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Community Research Retatrutide - it’s the real deal

Threads marked with the 'Community Research' prefix involve ongoing research, high-quality logs, or in-depth community discussions backed by experience, data, or expert input.
Feelin any btr
 
drlifter said:
hey lads - just got my reta

are you guys diluting it with 2ml of bac in the 10mg vials?

just wondering how most are doing it
Click to expand...
@Drifter its simple math man.

if you have 10mg and do 1ML then each .1ML you extract will be 1mg. if you do 2ML of water then each .1ml you will extract will be .5mg and so on.
 
rustle said:
I was taking 1mg of reta EOD. The appetite suppression was excellent, hated the thought of food. Had zero desire to eat or ingest anything bad for me.
I was not losing ANY weight at all though (gaining infact), despite being in a caloric deficit (per my food logs).

As far as sides go, i was experiencing heartburn on a near daily basis. It would come and go but really made eating and training difficult. At times it would be so bad it was near (and actual once) vomit inducing.

Additionally i was experiencing a sensation in my skin, particularly below the waist where it felt really "hypersensitive". Not painful, but where it was like every hair on my legs could feel every fibre of my clothing at all times.

I've now skipped two doses of reta and the heartburn hasnt returned yet. The hypersensitive skin feeling has also subsided. Im going to stay off the reta until sunday and try re-introducing at 0.5mg OED to see if any sides return.
Click to expand...
@rustle retatrutide feedback
https://www.evolutionary.org/forums/threads/my-test-e-and-retatrutide-cycle-log.104587/post-1748463

This is not usual, it is possible he didn't have the actual retatrutide peptide.
 
Fellas jesus christ

Took my first 2mg intake yesterday

This shit is no joke - and by no joke, I mean I literally have zero appetite, and hate the thought of food!

Not saying that in a bad way, just surprised at how hard it hits you.

Do the sides such as appetite, feeling a bit nauseous, etc subside once you get a bit more used to it?
 
drlifter said:
Fellas jesus christ

Took my first 2mg intake yesterday

This shit is no joke - and by no joke, I mean I literally have zero appetite, and hate the thought of food!

Not saying that in a bad way, just surprised at how hard it hits you.

Do the sides such as appetite, feeling a bit nauseous, etc subside once you get a bit more used to it?
Click to expand...
yeah lad, reta is the LEAST side effect glp1, give it a few days youll befine, its only cause you started too high, 1mg is safer and titrate up
 
I agree to work your way so you can ease into the side

Example yesterday I cracked open a small coconut and started eating it and I couldn’t even finish my 4th bite. And had some naseua. Was fine 15 minutes later. You won’t be able to eat a big meal on it and take in lots of calories fast

Had I been on a higher dose too early I would have likely kept eating and ended up in trouble 👿
 
stevesmi said:
I agree to work your way so you can ease into the side

Example yesterday I cracked open a small coconut and started eating it and I couldn’t even finish my 4th bite. And had some naseua. Was fine 15 minutes later. You won’t be able to eat a big meal on it and take in lots of calories fast

Had I been on a higher dose too early I would have likely kept eating and ended up in trouble 👿
Click to expand...
Retatrutide works, and I can see you're really getting benefits. Less food and more time for yourself. @stevesmi
 
Oracle911 said:
yeah lad, reta is the LEAST side effect glp1, give it a few days youll befine, its only cause you started too high, 1mg is safer and titrate up
Click to expand...

Crazy bro.

I shoulda gone 1mg, ahh well. Throw myself in the deepend!

Been insane how little appetite/want for food... Almost worrying at this stage haha.

Cravings completely gone for absolutely everything that is bad though which is also insane to me.

Reta is the truth!
 
drlifter said:
Crazy bro.

I shoulda gone 1mg, ahh well. Throw myself in the deepend!

Been insane how little appetite/want for food... Almost worrying at this stage haha.

Cravings completely gone for absolutely everything that is bad though which is also insane to me.

Reta is the truth!
Click to expand...
nah youll be fine man, half life is around 5 -7 days but after a while it can linger in your system, through trial and error, as i dropped my dosage down after being on 2mg for a while, and even 2 weeks later i still had mild appetite suppresion, but i had been on for around 6 months, if you just started youll be sweet pretty quick, i have clients on 1mg and they start getting hungry by 7 days sometimes
 
Freki said:
https://www.theguardian.com/society...to-original-weight-within-year-analysis-finds GLPs dont keep the weight off
Click to expand...
100%. which is why you should already have your diet/training on point before hopping on these.

same thing with steroids. you gain a ton of strength on tren, you are going to lose a lot of it back when you come off. but if you have a good base you will be able to build on those gains

there is also an element with GLP1's which is should you stay on a maintenance dose going forward, similar to what you would do with TRT situations.
 
drlifter said:
Crazy bro.

I shoulda gone 1mg, ahh well. Throw myself in the deepend!

Been insane how little appetite/want for food... Almost worrying at this stage haha.

Cravings completely gone for absolutely everything that is bad though which is also insane to me.

Reta is the truth!
Click to expand...
cravings are all hormonal bro @drlifter you should start a retatrutide log and keep your experience and fat loss up
why havent you gotten it up? EVO family waiting
 
Oracle911 said:
nah youll be fine man, half life is around 5 -7 days but after a while it can linger in your system, through trial and error, as i dropped my dosage down after being on 2mg for a while, and even 2 weeks later i still had mild appetite suppresion, but i had been on for around 6 months, if you just started youll be sweet pretty quick, i have clients on 1mg and they start getting hungry by 7 days sometimes
Click to expand...
Usually appetite comes back around day 7 when guys get off retatrutide.
 
Oracle911 said:
Agreed. Depends on persons tolerance and clearance rate. Also how long they have been on how much. Generally would agree roughly 7 days :)
Click to expand...
I hope to see a better transition, example retatrutide pyramid down to control appetite. @Oracle911
 
Freki said:
I'm going cold turkey now , another anecdotal account. Going to he very interesting how the hunger rebounds
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There was a study which involved 15000 people on sema that showed 11 pound drop after 6 months. Then another 7 pound drop the next 6 months but the placebo group gained back 8 pounds. My numbers might be off a bit as I don’t have the study in front of me but the point is there is definitely a rebound effect that people should expect

Also there was a risk of pancreas and thyroid issues in those that stayed on for a prolonged period time. So it’s one of those things like steroids that there are some risks
 
Oracle911 said:
yeah lad, reta is the LEAST side effect glp1, give it a few days youll befine, its only cause you started too high, 1mg is safer and titrate up
Click to expand...

Yeah realised that. I'm all good now. 7 day mark today and I feel pretty good.

Do you reckon I just sustain 2mg from here?

Or go back to 1mg?
 
drlifter said:
Yeah realised that. I'm all good now. 7 day mark today and I feel pretty good.

Do you reckon I just sustain 2mg from here?

Or go back to 1mg?
Click to expand...
if you feel fine on 2mg and its doing everything you need then you can stay at 2mg, if you wanted to save some money no harm in going down to 1.5mg then reassessing, will stay with you for 7 days, whats overall goal?
 
Oracle911 said:
if you feel fine on 2mg and its doing everything you need then you can stay at 2mg, if you wanted to save some money no harm in going down to 1.5mg then reassessing, will stay with you for 7 days, whats overall goal?
Click to expand...
Drop weight fast - so I'll stick with 2mg - was just a shock to begin but was fine the rest of the week.

If the 2mg doesn't feel right this week, I'll drop it - but best guess is that ill be fine given its 2nd week now
 
drlifter said:
Yeah realised that. I'm all good now. 7 day mark today and I feel pretty good.

Do you reckon I just sustain 2mg from here?

Or go back to 1mg?
Click to expand...
drlifter said:
Drop weight fast - so I'll stick with 2mg - was just a shock to begin but was fine the rest of the week.

