits, it is important to note potential risks:

• Overdose: High doses of methylene blue can cause serious side effects, including nausea, vomiting, confusion, and even more severe reactions like serotonin syndrome (especially when combined with certain medications like antidepressants).
• Coloration of Urine: It can turn the urine a blue or green color, which is harmless but can be alarming.
• Interaction with Medications: Methylene blue can interact with certain medications, including monoamine oxidase inhibitors (MAOIs) and selective serotonin reuptake inhibitors (SSRIs), leading to a risk of serotonin syndrome, a potentially dangerous condition.
• G6PD Deficiency: People with glucose-6-phosphate dehydrogenase (G6PD) deficiency should avoid methylene blue, as it can cause hemolysis (destruction of red blood cells).

Dosage and Administration:​

• The exact dosage and form depend on the specific health condition being treated, and it should always be used under medical supervision.
• For methemoglobinemia, the typical dose is around 1–2 mg/kg administered intravenously. For cognitive or neuroprotective uses, lower doses might be explored, but these uses are still under investigation.

Conclusion:​

While methylene blue has potential therapeutic effects for various conditions, including cognitive health, methemoglobinemia, and infection treatment, its use should be carefully monitored, especially given its potential for serious side effects at high doses or when combined with other medications. Always consult a healthcare professional before using methylene blue for any health-related purpose.


Anyone use it? Opinions. Useful or waste of money?

Thanks.

Interesting write up. I bought methylene blue used it once, just felt shady to me and didnt use it again. I'd like to see user feedback more on it from the EVO family.

@AE1079 what do you think about it?

Yes, just started this week. Has increased energy less brain fog. Will post up more after a few more weeks of use. It had turned my urine slight greenish.

Would be good to add this to your log.

 

[AE1079]

Interesting write up. I bought methylene blue used it once, just felt shady to me and didnt use it again. I'd like to see user feedback more on it from the EVO family.

@AE1079 what do you think about it?


Would be good to add this to your log.

With the above info around the product my anecdote is the same as Pigsy’s.

Less brain fog and clarity of memory and recall has increased substantially. My memory is extremely vivid even old memories are super clear. It’s quite surreal to be honest in that regard.

Urine is greenish but that’s expected as it’s a dye.

Overall gut health - can feel somewhat squeamish when I first have it the morning but then does a good flush during the day, mustn’t be used in high doses. My mood has improved significantly as well.

 

[Pigsy]

I could ran a log on it. As long as you can put up with the blue tongue pics

 

[Eddie Haskell]

With the above info around the product my anecdote is the same as Pigsy’s.

Less brain fog and clarity of memory and recall has increased substantially. My memory is extremely vivid even old memories are super clear. It’s quite surreal to be honest in that regard.

Urine is greenish but that’s expected as it’s a dye.

Overall gut health - can feel somewhat squeamish when I first have it the morning but then does a good flush during the day, mustn’t be used in high doses. My mood has improved significantly as well.

My concerns are the sides, what side effects long term.
I heard cancer talk.

 

[AE1079]

My concerns are the sides, what side effects long term.
I heard cancer talk.

Yeah there isn’t a lot of data on this - would like to know where the cancer stuff comes from though and how it would induce it

 

[Eddie Haskell]

Yeah there isn’t a lot of data on this - would like to know where the cancer stuff comes from though and how it would induce it

Thats what I was thinking “how”

 

[AE1079]

Thats what I was thinking “how”

Will deep dive, looking at its effects I would wonder how it would create cancer cells as it’s meaning to kill already harmful bacteria and pathogens. Let’s see - it has been used in the medical field for sometime for cyanide poisoning and all hospitals do have methylene blue as a IV medication in high doses, the dosing we are using ranges from 10-20 as an effective dose

 

[Eddie Haskell]

Will deep dive, looking at its effects I would wonder how it would create cancer cells as it’s meaning to kill already harmful bacteria and pathogens. Let’s see - it has been used in the medical field for sometime for cyanide poisoning and all hospitals do have methylene blue as a IV medication in high doses, the dosing we are using ranges from 10-20 as an effective dose

I was thinking it kills good bacteria as well, disrupting gut biome and leading to cancers.

I was watching @dylangemelli Dylan bio hacking interview and interesting they link gut biome to a lot and I agree there is research on this.

 

[AE1079]

I was thinking it kills good bacteria as well, disrupting gut biome and leading to cancers.

I was watching @dylangemelli Dylan bio hacking interview and interesting they link gut biome to a lot and I agree there is research on this.

I also heard that too. It would make sense, it wouldn’t just take bad bacteria with it, like t3 for example - it doesn’t discriminate what energy it burns. But I do know this will happen in the higher doses. Again we also don’t have clarity on specific dosing, we only have IV studied dosing which isn’t appropriate for us. So far I can recommend safe dosing is 10-20mg - but as far as gut bacteria we will need testing

 

[Eddie Haskell]

I also heard that too. It would make sense, it wouldn’t just take bad bacteria with it, like t3 for example - it doesn’t discriminate what energy it burns. But I do know this will happen in the higher doses. Again we also don’t have clarity on specific dosing, we only have IV studied dosing which isn’t appropriate for us. So far I can recommend safe dosing is 10-20mg - but as far as gut bacteria we will need testing

I’m talking to @LevButlerov about it, let’s see what he says, gut bacteria are my concern

 

[stevesmi]

I'm always skeptical about these types of supplements that promise the world

They can Market the crap out of anything and make it seem like it's something better than it is

 

[Mobster]

First time hearing about it

 

[willipede]

Good to hear your annecdotes boys. Haven't heard it mentioned in a few years, I would be concerned of anything that throws off the gut biome for regular use but this can be dose dependent and sometimes beneficial.

 

[ceo]

Bros. This is a cool write-up You put together.
Seems like it's more popular in Australia.

 

[ROIDDERS]

There's so many different supplements out there.

It's such a diluted industry.

 

[chesty]

Would be something that you guys should definitely log.
See if it works out well for you.

 

[Ulter]

Give it a shot. I mean, if it doesn't work, just send it back.

Amazon is pretty good when it comes to return policy.

 

[StevenDarwinMD]

LOG APPROVED - PLEASE POST A LOG