If the 2mg doesn't feel right this week, I'll drop it - but best guess is that ill be fine given its 2nd week now
Click to expand...
stay on 2mgs of retatrutide broly @drlifter
you should cut to 1mg if you get sides though

listen what happened to your log? i see no updates there on food
https://www.evolutionary.org/forums/threads/my-tesamorelin-semaglutide-cycle-log.99200/
 
Increasing psyllium husk intake to 3x/day around 20 grams/day got rid of heart burn side effects for @rustle
https://www.evolutionary.org/forums/threads/my-test-e-and-retatrutide-cycle-log.104587/post-1754188
rustle said:
Really good day today. Felt strong with a few improvements on a some lifts. Stamina still isnt there for some of the sets but overall please with the day. No heartburn symptoms from the reta yet. Have upped the metamucil (psyllium husk) to 20g/day on @LevButlerov's advice. Poo'd 2 or 3 times today.
Click to expand...
Another point of evidence that psyllium husk, probiotics and digestive enzymes are a must with GLP-1 peptides like retatrutide, semaglutide and tirzapetide.
 
@michaelvcurci taking 1.5-2mgs of retatrutide confirmation of dose

https://www.evolutionary.org/forums...-napsgear-isnt-responding.104900/post-1758108
michaelvcurci said:
I just wanted to say thank you man, really appreciate it, been at a loss at what to do. So for my current cycle, I am taking 500 test c, 300 npp EOD, and might sound funny but I'm also taking 1.5-2mg retatrutide a week. I know most people use the Nandrone for bulks but I feel its also been helping me cut fat while still growing. I have my next order ready though, its gonna be test mast/primo and anavar. Im still deciding on the dosages, if you had any input, would be much appreciated.
Click to expand...
 
@rustle took 1 big dose of retatrutide vs microdose, his views
https://www.evolutionary.org/forums/threads/my-test-e-and-retatrutide-cycle-log.104587/post-1762050
rustle said:
Sorry guys. been offline for a bit. Still been training and logging though.


Not intentionally. I find that the reta by nature makes me though.

Speaking of which, i took a 4mg dose of reta all at once on sunday night. Going to try single weekly shot vs EOD. There's lots of different opinions on single vs micro dosing and i'd like to seek how it affects me personally from a symptoms perspective. Its day 2 since the injection and i honestly feel no different compared to micro dosing, I can say that since i took a week off between 11 and 18 May that the recommencement of reta has not had the same drastic effect on appetite suppression as it did previously. I can also enjoy a full meal which makes me happy.

Whether it was the break, the fact that ive now been taking reta for about 7 weeks, the metamucil/psyllium husk helping digestion or a combination of all the above, not sure. Lets seen how things progress from here.

As of weigh in day yesterday, weight was 91.7kg which is back to what i was when i started the cycle.
Click to expand...
 
Thanks @LevButlerov sorry i havent updated my specific experience here.

My reta experience while on Test E cycle 150mg EOD and average caloric intake of 1600-1700cals:

First 4 weeks of reta @ 1mg EOD (source 1)
Zero weight loss, weight gain actually, Great appetite suppression, hated the thought of food. Struggled to eat a full meal.
Sides:
  • Regular heartburn, sometimes to the point of vomitting.
  • Hypersensitive skin below the waist - this would go away during exercising
Weeks 5 & 6 @ 1mg EOD (source 2)
Tried reta from a second source. Just to see if there was anything different given i hadnt lost any weight. No discernable difference in effects or sides.

Week 7 took a break from Reta

Week 8 to 10 @0.5mg (source 2)
Recommenced reta at a lower dose to judge what side effects were like. Appetite suppression has reduced. I can eat a proper meal without feeling like sh!t after. The suppression is still there, but i can eat if and when i want to.
Sides:
  • Heartburn occurences were significantly less and more manageable when they occurred
  • Hypersensitive skin camne back in the second week. Its not a problem, just a strange, "always there' feeling.
Treatments possibly linked to reducing heartburn:
  • Upped my intake of psyllium husk (metamucil) from 7g a day to 20g
  • Started drinking electrolytes throughout the day/night, with 1 tablespoon of apple cider vinegar per drink.
Week 11 (now)
Took single dose of 4mg 3 days ago. Havent felt any difference compared to a lower micro dose. Havent had any heartburn. Following the second day though, my sleep has been impacted. I go to bed at 11pm and am waking up between 4 and 5am, Im then unable to fall back asleep easily. It;s a "broken rest" up until i get up at 7am.
This is conflated by a full bladder due to trying to keep my water and electrolyte intake right up there to prevent heartburn, and having a PWO shake around 9:30pm.
 
rustle said:
Thanks @LevButlerov sorry i havent updated my specific experience here.

My reta experience while on Test E cycle 150mg EOD and average caloric intake of 1600-1700cals:

First 4 weeks of reta @ 1mg EOD (source 1)
Zero weight loss, weight gain actually, Great appetite suppression, hated the thought of food. Struggled to eat a full meal.
Sides:
  • Regular heartburn, sometimes to the point of vomitting.
  • Hypersensitive skin below the waist - this would go away during exercising
Weeks 5 & 6 @ 1mg EOD (source 2)
Tried reta from a second source. Just to see if there was anything different given i hadnt lost any weight. No discernable difference in effects or sides.

Week 7 took a break from Reta

Week 8 to 10 @0.5mg (source 2)
Recommenced reta at a lower dose to judge what side effects were like. Appetite suppression has reduced. I can eat a proper meal without feeling like sh!t after. The suppression is still there, but i can eat if and when i want to.
Sides:
  • Heartburn occurences were significantly less and more manageable when they occurred
  • Hypersensitive skin camne back in the second week. Its not a problem, just a strange, "always there' feeling.
Treatments possibly linked to reducing heartburn:
  • Upped my intake of psyllium husk (metamucil) from 7g a day to 20g
  • Started drinking electrolytes throughout the day/night, with 1 tablespoon of apple cider vinegar per drink.
Week 11 (now)
Took single dose of 4mg 3 days ago. Havent felt any difference compared to a lower micro dose. Havent had any heartburn. Following the second day though, my sleep has been impacted. I go to bed at 11pm and am waking up between 4 and 5am, Im then unable to fall back asleep easily. It;s a "broken rest" up until i get up at 7am.
This is conflated by a full bladder due to trying to keep my water and electrolyte intake right up there to prevent heartburn, and having a PWO shake around 9:30pm.
Click to expand...
where did you get your reta from?

its possible you got something else who knows

there are plenty of people who use these glp-1's and don't get very good results. it just might not agree with you.
 
stevesmi said:
where did you get your reta from?

its possible you got something else who knows

there are plenty of people who use these glp-1's and don't get very good results. it just might not agree with you.
Click to expand...
Two different sources. @Sydneycitysupplements and @Raptor Labs . I trust both wholeheartedly and based on the sides have zero doubt in my mind that ive been supplied reta. It's possible that it's just not the right GLP-1 for me, but im going to stick with it after the test e cycle finishes and until my supply of reta finishes.
 
rustle said:
Two different sources. @Sydneycitysupplements and @Raptor Labs . I trust both wholeheartedly and based on the sides have zero doubt in my mind that ive been supplied reta. It's possible that it's just not the right GLP-1 for me, but im going to stick with it after the test e cycle finishes and until my supply of reta finishes.
Click to expand...
i'm assuming your diet was on point. you mentioned calories. but quality matters too and so does exercising. in studies the people involved were put on diets and had regular exercise.
 
T-RexAlpha said:
Whats your experience been? Do you have a log of your experiences? I would love to see it
Click to expand...
Check my log man. And check the podcasts where I talk about how it works and studies
 
rustle said:
Thanks @LevButlerov sorry i havent updated my specific experience here.

My reta experience while on Test E cycle 150mg EOD and average caloric intake of 1600-1700cals:

First 4 weeks of reta @ 1mg EOD (source 1)
Zero weight loss, weight gain actually, Great appetite suppression, hated the thought of food. Struggled to eat a full meal.
Sides:
  • Regular heartburn, sometimes to the point of vomitting.
  • Hypersensitive skin below the waist - this would go away during exercising
Weeks 5 & 6 @ 1mg EOD (source 2)
Tried reta from a second source. Just to see if there was anything different given i hadnt lost any weight. No discernable difference in effects or sides.

Week 7 took a break from Reta

Week 8 to 10 @0.5mg (source 2)
Recommenced reta at a lower dose to judge what side effects were like. Appetite suppression has reduced. I can eat a proper meal without feeling like sh!t after. The suppression is still there, but i can eat if and when i want to.
Sides:
  • Heartburn occurences were significantly less and more manageable when they occurred
  • Hypersensitive skin camne back in the second week. Its not a problem, just a strange, "always there' feeling.
Treatments possibly linked to reducing heartburn:
  • Upped my intake of psyllium husk (metamucil) from 7g a day to 20g
  • Started drinking electrolytes throughout the day/night, with 1 tablespoon of apple cider vinegar per drink.
Week 11 (now)
Took single dose of 4mg 3 days ago. Havent felt any difference compared to a lower micro dose. Havent had any heartburn. Following the second day though, my sleep has been impacted. I go to bed at 11pm and am waking up between 4 and 5am, Im then unable to fall back asleep easily. It;s a "broken rest" up until i get up at 7am.
This is conflated by a full bladder due to trying to keep my water and electrolyte intake right up there to prevent heartburn, and having a PWO shake around 9:30pm.
Click to expand...
i'm gonna talk about your experience on our podcast. it is interesting
one of the things that doesn't make any sense to me

1. you are eating very little calories
2. you are having your appetite suppressed

those 2 things alone would yield weight loss obviously

my suggestion after re-reading is dump all the electrolyte drinks, a lot them contain tons of junk and fillers/sugar. stop drinking protein shakes PWO late. that alone can cause major stomach issues. drop your test dose to weekly like a trt dose. and finally i would stop the psyllium husk which can do more harm then good.
just drink water and eat 2-3 clean meals a day and i bet you will start dropping weight fast. i bet a lot of your weight issues here are due to bloating, too much water retention and too much test.. i mean you are using like 500mgs a week test and that alone can cause a 10-15lb water weight increase
 
stevesmi said:
i'm gonna talk about your experience on our podcast. it is interesting
one of the things that doesn't make any sense to me

1. you are eating very little calories
2. you are having your appetite suppressed

those 2 things alone would yield weight loss obviously

my suggestion after re-reading is dump all the electrolyte drinks, a lot them contain tons of junk and fillers/sugar. stop drinking protein shakes PWO late. that alone can cause major stomach issues. drop your test dose to weekly like a trt dose. and finally i would stop the psyllium husk which can do more harm then good.
just drink water and eat 2-3 clean meals a day and i bet you will start dropping weight fast. i bet a lot of your weight issues here are due to bloating, too much water retention and too much test.. i mean you are using like 500mgs a week test and that alone can cause a 10-15lb water weight increase
Click to expand...
Waiting to see this on the podcast. :D will be interesting. @stevesmi
 
stevesmi said:
i'm gonna talk about your experience on our podcast. it is interesting
one of the things that doesn't make any sense to me

1. you are eating very little calories
2. you are having your appetite suppressed

those 2 things alone would yield weight loss obviously

my suggestion after re-reading is dump all the electrolyte drinks, a lot them contain tons of junk and fillers/sugar. stop drinking protein shakes PWO late. that alone can cause major stomach issues. drop your test dose to weekly like a trt dose. and finally i would stop the psyllium husk which can do more harm then good.
just drink water and eat 2-3 clean meals a day and i bet you will start dropping weight fast. i bet a lot of your weight issues here are due to bloating, too much water retention and too much test.. i mean you are using like 500mgs a week test and that alone can cause a 10-15lb water weight increase
Click to expand...
waiting on this podcast too.
There's alot about my experience that doesnt match up with alot of the current studies.
No rapid weight loss, no explosive poos etc. Everybody reacts differently to these things i suppose.

Interesting you suggest to come off the psyllium husk. @LevButlerov recommended i increase my intake to try and assist with digestion as a potential remedy to my heartburn issues. it *appears* to be having some effect, or it could be a number of factors combined with the total duration ive now been taking reta?

I can assure you that my intake tracking is what i am consuming (excluding the 5 calories per electrloyte mix). No sneaky little snacks or anything like that. Since coming off zoloft and starting training again (per my log) i have had laser sharp focus on my training and food.

The electrolyte drink i've been having is a total 5 calories per scoop. 0 sugar. I would have two of these a day, mixed with 1L water each time.
1749165559587.webp
 
rustle said:
waiting on this podcast too.
There's alot about my experience that doesnt match up with alot of the current studies.
No rapid weight loss, no explosive poos etc. Everybody reacts differently to these things i suppose.

Interesting you suggest to come off the psyllium husk. @LevButlerov recommended i increase my intake to try and assist with digestion as a potential remedy to my heartburn issues. it *appears* to be having some effect, or it could be a number of factors combined with the total duration ive now been taking reta?

I can assure you that my intake tracking is what i am consuming (excluding the 5 calories per electrloyte mix). No sneaky little snacks or anything like that. Since coming off zoloft and starting training again (per my log) i have had laser sharp focus on my training and food.

The electrolyte drink i've been having is a total 5 calories per scoop. 0 sugar. I would have two of these a day, mixed with 1L water each time.
View attachment 96722
Click to expand...
scan it with the yuka app and see what kind of junk is really in it. i haven't found a single electrolyte mix powder that wasn't full of garbage. and that won't help your situation
 
rustle said:
Thanks @LevButlerov sorry i havent updated my specific experience here.

My reta experience while on Test E cycle 150mg EOD and average caloric intake of 1600-1700cals:

First 4 weeks of reta @ 1mg EOD (source 1)
Zero weight loss, weight gain actually, Great appetite suppression, hated the thought of food. Struggled to eat a full meal.
Sides:
  • Regular heartburn, sometimes to the point of vomitting.
  • Hypersensitive skin below the waist - this would go away during exercising
Weeks 5 & 6 @ 1mg EOD (source 2)
Tried reta from a second source. Just to see if there was anything different given i hadnt lost any weight. No discernable difference in effects or sides.

Week 7 took a break from Reta

Week 8 to 10 @0.5mg (source 2)
Recommenced reta at a lower dose to judge what side effects were like. Appetite suppression has reduced. I can eat a proper meal without feeling like sh!t after. The suppression is still there, but i can eat if and when i want to.
Sides:
  • Heartburn occurences were significantly less and more manageable when they occurred
  • Hypersensitive skin camne back in the second week. Its not a problem, just a strange, "always there' feeling.
Treatments possibly linked to reducing heartburn:
  • Upped my intake of psyllium husk (metamucil) from 7g a day to 20g
  • Started drinking electrolytes throughout the day/night, with 1 tablespoon of apple cider vinegar per drink.
Week 11 (now)
Took single dose of 4mg 3 days ago. Havent felt any difference compared to a lower micro dose. Havent had any heartburn. Following the second day though, my sleep has been impacted. I go to bed at 11pm and am waking up between 4 and 5am, Im then unable to fall back asleep easily. It;s a "broken rest" up until i get up at 7am.
This is conflated by a full bladder due to trying to keep my water and electrolyte intake right up there to prevent heartburn, and having a PWO shake around 9:30pm.
Click to expand...
I've used 2mg a week on two occasions. First was 2mg once a week, the second was 1mg twice a week.

I had none of those side effects you mentioned and if you are not losing weight on 1600 cals you are either lying to yourself about caloric intake or are extremely small and not moving all day.
 
CreatineMONO said:
I've used 2mg a week on two occasions. First was 2mg once a week, the second was 1mg twice a week.

I had none of those side effects you mentioned and if you are not losing weight on 1600 cals you are either lying to yourself about caloric intake or are extremely small and not moving all day.
Click to expand...

Whilst i appreciate your candidness, i assure you there is no lying about my caloric intake. I'm extremely strict. I dont understand why people would lie about that? Its impossible to get sound, tailored advice on something if you're not even being truthful about what you are doing. Totally counter productive.
I have been logging my last 10-11 weeks of reta usage, food intake and training in my current cycle log. And whilst i do have a very sedentary work day, i train 4 days a week with the 5 day being dedicated to cardio.
I am sure i am gaining lean mass whilst also losing some BF, it's just not the results i tend to read about of others' experiences.
 
rustle said:
waiting on this podcast too.
There's alot about my experience that doesnt match up with alot of the current studies.
No rapid weight loss, no explosive poos etc. Everybody reacts differently to these things i suppose.

Interesting you suggest to come off the psyllium husk. @LevButlerov recommended i increase my intake to try and assist with digestion as a potential remedy to my heartburn issues. it *appears* to be having some effect, or it could be a number of factors combined with the total duration ive now been taking reta?

I can assure you that my intake tracking is what i am consuming (excluding the 5 calories per electrloyte mix). No sneaky little snacks or anything like that. Since coming off zoloft and starting training again (per my log) i have had laser sharp focus on my training and food.

The electrolyte drink i've been having is a total 5 calories per scoop. 0 sugar. I would have two of these a day, mixed with 1L water each time.
View attachment 96722
Click to expand...
@rustle to clarify, who is your retatrutide supplier? You're in Australia so it's a bit different.
 
rustle said:
Whilst i appreciate your candidness, i assure you there is no lying about my caloric intake. I'm extremely strict. I dont understand why people would lie about that? Its impossible to get sound, tailored advice on something if you're not even being truthful about what you are doing. Totally counter productive.
I have been logging my last 10-11 weeks of reta usage, food intake and training in my current cycle log. And whilst i do have a very sedentary work day, i train 4 days a week with the 5 day being dedicated to cardio.
I am sure i am gaining lean mass whilst also losing some BF, it's just not the results i tend to read about of others' experiences.
Click to expand...
If you have been eating 1700 calories for 10-11 weeks and training that many times a week, you should have lost weight regardless of being on retatrutide or not. You would not be gaining enough lean mass to balance out what weight you should be losing. It just doesn't make sense.

Have you had complete bloods done recently including thyroid to check for Hypothyroidism?
 
CreatineMONO said:
I've used 2mg a week on two occasions. First was 2mg once a week, the second was 1mg twice a week.

I had none of those side effects you mentioned and if you are not losing weight on 1600 cals you are either lying to yourself about caloric intake or are extremely small and not moving all day.
Click to expand...

Definitely this! And ill add to this... 1600 is low as fuck so it sounds like tracking is not accurate
 
Flyingandrei said:
Definitely this! And ill add to this... 1600 is low as fuck so it sounds like tracking is not accurate
Click to expand...
Tracking is accurate. No cheat meals. No alcohol. No little snacks in-between what I log.

Believe me, I am as confused as everyone else. I have always struggled with my weight. Before starting this cycle, I would often only eat dinner and somehow still put on weight. And no it wasn't stuffing myself with whole pizza and junk. Just a normal homecooked meal.

I've posted my most recent blood work in my log.
 
rustle said:
Tracking is accurate. No cheat meals. No alcohol. No little snacks in-between what I log.

Believe me, I am as confused as everyone else. I have always struggled with my weight. Before starting this cycle, I would often only eat dinner and somehow still put on weight. And no it wasn't stuffing myself with whole pizza and junk. Just a normal homecooked meal.

I've posted my most recent blood work in my log.
Click to expand...
You had brands changes in the retatrutide? during the cycle @rustle
 
Those are very basic bloods. If you are aren't losing weight on 1700 cals and reta AND have had weight gain issues in the past I would be getting a comprehensive blood panel. BB3 from Imedical for example.

Gaining weight while eating 1 meal of what I assume would be under 1000 calories defies logic unless there is a disease I am unaware of that would cause that. Not saying you're lying but things don't add up. I'm more concerned what is going on that could be causing that if you're being 100
rustle said:
Tracking is accurate. No cheat meals. No alcohol. No little snacks in-between what I log.

Believe me, I am as confused as everyone else. I have always struggled with my weight. Before starting this cycle, I would often only eat dinner and somehow still put on weight. And no it wasn't stuffing myself with whole pizza and junk. Just a normal homecooked meal.

I've posted my most recent blood work in my log.
Click to expand...
 
rustle said:
Tracking is accurate. No cheat meals. No alcohol. No little snacks in-between what I log.

Believe me, I am as confused as everyone else. I have always struggled with my weight. Before starting this cycle, I would often only eat dinner and somehow still put on weight. And no it wasn't stuffing myself with whole pizza and junk. Just a normal homecooked meal.

I've posted my most recent blood work in my log.
Click to expand...
LevButlerov said:
I doubt @CreatineMONO is lying, but we didn't see his log so mistracking possible.
@Flyingandrei
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Not being rude but i still don't believe it. If you aren't losing then your not in a deficit. So my takeaway is either again...

1. Not tracking properly every lick, bite, condiments, liquids

Or

2. Youve ruined your metabolism so bad that your maintenance calories is far lower than 1600 resulting in you not being able to lose anything.

I just took on a client 50 years old. Natural 23% bodyfat, in almost 4 weeks he has lost 3kg. No crazy cardio. Just tracking overall calories. He's not even doing macros.

Just saying. Not losing then your calories are not accurate.
 
rustle said:
Whilst i appreciate your candidness, i assure you there is no lying about my caloric intake. I'm extremely strict. I dont understand why people would lie about that? Its impossible to get sound, tailored advice on something if you're not even being truthful about what you are doing. Totally counter productive.
I have been logging my last 10-11 weeks of reta usage, food intake and training in my current cycle log. And whilst i do have a very sedentary work day, i train 4 days a week with the 5 day being dedicated to cardio.
I am sure i am gaining lean mass whilst also losing some BF, it's just not the results i tend to read about of others' experiences.
Click to expand...

Are you doing any step count? Any cardio at all? Log up your my fitness pal daily eating.

Show us calories plus carbs, fat, protein, fiber. Show us Monday - Sunday. Not accusing but i had clients in the past that said tracking accurate and it was way off.

Tracking wrong brands eg lean mince vs normal mince (can throw calories way off) I told my other client off tonight because he was tracking pasta and mince and putting in generic and choosing the lower calorie options (my fitness pal.

I actually totalled it for him. He got 450 calories it was 750 calories. Add that up over the week.

2100 extra calories would blow someone over their deficit
 
Freki said:
Maybe ultra slow metabolism isn't a myth just ultra extremely rare
Click to expand...

Before it can be ruled out need to see proper log for at least 2 weeks consistency. Ive had people with all different kinds of metabolism but still...

Calories never lied. Ive had people with diabetes, gout issues etc still all lost weight tracking.

Just my 2 cents and experience. Take it or leave it to the poster.
 
Flyingandrei said:
Are you doing any step count? Any cardio at all? Log up your my fitness pal daily eating.

Show us calories plus carbs, fat, protein, fiber. Show us Monday - Sunday. Not accusing but i had clients in the past that said tracking accurate and it was way off.

Tracking wrong brands eg lean mince vs normal mince (can throw calories way off) I told my other client off tonight because he was tracking pasta and mince and putting in generic and choosing the lower calorie options (my fitness pal.

I actually totalled it for him. He got 450 calories it was 750 calories. Add that up over the week.

2100 extra calories would blow someone over their deficit
Click to expand...
I have a log: https://www.evolutionary.org/forums/threads/my-test-e-and-retatrutide-cycle-log.104587/
I use myfitnesspal already. I put everything in there.

My maintenance calories should be aroune 2100. I am not eating that. There arent some hidden 500-600 hidden calories in the non-existant food im not eating.

At this point ive reinforced my position so many times, i cant be bothered trying to further explain myself in this thread. My food is logged correctly, my training is logged, my cardio is logged. My PED usage and Reta usage is logged. Im tired of reading people's disbelief in what im saying and having to try justify things over and over again.

At this point, i'm done with this thread. Believe me or not. Whatever. Hoping atleast someday someone else might read my experience and be able to relate to it.
 
rustle said:
I have a log: https://www.evolutionary.org/forums/threads/my-test-e-and-retatrutide-cycle-log.104587/
I use myfitnesspal already. I put everything in there.

My maintenance calories should be aroune 2100. I am not eating that. There arent some hidden 500-600 hidden calories in the non-existant food im not eating.

At this point ive reinforced my position so many times, i cant be bothered trying to further explain myself in this thread. My food is logged correctly, my training is logged, my cardio is logged. My PED usage and Reta usage is logged. Im tired of reading people's disbelief in what im saying and having to try justify things over and over again.

At this point, i'm done with this thread. Believe me or not. Whatever. Hoping atleast someday someone else might read my experience and be able to relate to it.
Click to expand...

No hate from me whatsoever 😊 just trying help you figure it out to see what is going wrong lastly i can only think of an autoimmune issues or underlying health issue.

I still stand by it though. If you aren't losing then you are not in a calorie deficit. So my last conclusion is you tanked your metabolism that your maintenance has caught up and you have a new set point of calories which is lower than you'd like.

Solution...Try a 1 day fast and see if you loose then a 3 day fast with guidance from @lev or @stevemsi. You would definitely be in a deficit then!

Have you ever had a diet break? Re feed day? You will figure this out man 👌🏼🔥
 
i have seen people on these not have success.
i agree trying fasting while on them. the nice thing about these GLP'1's is you wont' go hypo on them like other fat loss drugs. so you can absolutely fast, that might trigger some insulin sensitivity and get your body burning fat more effectively and kickstart things
 
Flyingandrei said:
No hate from me whatsoever 😊 just trying help you figure it out to see what is going wrong lastly i can only think of an autoimmune issues or underlying health issue.

I still stand by it though. If you aren't losing then you are not in a calorie deficit. So my last conclusion is you tanked your metabolism that your maintenance has caught up and you have a new set point of calories which is lower than you'd like.

Solution...Try a 1 day fast and see if you loose then a 3 day fast with guidance from @lev or @stevemsi. You would definitely be in a deficit then!

Have you ever had a diet break? Re feed day? You will figure this out man 👌🏼🔥
Click to expand...
Quick excerpt on the back of metabolism tanking
"Again findings vary, though in line with the Minnesota experiment which found a 15% adaptation the aforementioned Biggest Loser trial saw adaptations in resting metabolic rate of up to 18% when body composition was accounted for (5). Similarly the Biosphere 2 experiment (which was a fascinating idea – basically trying to see if people could live in a closed ecosystem) saw a reduction in resting metabolic rate adjusted for body composition of 10-15% after chronic underfeeding (1), but other studies found more modest numbers.

The CALERIE study which involved a 25% calorie deficit for 3-6 months found a reduction in TDEE of 6%, for example (6), and similar adaptations (5-7%) seem to be the most common findings (1). Taken together these data suggest that adaptation, when it occurs, seems to amount to between roughly 5-15% of resting metabolic rate, or roughly 50-180kcal per day total.

What is clear, however, that the maximal adaptation ever seen is roughly 18% (the Biggest Loser) while the average is between 5-15 (up to around 180kcal per day), with most studies finding adaptation in the single digits. This happens after at least two weeks of dieting, and the higher adaptation rates only seem to occur after 3-6 months of dietary restriction. Interestingly the MATADOR study published in 2018 (7) found that repeated rounds of two week diet/two week maintenance for 30 weeks achieved the same rate of weight loss as a 16 week continuous diet but with a much reduced level of adaptation, though far more work is needed in this area to be able to say for certain that this is a viable approach."

sourece: https://btn.academy/blog/metabolic-adaptation-weight-loss-science/

This suggests its not a matter of a slowed metabolism, but OP has had enough of this discussion so good luck to him: )
 
Flyingandrei said:
No hate from me whatsoever 😊 just trying help you figure it out to see what is going wrong lastly i can only think of an autoimmune issues or underlying health issue.

I still stand by it though. If you aren't losing then you are not in a calorie deficit. So my last conclusion is you tanked your metabolism that your maintenance has caught up and you have a new set point of calories which is lower than you'd like.

Solution...Try a 1 day fast and see if you loose then a 3 day fast with guidance from @lev or @stevemsi. You would definitely be in a deficit then!

Have you ever had a diet break? Re feed day? You will figure this out man 👌🏼🔥
Click to expand...
Please go @LevButlerov for your @ so I know you commented in future @Flyingandrei :D

Trying a 1 day fast is a start.
 
awm1981 said:
Wanted to give a quick update! I’ve been running gw501516 from PSL (europharma) and Naps (Pharmaqo) along with retatrutide from us peptides from Naps and now retatrutide from umbrella and the stack for a cut cycle is real.

Since November I’ve been taking the standard 20mg/day gw501516 and started the retatrutide at .25mg/week. I’ve since found the sweet spot of 1.5mg/week. Zero sides no nausea just not hungry which is great for me since I’m always hungry! In a little over 3.5 months I’ve dropped 20 pounds (was around 285 now I’m 265) with little to no strength loss.

The retatrutide is not a long term solution I’ll be cutting it out in the next few months once I get to around 250 to then kick off my test/primo/anavar run in May but it’s been a huge help to get me back on track weight wise!
Click to expand...
I'm currently microdosing reta (.5mg 3x per wk) on my first off-season bulk, to control insulin sensitivity and to minimise fat gain during. Only been a week but I feel great especially on my high carb days, looking full, hard, and having great fkn pumps at the gym.
 
@madcap71 posted his 2 weeks experience (short) with retatrutide
https://www.evolutionary.org/forums...e-primo-retatrutide-cycle.105362/post-1775390
madcap71 said:
My experience so far on reta, 2 weeks in.
Not much in terms of weight loss but I'm eating the same macros kcals as before.

I'm taking it mainly to suppress my ravenous hunger, post-show, so I'm not seeing the hardcore appetite suppression others do, however I want to eat my meals still, just want to eliminate food noise, which i feel it is doing very well.

Yesterday, I got into work after being up for 3 hours and I realised "oh. I haven't had my first meal yet', wasn't hungry for it but I still ate it and didn't think much about food at all. Which is a huge improvement, considering the post-show cravings I was having.

My food is likely to go up in the coming weeks, after my holiday so I will keep at 2mg a week. Hoping however, that Reta keeps my hunger grounded when on holiday as my hotel is half board and has a lovely buffet breakfast!
Click to expand...
 
@stevesmi veteran at fasting share his 16.5lbs loss on retatrutide in his log

https://www.evolutionary.org/forums...le-and-my-prolong-fast-log.81856/post-1776943
stevesmi said:
Okay so am doing update on my reta ride
I moved my dose back down to 2mgs. i've been alternating it as high as 2.4mgs
my current weight this morning is 162.6. had a really tough workout yesterday evening

wanted to report on some things that are happening to me on retatrutide as I am now a full 8 weeks into it

1. on days i train HARD and burn a ton of calories my appetite is very good. on days where i don't train as much or rest my appetite is very low like i can fast all day with zero hunger. the logic here is you burn a ton of fat the more you train. this stuff turns your body into a fat and calorie burning machine.
2. i notice i pee more on this stuff. I researched this and I believe this is similar to what happens while you are actually fasting. to dumb it down those fat stores have to go SOMEWHERE to get expelled and for me urinating it out is the way my body likes to do it. for others they might sweat it out or breathe it out. just an FYI CO2 is exhaled through lungs and H20 is excreted from urine and sweat. I'm not a huge sweater so for me urination is the way my body prefers to get rid of it. I get up at night and pee A LOT at once. and I also pee before bed and when i wake up.
what makes this very fascinating is I am NOT peeing out ketones like i would during a fast. so these GLP-1's are not putting you into ketosis yet i am still losing so much body fat. it is quite amazing.
3. my weight drops more after a strong cardio workout. so the more you train on this stuff the more you will lose
4. the studies on reta show a 20% loss of total body weight from those who use it 6 months. earlier someone said I was getting too lean on this stuff. well that IS sort of the point DUH. you don't use retatrutide to bulk. that would be like saying I'm going to use dbol to cut. it makes no sense. . I started out at 180 pounds so if i lose 20% of my body weight that would put me at 144 lol. I don't plan on getting THAT lean but it could happen. considering in 8 weeks i have lost around 16.5 pounds that is about 2 pounds a week. i expect that weight loss to slow down obviously.

anyone have any questions feel free to ask I can't think of anything else right now
Click to expand...
 
@madcap71 is reporting appetite suppression with retatrutide is taking time, didn't kick in right away -
https://www.evolutionary.org/forums...e-primo-retatrutide-cycle.105362/post-1778707

madcap71 said:
Up and down with the effects of reta. The appetite suppression isn't fully there yet.

Yesterday, I had a protein bar and a banana pre-workout but then couldn't train until 4 hours later, trained and then wasn't hungry for my post workout meal. So nearly 6 hours between meals which isn't like me. Then a few hours later I had a small (200g cod, 60g jasmine rice and spinach) meal, which filled me up a lot more than it should have

Had my weekly off plan meal later that evening (home made 5% beef burgers and air fried red potato wedges) and had no problem putting that away+ a bit of cake and ice cream.

Have no desire to eat fried foods however as the off-plan was meant to be a trip to Five Guys.
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@Ben10 Retatrutide feedback on 2mgs, reduced to 1mg/week.

https://www.evolutionary.org/forums...trutide-cutting-cycle-log.104299/post-1779382

Ben10 said:
Reta at 2mg was perfect, hunger suppressed significantly whilst doing big days at work and having a high output.

My output is slightly less so hunger is no where near as high so reduced to 1mg and still have appetite suppression. Will check BG levels Friday,sat,sun and compare to 2 weeks ago at 2mg and see if there any differences
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@Pigsy reporting on how 2.5mgs of retatrutide is going for him
https://www.evolutionary.org/forums/threads/pigsys-retatrutide-log.105320/post-1781699
Pigsy said:
The 2.5mg of Reta has really kicked in. Lucky have set times for meals, otherwise would forget. I noticed while working wasn't getting my water intake in as that seemed suppressed as well. So I put my water bottle ahead of me at work. So when get that spot take a drink. Morning BG is 4.2
While on 10ius of HGH. Without Reta was 4.7 to 4.8.
Thanks @ZenithHealth for trusting to log. Hope to continue
Click to expand...
 
@Atypical_CA asked if he can mix HCG with Retatrutide in the same syringe, we recommend against it.
https://www.evolutionary.org/forums/threads/retatrutide.103786/post-1785159
Atypical_CA said:
Sorry to raise an old thread but I’m looking for guidance. Does anybody mix/put their reta in the same syringe? I load Reta and hcg together, am I losing any effectiveness by doing this?
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Oracle911 said:
technically you can run peptides together if they are mixed in the same solution (bac water) but with certain ones like gh and reta mainly due to value i shoot them seperate, but things like tb500/bpc157 i put together and shoot and never had an issue hope this helps
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Atypical_CA said:
Thank you - I’ll try pinning separately for a month and see what happens… given the cost of Reta I should probably respect it a little more
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truthspeaker said:
Should never mix GLP1s with other peptides, common knowledge.
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LevButlerov said:
In theory you can, but I suggest splitting the Retatrutide and HCG in different pins. Especially with reta, you want to make sure there are no issues and you're getting the proper dosing. @Atypical_CA
Let me ask you, why do you want to use HCG with retatrutide? what is your cycle like here?
Click to expand...
 
Where can I buy Retatrutide for a reasonable pricing? Just bought my first 12 mg for 250 USD...
Im looking to stack up so I don't have to bother for a while.
Thankful for any help I get.
 
Börje said:
Where can I buy Retatrutide for a reasonable pricing? Just bought my first 12 mg for 250 USD...
Im looking to stack up so I don't have to bother for a while.
Thankful for any help I get.
Click to expand...
Where are you located
 
Börje said:
Where can I buy Retatrutide for a reasonable pricing? Just bought my first 12 mg for 250 USD...
Im looking to stack up so I don't have to bother for a while.
Thankful for any help I get.
Click to expand...

Börje said:
Im located in Sweden.
Click to expand...

Börje said:
Thanks a lot , I will look into those places.
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@Börje welcome to the EVO family :D
You should check umbrella labs or napsgear or ugfreak, they all have it
but not sure umbrella ships to Sweden

why are you using retatrutide? whats your goals with it?
 
@Blast asked a retatrutide question in his log
https://www.evolutionary.org/forums...-body-recomposition-cycle.105256/post-1793202
Blast said:
I’ve been researching a lot and I’ve decided to use Retatrutide for 10 weeks at 1mg a week to assist with fat burning. I’m interested to see if the Reta helps with the inflammation from my rheumatoid arthritis 🤔.
Click to expand...
My answer-

I’ve had a few clients try low dose Retatrutide at 1mg a week and they still saw steady fat loss over 8 to 10 weeks. It’s not just about the weight either since some noticed less joint pain and inflammation, which lines up with how GLP1 and GIP agonists work. Research from Nature Metabolism in 2023 shows GLP1 agonists can reduce inflammatory markers like IL6 and CRP. One diabetic client with RA even mentioned their hands felt better after a few weeks on it. Retatrutide works through multiple pathways so it might give broader relief beyond just blood sugar or appetite control.
 
New retatrutide log by @Flyingandrei
https://www.evolutionary.org/forums...e-cutting-log-with-ugl-oz.105842/post-1794943
Flyingandrei said:
Hey Evo fams i thought I'd start a seperate log for my reta use.

Start date 23/07/25.
2.5ml Bac water
5mg Reta

Week 1 dose 1mg.

I was advised to take 2mg but my body is usually very sensitive to things. I went with my instinct and sure enough...

After injecting a had a few hours nap and woke up super dehydrated. I don't feel as hungry lol. I will be doing occasional fasts on my reta cycle too. And upping the dossages dependant on the feedback i am getting.

Total gear
250mg test @UGL OZ
Retatrutide from @ZenithHealth

My scales have gone flat so I need to get a battery asap and update scale weight. Last time i checked i was around 21% bodyfat.
Goal is 12% as I want to add more test and possibly masteron / tren and shred up for summer.

Latest picture.
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@Flyingandrei Retatrutide update
https://www.evolutionary.org/forums...e-cutting-log-with-ugl-oz.105842/post-1801088
Flyingandrei said:
Just an update on almost finishing week 2 of reta.

Dose titration from 1mg to 1.5mg. Side affects slight upset stomach. Wasn't too crazy. 1.5mg i started to get a higher suppressed appetite.

It makes me feel like I don't care about food if I get it or not. Starting to add in fasted cardio on it starting tomorrow and also going to go in an agressive deficit

This week coming im going to try 2mg and stay with it if it suppresses even futher.
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@CookieMuncher reports sleep issues with retatrutide
https://www.evolutionary.org/forums/threads/retratrutide.106137/post-1807944
CookieMuncher said:
I got some serious side effects on retratrutide. Its liquid gold labs retra so im confident it is actually retra and my sides confirm it is retra too.

So, i started 30/07 doing 1.66666 mg per week.
Im on 20 mg lgd, 110mg trt dose. And thats it.
I was after just slight fat burning effect and slight appetite suppression.
My appetite got nuked, had to force myself to eat any meal. But most importantly, my sleep got completely destroyed.
I was still eating some meals so like 1500-1700 calories a day (i know i just couldn’t eat more) but at night time I had serious hypoglycemia symptoms. I am talking waking up 4-5x a night, in nightsweats, fucked dreams (i had a dream where i got recruited by fight club lmfao), anxiety, heart beating out my chest.
So few days ago I just had to cut it out because it was killing my strength + gains to be barely sleeping, and I didn’t expect it to make me hate eating at such a low dose…
Anyways so I did research and decided I should be eating carbs before bed and it helped a bit I guess but I had to go eat a tablespoon of honey whenever I woke up during the night, I sleep 11 pm wake up anywhere from 3-6 am.
Now that its slowly wearing off (I stopped only on 11/07) I can somewhat sleep again but is this common? Should I be worried haha? Can’t wait till the rest of this is out of my system, half life of 6 days so I’d expect 3-5 days more of this trouble.

I’ve done bloods like kidney, liver, metabolic panel and even fasting glucose and morning cortisol and that was all fine. I will admit its been a damn while since fasting glucose and morning cortisol test.
Also during this time I caught rhinovirus, common cold, and I thought the night sweats was from the virus but it turns out it was actually mostly retratrutide.
Click to expand...
 
LevButlerov said:
@CookieMuncher reports sleep issues with retatrutide
https://www.evolutionary.org/forums/threads/retratrutide.106137/post-1807944
Click to expand...
my answer
https://www.evolutionary.org/forums/threads/retratrutide.106137/post-1810120
LevButlerov said:
I added your feedback to our retatrutide mega thread here -
https://www.evolutionary.org/forums/threads/retatrutide-its-the-real-deal.103339
you should review that thread more @CookieMuncher
you should also update your log -
https://www.evolutionary.org/forums/threads/my-back-in-shape-trt-and-sarms-log.106154/

Sounds like the sleep issues are coming from a mix of low blood sugar and how retratrutide slows digestion. When you’re running TRT+LGD on top of it, your body is demanding fuel but the drug is blunting hunger and leaving you short on carbs. That drop in calories and glucose will spike cortisol and adrenaline at night, which is why you wake up sweaty, anxious, and wired. I’ve seen a few guys I train report the same thing, especially when they let carbs get too low in the first phase of use. Meaning, over time this gets easier.
Best approach is to keep pre-bed carbs in play, but NOT honey, best use steel cut oatmeal or another very log GI carb source.
Add Zinc Magnesium with valerian root as well, and if you can get melatonin add that too.
Click to expand...
 
LevButlerov said:
my answer
https://www.evolutionary.org/forums/threads/retratrutide.106137/post-1810120
Click to expand...
Also to add to this.
I tried taking carbs before bed with low GI like wholemeal toast + some protein like 20 g to further slow consumption. This significantly helped but i still woke up 5-6 hours into sleep approximately even on a low dose. Without that i was waking up 2-3x more often and earlier into sleep.
Also my fasting blood sugar has come back on the lower end of the within normal range when I got it done in the past, i dont know if that makes me more prone.
I also take zinc around 20 mg daily. I take magnesium l threonate 1500 mg, 100 mg apigenin and 200 mg l theanine before bed.
 
CookieMuncher said:
Also to add to this.
I tried taking carbs before bed with low GI like wholemeal toast + some protein like 20 g to further slow consumption. This significantly helped but i still woke up 5-6 hours into sleep approximately even on a low dose. Without that i was waking up 2-3x more often and earlier into sleep.
Also my fasting blood sugar has come back on the lower end of the within normal range when I got it done in the past, i dont know if that makes me more prone.
I also take zinc around 20 mg daily. I take magnesium l threonate 1500 mg, 100 mg apigenin and 200 mg l theanine before bed.
Click to expand...
My answer in thread -
https://www.evolutionary.org/forums/threads/retratrutide.106137/post-1810265
LevButlerov said:
Switch to whole or steel cut oats mixed with caseinate protein, before bed with 2-3 walnuts, this will fix the issue for now. Don't do toast. @CookieMuncher

Add valerian in this case, and you can ignore the melatonin, I think you need a prescription in AU for it! (nuts!)
Click to expand...
 
@ashsplash Retatrutide kick in question
https://www.evolutionary.org/forums/threads/my-pre-cycle-log.105622/post-1811160
ashsplash said:
@Is it true that Reta takes longer to kick in? Because with Tirzepatide in the past I`ve noticed changes in appetite already on the second/third day; and what dosage relation between these two compound would you suggest?
Click to expand...
My answer
https://www.evolutionary.org/forums/threads/my-pre-cycle-log.105622/post-1811166
LevButlerov said:
Yes for sure takes longer to kick in about a week or 2 @ashsplash

and read our retatrutide mega thread
https://www.evolutionary.org/forums/threads/retatrutide-its-the-real-deal.103339
Click to expand...
 
I have been on Tirz for a few months now and switched to reta since a month. Started 1.5mg first week and 2mg/week thereafter at 1mg twice a week. 4 weeks in and I must say this drug is a bit strong for me.

Few problems I noted:
1) Constipation. Reta seems to work the opposite for everybody and they poop well but then 8% of the test subjects had this issue. It seems like the glucogon component causes intestine relaxation - https://pmc.ncbi.nlm.nih.gov/articles/PMC1413155/ I had no issues on Tirz. Though both constituted to slight levels of depression.
2) Fatigue. Reta fatigue and brain fog is real. I am always tired all the time. I have been using a CGM to monitor my sugarlevels from a few days and its not like its dropping low. But its around 4.5mmol/L.
3) The GLP component is weak, on 2 mg i barely notice appetite suppression, where as on 2mg tirz, it was quite powerful.
4) The GIP component is too strong. Everytime I have a meal, the blood sugar is supressed so low that it almost reaches 3.1 mmol/L. For reference, my fasting glucose levels are 4.2mmol/L. So the influx of insulin followed by sudden drop in sugar levels both are affecting me bad that I ahve to sleep after every food intake.

Any weight loss you ask? Nothing noticeble in the last month or so, but my wokouts have taken a backseat nowadays. Any weight loss i see is probably due to loss is muscle water retention due to lack of workout.

I am going to try one more injection this friday and put the rest of the reconstitued liquid into the freezer and order some Tirz if things dont settle.
Hope this helps folks who are in similar boat.

EDIT: I have also been taking tryptophan since a week, I will stop that and see if thats causing any issues.
 
nojo mackar said:
I have been on Tirz for a few months now and switched to reta since a month. Started 1.5mg first week and 2mg/week thereafter at 1mg twice a week. 4 weeks in and I must say this drug is a bit strong for me.

Few problems I noted:
1) Constipation. Reta seems to work the opposite for everybody and they poop well but then 8% of the test subjects had this issue. It seems like the glucogon component causes intestine relaxation - https://pmc.ncbi.nlm.nih.gov/articles/PMC1413155/ I had no issues on Tirz. Though both constituted to slight levels of depression.
2) Fatigue. Reta fatigue and brain fog is real. I am always tired all the time. I have been using a CGM to monitor my sugarlevels from a few days and its not like its dropping low. But its around 4.5mmol/L.
3) The GLP component is weak, on 2 mg i barely notice appetite suppression, where as on 2mg tirz, it was quite powerful.
4) The GIP component is too strong. Everytime I have a meal, the blood sugar is supressed so low that it almost reaches 3.1 mmol/L. For reference, my fasting glucose levels are 4.2mmol/L. So the influx of insulin followed by sudden drop in sugar levels both are affecting me bad that I ahve to sleep after every food intake.

Any weight loss you ask? Nothing noticeble in the last month or so, but my wokouts have taken a backseat nowadays. Any weight loss i see is probably due to loss is muscle water retention due to lack of workout.

I am going to try one more injection this friday and put the rest of the reconstitued liquid into the freezer and order some Tirz if things dont settle.
Hope this helps folks who are in similar boat.

EDIT: I have also been taking tryptophan since a week, I will stop that and see if thats causing any issues.
Click to expand...
@nojo mackar welcome to the EVO family :D seen a few of your posts but this is the first feedback I've seen.
  1. The constipation is from the glucagon effect in Retatrutide slowing your gut. On Tirzepatide you did not experience this which means your body responded better to that balance. Without knowing your diet, probiotic, psyllium fiber intake, digestive enzyme intake, this says really nothing.
  2. The fatigue and brain fog come from running at the lower end of blood sugar around 4.5 mmol/L. Even though it is not technically hypo it is still enough to leave you drained all day. That again is diet and training related NOT reta related.
  3. The appetite suppression is weak because the GLP side of Retatrutide is not as strong as Tirzepatide so you are not getting that strong hunger control you had before.
  4. The GIP (glucose-dependent insulinotropic polypeptide) response in Retatrutide is too strong for you which explains the sharp drops after meals that push your blood sugar down and make you need to sleep.
Your lack of weight loss ties into training taking a backseat and most of what you see on the scale is water and glycogen rather than fat. Freezing the leftover Retatrutide and going back to Tirzepatide is a smart plan since you know you tolerated that much better. Dropping tryptophan is also a good idea because it can worsen fatigue and mood so you can clearly see if Retatrutide alone is causing the issues.

In reality, the real deep rooted issue here is that you don't have a LOG Journal on EVO which we can use to guide and help you with. We need you to share your LOG journal in a NEW thread, this way the whole EVO family can guide you on this journey and make sure you have better results.
 
LevButlerov said:
@nojo mackar welcome to the EVO family :D seen a few of your posts but this is the first feedback I've seen.
  1. The constipation is from the glucagon effect in Retatrutide slowing your gut. On Tirzepatide you did not experience this which means your body responded better to that balance. Without knowing your diet, probiotic, psyllium fiber intake, digestive enzyme intake, this says really nothing.
  2. The fatigue and brain fog come from running at the lower end of blood sugar around 4.5 mmol/L. Even though it is not technically hypo it is still enough to leave you drained all day. That again is diet and training related NOT reta related.

In reality, the real deep rooted issue here is that you don't have a LOG Journal on EVO which we can use to guide and help you with. We need you to share your LOG journal in a NEW thread, this way the whole EVO family can guide you on this journey and make sure you have better results.
Click to expand...
Thanks Brother.
1) Diet wise, nothing has changed. I have taken psyllium husk, Mag citrate, senna, triphala and nothing has helped. Its like gut went to sleep haha.
2) Dunno if blood sugar was tht level on Tirz, as I did not have CGM then. Food levels have infact increasd due to lack of appetite supressipn bro. So its the GIP.

What is logging mate? Is it like I ahve to put all my workouts and food on one page?
 
nojo mackar said:
Thanks Brother.
1) Diet wise, nothing has changed. I have taken psyllium husk, Mag citrate, senna, triphala and nothing has helped. Its like gut went to sleep haha.
2) Dunno if blood sugar was tht level on Tirz, as I did not have CGM then. Food levels have infact increasd due to lack of appetite supressipn bro. So its the GIP.

What is logging mate? Is it like I ahve to put all my workouts and food on one page?
Click to expand...
@nojo mackar good to see you get back to the convo :D
  1. If the psyllium husk, magnesium citrate, senna, and triphala are not helping then that shows the Retatrutide is slowing the gut too much for you. On Tirzepatide your digestion worked better so that GLP1 suited your system more.
  2. You did not have a CGM on Tirzepatide so you cannot compare numbers but you did not feel this level of fatigue back then which means your sugar swings were not as severe.
  3. The increase in food intake comes from the weak GLP effect in Retatrutide since it does not give the same appetite control you had on Tirzepatide.
  4. The GIP side is hitting too strong and that is why your sugar drops after meals and you feel like crashing every time you eat.
All of these issues line up with Retatrutide not being the right fit for you right now. Tirzepatide gave you smoother digestion, better energy and stronger appetite suppression so returning to it makes sense. But in the end the food and diet and training are going to be the sticky point here.

nojo mackar said:
What is logging mate? Is it like I ahve to put all my workouts and food on one page?
Click to expand...
Good question! a Log is a journal which helps us guide and help you on your journey to success. It allows the whole EVO family to help and support you. Its easy to start a log, just start a new threads share your diet training cardio sleep cycle supp use and history and we guide you from there, its ongoing, takes 15min to start and 5min weekly to update very easy. Here is the directions.

HOW-TO LOG?
  • To really guide you we need more info from you.
  • Please share your diet, training, cardio, sleep, supplements etc log with us in a NEW thread, full log journal so our guidance is based on facts you provide.
  • It will take 15-20 minutes max.
  • We have 100s of years of experience between us, so you need to post a LOG Journal with your stats (weight,height,age, years training, cycle history) diet, training, cardio, supplement, sleep details. If you don't log what you eat or train now, open NOTES on phone and start recording it there and paste here. Very easy.
Please post a Log Journal asap for us

Please click the anabolic forum
https://www.evolutionary.org/forums/forums/anabolic-steroids-and-peds.2/
top RIGHT, you see: +POST THREAD
click that

in Title: write your cycle name, like> My _____ Cycle Log
___ = the name of your log
example: My cycle training diet Log
in body: write your planned cycle or cycle you doing now, your diet, training and we will help you along on your cycle

here are examples of LOG Journals

https://www.evolutionary.org/forums/threads/s-gentz-recomp-cut-log-2023-2024.96694/
https://www.evolutionary.org/forums/threads/mobsters-training-diary.84438/
https://www.evolutionary.org/forums/threads/roidrage69-log.90127
https://www.evolutionary.org/forums/threads/domestic-supply-bulking-log-25homes-max.97609/
https://www.evolutionary.org/forums...obolan-equipoise-tbol-contest-prep-log.97138/
https://www.evolutionary.org/forums...osterone-deca-primobolan-hgh-cycle-log.97978/
https://www.evolutionary.org/forums...igas-hgh-and-bpc157-recovery-cycle-log.97594/
https://www.evolutionary.org/forums...enbolone-cycle-log-let-the-gains-begin.98399/
https://www.evolutionary.org/forums/threads/pigsy-new-sponsor-ugl-contest-prep-log.96779/
https://www.evolutionary.org/forums/threads/my-2023-2024-log.95956/
https://www.evolutionary.org/forums...stosterone-cardarine-cutting-cycle-log.97281/
https://www.evolutionary.org/forums/threads/roidragewife-female-training-log.95769/
https://www.evolutionary.org/forums/threads/2024-lean-bulking-cycle-log.97986/
https://www.evolutionary.org/forums/threads/my-trt-with-deca-durabolin-log.97962/
https://www.evolutionary.org/forums...bodybuilding-log-masters-55-competitor.97210/
https://www.evolutionary.org/forums/threads/losiol-primobolan-testosterone-log.96581/
https://www.evolutionary.org/forums/threads/roughy-steroid-cycle-and-training.97944/
https://www.evolutionary.org/forums/threads/fatboy999-2024-cycle-log.97936/
https://www.evolutionary.org/forums/threads/testosterone-equipoise-trenbolone-cycle-log.96963/
https://www.evolutionary.org/forums/threads/my-trt-log.98284/
https://www.evolutionary.org/forums/threads/16-week-testosterone-cardarine-n2guard-cycle-log.98034/
https://www.evolutionary.org/forums/threads/training-log-female.90425
https://www.evolutionary.org/forums...tosterone-masteron-primobolan-blast-log.98328
https://www.evolutionary.org/forums/threads/25homes-revenge-transformation-log-2023.88570/
https://www.evolutionary.org/forums...n-season-sponsored-by-nordic-fusion-log.89817
https://www.evolutionary.org/forums/threads/s-gentz-contest-prep-log.87619/

P.S. are you listening to our podcast? if not, you should; this podcast is about steroids, sarms, peptides, and bodybuilding:
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